LEADER 04557nam 22007574a 450 001 9910960857903321 005 20251017110103.0 010 $a9780309132756 010 $a0309132754 010 $a9780309519311 010 $a0309519314 010 $a9780585215556 010 $a0585215553 035 $a(CKB)110986584752720 035 $a(EBL)3375552 035 $a(SSID)ssj0000240591 035 $a(PQKBManifestationID)12044625 035 $a(PQKBTitleCode)TC0000240591 035 $a(PQKBWorkID)10265390 035 $a(PQKB)10459544 035 $a(MiAaPQ)EBC3375552 035 $a(Au-PeEL)EBL3375552 035 $a(CaPaEBR)ebr10040969 035 $a(OCoLC)880597823 035 $a(Perlego)4735624 035 $a(DNLM)893174 035 $a(BIP)53858940 035 $a(BIP)44084000 035 $a(EXLCZ)99110986584752720 100 $a19990726d2000 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSafety of silicone breast implants /$fStuart Bondurant, Virginia Ernster, and Roger Herdman, editors ; Committee on the Safety of Silicone Breast Implants, Division of Health Promotion and Disease Prevention, Institute of Medicine 205 $a1st ed. 210 $aWashington, D.C. $cInstitute of Medicine$dc2000 215 $a1 online resource (558 pages) 300 $aDescription based upon print version of record. 311 0 $a9780309157407 311 0 $a0309157404 311 0 $a9780309065320 311 0 $a0309065321 320 $aIncludes bibliographical references (p. 285-479) and index. 327 $a""Front Matter""; ""Reviewers""; ""Preface""; ""Contents""; ""Executive Summary""; ""1 Introduction""; ""2 Silicone Chemistry""; ""3 Implant Catalogue""; ""4 Silicone Toxicology""; ""5 Reoperations and Specific Local and Perioperative Complications""; ""6 Immunology of Silicone""; ""7 Antinuclear Antibodies and Silicone Breast Implants""; ""8 Epidemiological Studies of Connective Tissue or Rheumatic Diseases and Breast Implants""; ""9 Silicone Breast Implants and Cancer""; ""10 Neurologic Disease and Its Association with Silicone Breast Implants"" 327 $a""11 Effects on Pregnancy, Lactation, and Children"" ""12 Silicone Implants and Breast Imaging""; ""Reference Lists""; ""APPENDIX A Brief Description of the Scientific Workshop""; ""APPENDIX B Description of the Public Meeting""; ""APPENDIX B Description of the Public Meeting""; ""APPENDIX C Review of the Reports of the Independent Review Group and the National Science Panel""; ""APPENDIX D Glossary""; ""Index"" 330 $aThe Dow Corning case raised serious questions about the safety of silicone breast implants and about larger issues of medical device testing and patient education. Safety of Silicone Breast Implants presents a well-documented, thoughtful exploration of the safety of these devices, drawing conclusions from the available research base and suggesting further questions to be answered. This book also examines the sensitive issues surrounding women's decisions about implants. In reaching conclusions, the committee reviews: The history of the silicone breast implant and the development of its chemistry. The wide variety of U.S.-made implants and their regulation by the Food and Drug Administration. Frequency and consequences of local complications from implants. The evidence for and against links between implants and autoimmune disorders, connective tissue disease, neurological problems, silicone in breast milk, or a proposed new syndrome. Evidence that implants may be associated with lower frequencies of breast cancer. Safety of Silicone Breast Implants provides a comprehensive, well-organized review of the science behind one of the most significant medical controversies of our time. 606 $aBreast implants$xComplications 606 $aSilicones$xToxicology 606 $aMammaplasty 615 0$aBreast implants$xComplications. 615 0$aSilicones$xToxicology. 615 0$aMammaplasty. 676 $a618.1/90592 701 $aBondurant$b Stuart$01806334 701 $aErnster$b Virginia L$01806335 701 $aHerdman$b Roger$01806336 712 02$aInstitute of Medicine (U.S.).$bCommittee on the Safety of Silicone Breast Implants. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910960857903321 996 $aSafety of silicone breast implants$94355457 997 $aUNINA