LEADER 02849oam 2200601I 450 001 9910960954203321 005 20251117093735.0 010 $a1-4987-5298-5 010 $a1-315-37435-8 010 $a1-4665-6551-9 024 7 $a10.1201/9781315374352 035 $a(CKB)3710000001387623 035 $a(MiAaPQ)EBC4862400 035 $a(Au-PeEL)EBL4862400 035 $a(CaPaEBR)ebr11386621 035 $a(CaONFJC)MIL1011650 035 $a(OCoLC)987790994 035 $a(FINmELB)ELB147465 035 $a(BIP)59529993 035 $a(BIP)39568030 035 $a(EXLCZ)993710000001387623 100 $a20180706h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAlgorithms for next-generation sequencing /$fWing-Kin Sung 205 $a1st ed. 210 1$aBoca Raton, FL :$cCRC Press, Taylor & Francis Group,$d[2017] 210 4$dİ2017 215 $a1 online resource (347 pages) $cillustrations 225 1 $aChapman & Hall/CRC Mathematical and Computational Biology Series 300 $a"A Chapman & Hall book." 311 08$a1-4665-6550-0 320 $aIncludes bibliographical references and index. 327 $a1. Introduction -- 2. NGS file formats -- 3. Related algorithms and data structures -- 4. NGS read mapping -- 5. Genome assembly -- 6. Single nucleotide variation (SNV) calling -- 7. Structural variation calling -- 8. RNA-seq -- 9. Peak calling methods -- 10. Data compression techniques used in NGS files. 330 $aAdvances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before - as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for Next-Generation Sequencing is an invaluable tool for students and researchers in bioinformatics and computational biology, biologists seeking to process and manage the data generated by next-generation sequencing, and as a textbook or a self-study resource. In addition to offering an in-depth description of the algorithms for processing sequencing data, it also presents useful case studies describing the applications of this technology. 410 0$aChapman and Hall/CRC mathematical & computational biology series. 606 $aBioinformatics 606 $aNucleotide sequence 606 $aGenetic algorithms 615 0$aBioinformatics. 615 0$aNucleotide sequence. 615 0$aGenetic algorithms. 676 $a570.285 700 $aSung$b Wing-Kin$01865911 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910960954203321 996 $aAlgorithms for next-generation sequencing$94481014 997 $aUNINA