LEADER 04177nam 2200673Ia 450 001 9910960099803321 005 20251017110152.0 010 $a9786610185153 010 $a9781280185151 010 $a1280185155 010 $a9780309511841 010 $a0309511844 035 $a(CKB)110986584753242 035 $a(OCoLC)52786961 035 $a(CaPaEBR)ebrary10032421 035 $a(SSID)ssj0000123215 035 $a(PQKBManifestationID)11141224 035 $a(PQKBTitleCode)TC0000123215 035 $a(PQKBWorkID)10007839 035 $a(PQKB)10404724 035 $a(MiAaPQ)EBC3375222 035 $a(Au-PeEL)EBL3375222 035 $a(CaPaEBR)ebr10032421 035 $a(OCoLC)923255209 035 $a(Perlego)4734206 035 $a(DNLM)1095734 035 $a(BIP)7081666 035 $a(EXLCZ)99110986584753242 100 $a20010511d2001 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClearing the smoke $eassessing the science base for tobacco harm reduction /$fKathleen Stratton ... [et al.], editors 205 $a1st ed. 210 $aWashington, D.C. $cInstitute of Medicine, National Academy Press$dc2001 215 $a1 online resource (656 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780309072823 311 08$a0309072824 320 $aIncludes bibliographical references and index. 327 $aFront Matter -- Preface -- REVIEWERS -- Contents -- Executive Summary -- 1 Introduction -- 2 Principles of Harm Reduction -- 3 Historical Perspective and Lessons Learned -- 4 Products for Tobacco Exposure Reduction -- 5 The Scientific Basis for PREP Assessment -- 6 Surveillance for the Health and Behavioral Consequences of Exposure Reduction -- 7 Implementation of a Science-Based Policy of Harm Reduction -- 8 Principal Conclusions -- 9 Nicotine Pharmacology -- 10 Tobacco Smoke and Toxicology -- 11 Exposure and Biomarker Assessment in Humans -- 12 Cancer -- 13 Cardiovascular Disease -- 14 Nonneoplastic Respiratory Diseases -- 15 Reproductive and Developmental Effects -- 16 Other Health Effects -- A Presentations and Submissions -- B Committee Biographical Sketches -- C Time Line of Tobacco Events -- Index. 330 $aDespite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects. Clearing the Smoke addresses the problems in evaluating whether such products actually do reduce the health risks of tobacco use. Within the context of regulating such products, the committee explores key questions: Does the use of such products decrease exposure to harmful substances in tobacco? Is decreased exposure associated with decreased harm to health? Are there surrogate indicators of harm that could be measured quickly enough for regulation of these products? What are the public health implications? This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects. With an attitude of healthy skepticism, Clearing the Smoke will be important to health policy makers, public health officials, medical practitioners, manufacturers and marketers of "reduced-harm" tobacco products, and anyone trying to sort through product claims. 606 $aSmoking$xHealth aspects 606 $aSmoking cessation 606 $aTobacco use$xPrevention 615 0$aSmoking$xHealth aspects. 615 0$aSmoking cessation. 615 0$aTobacco use$xPrevention. 676 $a362.29/66 701 $aStratton$b Kathleen R$01797964 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910960099803321 996 $aClearing the smoke$94354641 997 $aUNINA