LEADER 03679nam 22005891 450 001 9910961458503321 005 20251116200141.0 010 $a1-908986-35-2 035 $a(CKB)3710000000083536 035 $a(EBL)3410348 035 $a(SSID)ssj0001085890 035 $a(PQKBManifestationID)11591654 035 $a(PQKBTitleCode)TC0001085890 035 $a(PQKBWorkID)11055177 035 $a(PQKB)11503856 035 $a(MiAaPQ)EBC3410348 035 $a(Au-PeEL)EBL3410348 035 $a(CaPaEBR)ebr10827979 035 $a(CaONFJC)MIL577703 035 $a(OCoLC)923424599 035 $a(BIP)50060772 035 $a(BIP)13736153 035 $a(EXLCZ)993710000000083536 100 $a20070918d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 02$aA guide to cancer genetics in clinical practice /$fedited by Sue Clark 205 $aFirst edition. 210 1$aHarley [England] :$cTFM,$d2009. 215 $a1 online resource (246 p.) 300 $aDescription based upon print version of record. 311 08$a1-903378-54-0 320 $aIncludes bibliographical references. 327 $a""COVER FRONT""; ""Contents""; ""Foreword""; ""Contributors""; ""Chapter 1 Genetics is not complicated""; ""Chapter 2 Genetics and cancer""; ""Chapter 3 Ethical and legal aspects of cancer genetics""; ""Chapter 4 Familial adenomatous polyposis""; ""Chapter 5 MYH-associated polyposis""; ""Chapter 6 Lynch syndrome (hereditary non-polyposis colorectal cancer)""; ""Chapter 7 Breast cancer""; ""Chapter 8 The gynaecologist and inherited cancer""; ""Chapter 9 Multiple endocrine neoplasia syndromes""; ""Chapter 10 Neurofibromatosis""; ""Chapter 11 Familial gastric cancer"" 327 $a""Chapter 12 Familial pancreatic cancer""""Chapter 13 Hamartomatous polyposis syndromes""; ""Chapter 14 The future structure of care: cancer genetics""; ""COVER BACK"" 330 $aFIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions. 606 $aCancer$xGenetic aspects 606 $aCancer genes 615 0$aCancer$xGenetic aspects. 615 0$aCancer genes. 676 $a616.994042 701 $aClark$b Sue$cMD.$01868599 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910961458503321 996 $aA guide to cancer genetics in clinical practice$94476566 997 $aUNINA