LEADER 04283nam 2200721 a 450 001 9910961017203321 005 20251017110114.0 010 $a9786610186457 010 $a9780309173797 010 $a0309173795 010 $a9781280186455 010 $a1280186453 010 $a9780309580526 010 $a0309580528 010 $a9780585155760 010 $a0585155763 035 $a(CKB)110986584752358 035 $a(OCoLC)44964205 035 $a(CaPaEBR)ebrary10056980 035 $a(SSID)ssj0000169499 035 $a(PQKBManifestationID)11155450 035 $a(PQKBTitleCode)TC0000169499 035 $a(PQKBWorkID)10204121 035 $a(PQKB)10270561 035 $a(Au-PeEL)EBL3376703 035 $a(CaPaEBR)ebr10056980 035 $a(OCoLC)817959237 035 $a(MiAaPQ)EBC3376703 035 $a(Perlego)4736367 035 $a(DNLM)894627 035 $a(BIP)47693827 035 $a(EXLCZ)99110986584752358 100 $a19981029d1998 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHealth effects of exposure to low levels of ionizing radiations $etime for reassessment? /$fCommittee on Health Effects of Exposure to Low Levels of Ionizing Radiations, Board on Radiation Effects Research, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 $aWashington, D.C. $cNational Academy Press$d1998 215 $a1 online resource (86 p.) 225 1 $aBEIR ;$v7 225 1 $aThe Compass series 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780309061766 311 08$a0309061768 320 $aIncludes bibliographical references (p. 51-72) and index. 327 $aHealth Effects of Exposure to Low Levels of Ionizing Radiations -- Copyright -- Preface -- Contents -- EXECUTIVE SUMMARY -- 1 INTRODUCTION -- 2 EPIDEMIOLOGIC INVESTIGATIONS -- NEW EPIDEMIOLOGIC RESULTS -- ADVANCES IN METHODOLOGY -- CONSIDERATIONS FOR A BEIR VII PHASE-2 COMMITTEE -- RADIOEPIDEMIOLOGIC TABLES -- 3 CELLULAR AND MOLECULAR CONSIDERATIONS -- DNA DAMAGE AND ITS REPAIR -- CONCLUSIONS -- CONDITIONED AND INDUCIBLE RESPONSES TO RADIATION -- CONCLUSIONS -- CHROMOSOMAL ABERRATIONS AND MUTATIONS -- Chromosomal Aberrations -- Mutations -- CONCLUSIONS -- 4 ANIMAL STUDIES -- CONCLUSIONS -- 5 RADIOBIOLOGIC PRINCIPLES AND RISK MODELING -- LINEARITY VERSUS CURVILINEARITY -- THE DOSE DEPENDENCE OF RBE -- POTENTIAL IMPACT OF NEUTRONS -- CONCLUSIONS -- 6 MATHEMATICAL MODELS OF RADIATION CARCINOGENESIS -- THE TWO-MUTATION MODEL -- IMPLICATIONS OF THE MODEL FOR RISK ESTIMATION -- CONCLUSIONS -- LITERATURE CITED -- Information on Committee Members -- List of Acronyms -- ACKNOWLEDGMENTS. 330 $aThe US Environmotection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment. 410 0$aBEIR (Series) ;$v7. 410 0$aCompass series (Washington, D.C.) 606 $aLow-level radiation$xHealth aspects 615 0$aLow-level radiation$xHealth aspects. 676 $a616.9/897 712 02$aNational Research Council (U.S.).$bCommittee on Health Effects of Exposure to Low Levels of Ionizing Radiations. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910961017203321 996 $aHealth effects of exposure to low levels of ionizing radiations$94359557 997 $aUNINA