LEADER 01775nam 2200361 n 450 001 996388810603316 005 20221108104958.0 035 $a(CKB)1000000000644329 035 $a(EEBO)2269045433 035 $a(UnM)99836908 035 $a(EXLCZ)991000000000644329 100 $a19900924d1565 uh | 101 0 $aeng 135 $aurbn||||a|bb| 200 12$aA collection of all the statutes, from the begynning of Magna Carta, vnto the yeare of our Lorde (1557.) which were before that yeare imprinted$b[electronic resource] $eWhereunto be added the collection of the statutes, made in the fourth and fifth yeares of the reignes of King Philip & Queene Marye: and also the statutes made in the first, and fifth yeare of the raigne of our soueraigne ladye Queene Elizabeth. And first an epistle, necessary to be read by them that shall vse thys booke 210 $a[London] $cIn �dibus Richardi Tottelli$dAnno. 1565. die Maij. 26 215 $a[6], 619, [1] leaves 300 $aEdited by William Rastall, whose name appears in the heading to the introduction, and continued by another hand. 300 $aAt foot of title: Cum priuilegio Regiæ Maiestatis. 300 $aIncludes index. 300 $aThe last leaf is blank. 300 $aReproduction of the original in the Henry E. Huntington Library and Art Gallery. 330 $aeebo-0113 701 $aRastell$b William$f1508?-1565.$01001637 712 02$aEngland.$4aut 801 0$bCu-RivES 801 1$bCu-RivES 801 2$bCStRLIN 801 2$bWaOLN 906 $aBOOK 912 $a996388810603316 996 $aA collection of all the statutes, from the begynning of Magna Carta, vnto the yeare of our Lorde (1557.) which were before that yeare imprinted$92386652 997 $aUNISA LEADER 01043ogm 2200253z- 450 001 9910319804003321 005 20241113235159.0 024 7 $a10.3791/58124-v 035 $a(CKB)4910000000115700 035 $a(EXLCZ)994910000000115700 100 $a20240702j20180901 uy v 101 0 $aeng 200 10$aDisentangling high strength copolymer aramid fibers to enable the determination of their mechanical properties /$fAmanda L. 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-- 1.4 INSTITUTIONAL POLICIES AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION -- REFERENCES -- 2 Ethical and Scientific Issues -- 2.1 DEFINITIONS -- 2.2 CONCEPTUAL FRAMEWORK FOR ETHICAL DECISIONS (ROBB, 1989) -- 2.3 ARGUMENTS USED BY THOSE ADVOCATING THE HUMANE USE OF ANIMALS FOR HUMAN PURPOSES (CAPLAN, 1984) -- 2.4 ARGUMENTS USED BY ANIMAL-RIGHTS ADVOCATES (SINGER, 1975 -- REGAN, 1983) -- 2.5 THE ROLE OF LAWS, REGULATIONS, AND POLICIES -- 2.6 SUGGESTED ETHICAL PRINCIPLES (SEE U.S. GOVERNMENT PRINCIPLES FOR THE UTILIZATION AND CARE OF VERTEBRATE ANIMALS USED IN? -- REFERENCES -- 3 Alternatives -- 3.1 DEFINITIONS -- 3.2 RATIONALE FOR CONSIDERING ALTERNATIVES -- 3.3 NONANIMAL RESEARCH METHODS AND MODELS -- 3.4 FACTORS INFLUENCING MODEL SELECTION -- 3.5 UTILIZATION OF SERVICES -- REFERENCES -- 4 Responsibilities of the Institution, the Animal Care and Use Committee, and the Research and Veterinary Staffs -- 4.1 RESPONSIBILITIES OF THE INSTITUTION -- 4.2 RESPONSIBILITIES OF THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC) -- 4.3 RESPONSIBILITIES OF THE INVESTIGATOR (THE TERM INVESTIGATOR IS USED BROADLY TO DESIGNATE THOSE PEOPLE