LEADER 00759nam0-2200289---450- 001 990009574130403321 005 20120516124435.0 010 $a8496099660 035 $a000957413 035 $aFED01000957413 035 $a(Aleph)000957413FED01 035 $a000957413 100 $a20120516d2004----km-y0itay50------ba 101 0 $aita 102 $aES 105 $aa-------001yy 200 1 $aHotel accoglienti$fJessica Lawson 210 $aBarcellona$cAtrium$d2004 215 $a174 p.$cin gran parte ill.$d27 cm 700 1$aLawson,$bJessica$0516517 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009574130403321 952 $aARR B 114$b18822$fFARBC 959 $aFARBC 996 $aHotel accoglienti$9846292 997 $aUNINA LEADER 06510nam 22011053u 450 001 9910960698303321 005 20230803025055.0 010 $a9781299132184 010 $a1299132189 010 $a9781119941057 010 $a1119941059 010 $a9781119942665 010 $a1119942667 035 $a(CKB)2670000000315452 035 $a(EBL)1108507 035 $a(OCoLC)823718924 035 $a(SSID)ssj0000803943 035 $a(PQKBManifestationID)11430592 035 $a(PQKBTitleCode)TC0000803943 035 $a(PQKBWorkID)10813780 035 $a(PQKB)10358576 035 $a(MiAaPQ)EBC1108507 035 $a(MiAaPQ)EBC4956632 035 $a(Au-PeEL)EBL4956632 035 $a(CaONFJC)MIL444468 035 $a(OCoLC)1027169054 035 $a(Perlego)1002338 035 $a(EXLCZ)992670000000315452 100 $a20131230d2013|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aExtreme Tissue Engineering $eConcepts and Strategies for Tissue Fabrication 205 $a1st ed. 210 $aHoboken $cWiley$d2013 215 $a1 online resource (270 p.) 300 $aDescription based upon print version of record. 311 08$a9780470974469 311 08$a047097446X 327 $aExtreme Tissue Engineering; Contents; Preface: Extreme Tissue Engineering-a User's Guide; Chapter 1 Which Tissue Engineering Tribe Are You From?; 1.1 Why do we need to engineer tissues at all?; 1.1.1 Will the real tissue engineering and regenerative medicine please stand up?; 1.1.2 Other people's definitions; 1.1.3 Defining our tissue engineering: fixing where we are on the scale-hierarchy; 1.2 Bio-integration as a fundamental component of engineering tissues; 1.2.1 Bio-scientists and physical scientists/engineers: understanding diversity in TERM 327 $a1.3 What are the `tribes' of tissue engineering?1.3.1 Special needs for special characteristics: why is networking essential for TERM?; 1.4 Surprises from tissue engineering (Veselius to Vacanti); 1.5 So, really, is there any difference between tissue engineering and regenerative medicine?; 1.5.1 Questions never really asked: repair versus regeneration?; 1.5.2 Understanding the full spectrum: tissue replacement, repair and regeneration; 1.6 Conclusions; 1.7 Summarizing definitions; Annex 1 Other people's definitions of tissue engineering 327 $aAnnex 2 Other people's definitions of regenerative medicineFurther reading; Chapter 2 Checking Out the Tissue Groupings and the Small Print; 2.1 Checking the small print: what did we agree to engineer?; 2.2 Identifying special tissue needs, problems and opportunities; 2.3 When is `aiming high' just `over the top'?; 2.4 Opportunities, risks and problems; 2.4.1 Experimental model tissues (as distinct from spare-parts and fully regenerated tissues); 2.4.2 The pressing need for 3D model tissues; 2.4.3 Tissue models can be useful spin-offs on the way to implants 327 $a2.5 Special needs for model tissues2.5.1 Cell selection: constancy versus correctness; 2.5.2 Support matrices-can synthetics fake it?; 2.5.3 Tissue dimensions: when size does matter!; 2.6 Opportunities and sub-divisions for engineering clinical implant tissues; 2.6.1 Making physiological implants: spare parts or complete replacement?; 2.6.2 Making pathological and aphysiological constructs: inventing new parts and new uses; 2.6.3 Learning to use the plethora of tissue requirements as an opportunity; 2.7 Overall summary; Further reading; Chapter 3 What Cells `Hear' When We Say `3D' 327 $a3.1 Sensing your environment in three dimensions: seeing the cues3.2 What is this 3D cell culture thing?; 3.3 Is 3D, for cells, more than a stack of 2Ds?; 3.4 On, in and between tissues: what is it like to be a cell?; 3.5 Different forms of cell-space: 2D, 3D, pseudo-3D and 4D cell culture; 3.5.1 What has `3D' ever done for me?; 3.5.2 Introducing extracellular matrix; 3.5.3 Diffusion and mass transport; 3.5.4 Oxygen mass transport and gradients in 3D engineered tissues: scaling Mount Doom; 3.6 Matrix-rich, cell-rich and pseudo-3D cell cultures 327 $a3.7 4D cultures-or cultures with a 4th dimension? 330 $aHighly Commended at the BMA Book Awards 2013 Extreme Tissue Engineering is an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field. Organised into three main sections: chapters 1 to 3 introduce and e 606 $aCell Culture Techniques 606 $aRegenerative Medicine - methods 606 $aTissue Engineering 606 $aTissue Scaffolds 606 $aCulture Techniques 606 $aInvestigative Techniques 606 $aMedicine 606 $aCulture Media 606 $aProstheses and Implants 606 $aEquipment and Supplies 606 $aHealth Occupations 606 $aClinical Laboratory Techniques 606 $aMethods 606 $aTissue Scaffolds 606 $aRegenerative Medicine 606 $aCell Culture Techniques 606 $aTissue Engineering 606 $aHealth & Biological Sciences$2HILCC 606 $aBiomedical Engineering$2HILCC 615 4$aCell Culture Techniques. 615 4$aRegenerative Medicine - methods. 615 4$aTissue Engineering. 615 4$aTissue Scaffolds. 615 2$aCulture Techniques. 615 2$aInvestigative Techniques. 615 2$aMedicine. 615 2$aCulture Media. 615 2$aProstheses and Implants. 615 2$aEquipment and Supplies. 615 2$aHealth Occupations. 615 2$aClinical Laboratory Techniques. 615 2$aMethods. 615 2$aTissue Scaffolds. 615 2$aRegenerative Medicine. 615 2$aCell Culture Techniques. 615 2$aTissue Engineering. 615 7$aHealth & Biological Sciences 615 7$aBiomedical Engineering 676 $a571.538 700 $aBrown$b Robert A$0148987 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910960698303321 996 $aExtreme Tissue Engineering$94368037 997 $aUNINA