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040   $aDip.to Matematica$beng
100 1 $aGoodman, Roe$043204
245 10$aSymmetry, representations, and Invariants$h[e-book] /$cby Roe Goodman, Nolan R. Wallach
260   $aNew York, NY :$bSpringer,$c2009
300   $bv.: digital
440  0$aGraduate texts in mathematics,$x0072-5285 ;$v255
650  0$aAlgebra
650  0$aGroup theory
650  0$aMathematical physics
650  0$aTopological Groups
700 1 $aWallach, Nolan R.
773 0 $aSpringer eBooks
856 40$uhttp://dx.doi.org/10.1007/978-0-387-79852-3$zAn electronic book accessible through the World Wide Web
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996   $aSymmetry, representations, and Invariants$9229957
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100   $a20101215h20102010  uy         0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aRare diseases and orphan products $eaccelerating research and development /$fCommittee on Accelerating Rare Diseases Research and Orphan Product Development, Board on Health Sciences Policy ; Marilyn J. Field and Thomas F. Boat, editors ; Institute of Medicine of the National Academies
205   $a1st ed.
210  1$aWashington, D.C. :$cNational Academies Press,$d2010.
210  4$dİ2010
215   $a1 online resource (xxi, 420 pages) $cillustrations
300   $aDescription based upon print version of record.
311 0 $a9780309158060 
311 0 $a0309158060 
320   $aIncludes bibliographical references (p. 249-282) and index.
327   $a""Front Matter""; ""Acknowledgments""; ""Reviewers""; ""Preface""; ""Contents""; ""Boxes, Figures, and Tables""; ""Summary""; ""1 Introduction""; ""2 Profile of Rare Diseases""; ""3 Regulatory Framework for Drugs for Rare Diseases""; ""4 Discovery Research for Rare Diseases and Orphan Product Development""; ""5 Development of New Therapeutic Drugs and Biologics for Rare Diseases""; ""6 Coverage and Reimbursement: Incentives and Disincentives for Product Development""; ""7 Medical Devices: Research and Development for Rare Diseases""
327   $a""8 Toward an Integrated Approach to Accelerating Research and Product Development for Rare Diseases""; ""References""; ""Appendix A: Study Activities""; ""Appendix B: Innovation and the Orphan Drug Act, 1983-2009: Regulatory and Clinical Characteristics of Approved Orphan Drugs""; ""Appendix C: Medicare Part D Coverage and Reimbursement of Orphan Drugs""; ""Appendix D: Glossary, Abbreviations, and Public Laws""; ""Appendix E: Rare Diseases Clinical Research Network""; ""Appendix F: Advocacy Group Approaches to Accelerating Research and Product Development: Illustrative Examples""; ""Appendix G: Committee and Staff Biographies""; ""Index""
606   $aOrphan drugs
606   $aDrugs$xDesign
606   $aRare diseases$xTreatment
615  0$aOrphan drugs.
615  0$aDrugs$xDesign.
615  0$aRare diseases$xTreatment.
676   $a615.19
701   $aField$b Marilyn J$g(Marilyn Jane)$01804195
701   $aBoat$b Thomas F$01803632
712 02$aInstitute of Medicine (U.S.).$bCommittee on Accelerating Rare Diseases Research and Orphan Product Development.
712 02$aNational Academies Press (U.S.)
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906   $aBOOK
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996   $aRare diseases and orphan products$94358436
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