RESPONSIBLE? -- 4.4 RESPONSIBILITIES OF THE ATTENDING VETERINARIAN (SEE 9 CFR 2.33) -- REFERENCES -- 5 Pain and Distress -- 5.1 DEFINITIONS -- 5.2 CATEGORIES OF PAIN (AVMA, 1986) -- 5.3 PAIN PERCEPTION -- 5.4 ASSESSMENT OF PAIN (AVMA, 1986) -- 5.5 STRESS (NRC, IN PRESS) -- 5.6 DISTRESS (NRC, IN PRESS) -- 5.7 ETHICAL OBLIGATIONS -- 5.8 LEGAL OBLIGATIONS (OVERSEEN BY THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE) -- 5.9 ADEQUATE VETERINARY CARE -- REFERENCES -- 6 Anesthetics, Tranquilizers, Analgescis, and Neuromuscular Blocking Agents. 327 $a6.1 GENERAL ANESTHETICS (LUMB AND JONES, 1984) -- 6.2 TRANQUILIZERS AND SEDATIVES (GLEED, 1987) -- 6.3 Analgesics -- 6.4 NEUROMUSCULAR BLOCKING AGENTS (PARALYTICS OR IMMOBILIZING AGENTS) -- 6.5 FACTORS MODIFYING THE EFFECTS OF TRANQUILIZERS, ANALGESICS, AND NEUROMUSCULAR BLOCKING AGENTS -- 6.6 SAFETY PRECAUTIONS -- 6.7 RECORDKEEPING REQUIREMENTS -- 6.8 FUNCTIONS OF THE ATTENDING VETERINARIAN IN PAIN MANAGEMENT -- REFERENCES -- 7 Survival Surgery and Postsurgical Care -- 7.1 DEFINITIONS -- 7.2 LEGAL REQUIREMENTS (9 CFR 2.31 -- PHS, 1986) -- 7.3 PREPARATION FOR SURGERY -- 7.4 ANESTHESIA (SEE SECTION 6.1) -- 7.5 SURGICAL COMPLICATIONS -- 7.6 INCISIONS -- 7.7 POSTSURGICAL CARE -- 7.8 EQUIPMENT: TYPE NEEDED TO PROPERLY SUPPORT SURGICAL PROCEDURES IS DEPENDENT ON A NUMBER OF VARIABLES, INCLUDING THE? -- 7.9 RECORDKEEPING -- REFERENCES -- 8 Euthanasia -- 8.1 DEFINITION -- 8.2 LEGAL REQUIREMENTS -- 8.3 ETHICAL AND HUMANE CONSIDERATIONS -- 8.4 HUMAN CONSIDERATIONS -- 8.5 CRITERIA FOR SELECTION OF METHOD OF EUTHANASIA -- 8.6 Pharmacologic Methods -- 8.7 PHYSICAL METHODS -- 8.8 Carcass Disposal -- REFERENCES -- 9 Husbandry, Care, and the Importance of the Environment -- 9.1 LEGAL REQUIREMENTS FOR HUSBANDRY AND CARE -- 9.2 IMPORTANCE OF PROPER HUSBANDRY AND A STABLE ENVIRONMENT -- 9.3 ENVIRONMENTAL VARIABLES THAT CAN BE CONTROLLED -- 9.4 DEALING WITH EMERGENCIES (E.G., POWER FAILURE, FLOODING, AIR-HANDLINGFAILURE, HEATING OR COOLING FAILURE, FIRE -- REFERENCE -- 10 Species-Specific Overview -- Outline -- 10.1 FACTORS ASSOCIATED WITH SELECTION OF ANIMALS -- 10.2 PROCUREMENT OF ANIMALS -- 10.3 CAGING -- 10.4 ENVIRONMENTAL ENRICHMENT -- 10.5 FOOD -- 10.6 WATER -- 10.7 HANDLING AND RESTRAINT -- 10.8 IDENTIFICATION AND RECORDS -- 10.9 ANIMAL HEALTH -- 10.10 ZOONOSES (DESCRIBE SIGNS AND SYMPTOMS IN ANIMALS AND HUMANS). 327 $a10.11 SPECIFIC TECHNIQUES: HANDS-ON TRAINING IN TECHNIQUES SUCH AS BLOOD WITHDRAWAL, INJECTIONS, SPE ... -- REFERENCES -- IV RESOURCES -- 1 Sources of Information -- ANIMAL WELFARE INFORMATION CENTER -- NATIONAL LIBRARY OF MEDICINE -- INSTITUTE OF LABORATORY ANIMAL RESOURCES -- FOUNDATION FOR BIOMEDICAL RESEARCH -- CENTER FOR ALTERNATIVES -- CENTER FOR ANIMALS AND PUBLIC POLICY -- 2 Selected Bibliography -- LAWS, POLICIES, AND GUIDELINES -- ETHICS, ANIMAL WELFARE, AND THE USE OF ANIMALS IN BIOMEDICAL RESEARCH, EDUCATION, AND TESTING -- ALTERNATIVES -- INSTITUTIONAL ANIMAL CARE AND USE COMMITTEES -- RECOGNITION AND ALLEVIATION OF PAIN AND DISTRESS -- SURGERY -- EUTHANASIA -- BIOLOGY, HUSBANDRY, AND CARE -- General References (Concerning More than one Species or Subject) -- Species-Specific References -- Carnivores -- Domestic Animals -- Nonhuman Primates -- Rabbits -- Rodents -- Other Animals -- GENETICS AND NOMENCLATURE -- NUTRITION -- OCCUPATIONAL HAZARDS AND LABORATORY SAFETY -- PATHOLOGY AND THERAPY -- General References -- Species-Specific References -- Carnivores -- Domestic Animals -- Fishes -- Nonhuman Primates -- Rabbits and Rodents -- OTHER ANIMALS -- DESIGN OF EDUCATIONAL COURSES -- 3 Audiovisual Materials -- V HOW TO DEVELOP, DELIVER, AND EVALUATE AN EDUCATIONAL PROGRAM -- 1 How to Approach the Task of Education -- EDUCATIONAL GOALS -- SETTING OBJECTIVES -- SELECTING METHODS -- Lectures/Seminars -- Interactive Sessions -- Workshops/Laboratories -- Individualized Study -- Self Assessment -- OVERCOMING RESISTANCE TO CHANGE -- CONCLUSIONS -- 2 How to Plan and Implement a Training Course -- IDENTIFYING THE TARGET AUDIENCE -- ALLOCATING A BUDGET/FUNDING -- DETERMINING GOALS AND OBJECTIVES -- SCHEDULING THE COURSE -- RESERVING FACILITIES -- IDENTIFYING AND CONTACTING LECTURERS -- OBTAINING AND REVIEWING AUDIOVISUAL MATERIALS. 327 $aASSEMBLING REFERENCE MATERIALS -- PUBLICIZING THE COURSE -- REFERENCES -- 3 Evaluation -- EVALUATING THE INSTITUTIONAL PROGRAM -- EVALUATING THE COURSE -- REFERENCE -- Appendixes -- I Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training -- II The Animal Welfare Information Center -- ANIMAL WELFARE INFORMATION CENTER ESTABLISHED -- SERVICES AND INFORMATION RESOURCES AVAILABLE THROUGH AWIC -- AWIC REFERENCE PUBLICATIONS -- PROJECTS SUPPORTED BY AWIC -- UPDATES REGARDING AWIC AND NAL -- PUBLICATIONS AVAILABLE THROUGH AWIC -- III Sample Objectives or Self-Assessment Statements -- INTRODUCTION -- CORE MODULE -- Laws, Regulations, and Policies That Impact on the Care and Use of Animals -- Ethical and Scientific Issues -- Alternatives -- Responsibilities of the Institution, Animal Care and Use Committee, and Research and Veterinary Staffs -- Pain and Distress -- Anesthetics, Analgesics, Tranquilizers, and Neuromuscular Blocking Agents -- Survival Surgical and Postsurgical Care -- Euthanasia -- Husbandry, Care, and the Importance of the Environment -- Resources -- SPECIES-SPECIFIC MODULE -- Selection and Procurement of Animals -- Husbandry and Care -- Animal Health -- Safety and Health Considerations (Zoonoses) -- Specific Techniques -- Euthanasia -- PAIN-MANAGEMENT MODULE -- Definitions, Mechanisms, and Assessment -- Legal and Ethical Obligations -- Alleviation of Pain or Distress -- Anesthestics -- Euthanasia -- SURGERY MODULE -- Legal Requirements for Survival Surgery -- Aseptic Technique -- Selection and Administration of Anesthetic -- Animal Monitoring -- Surgical Techniques -- Postsurgical Care -- Medical Records -- Terminal Surgeries. 330 $aGuidelines and resources for instituting the training required by federal law. 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