LEADER 02635nam 2200601 a 450 001 9910959755203321 005 20251117091625.0 010 $a1-61668-374-0 035 $a(CKB)2550000000059365 035 $a(EBL)3020247 035 $a(SSID)ssj0000568957 035 $a(PQKBManifestationID)12273075 035 $a(PQKBTitleCode)TC0000568957 035 $a(PQKBWorkID)10536657 035 $a(PQKB)11368720 035 $a(MiAaPQ)EBC3020247 035 $a(Au-PeEL)EBL3020247 035 $a(CaPaEBR)ebr10676408 035 $a(OCoLC)923663273 035 $a(BIP)28923359 035 $a(EXLCZ)992550000000059365 100 $a20100114d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDiscrete optimization for TSP-like genome mapping problems /$fD. Mester ... [et al.] 205 $a1st ed. 210 $aNew York $cNova Science Publishers, Inc.$dc2010 215 $a1 online resource (74 p.) 225 1 $aGenetics--research and issues 225 1 $aNovinka 300 $a"Nova biomedical"--cover. 311 08$a1-61668-170-5 320 $aIncludes bibliographical references (p. [53]-58) and index. 327 $aGuided evolution strategy algorithm for classic TSP as a basis for solving the genetic/genomic TSP-like problems -- Multilocus genetic mapping -- Multilocus consensus genetic mapping : formulation, model and algorithms -- TSP-like problem in physical mapping (PMP). 330 $aThis book introduces a discrete optimization technique in four applications: classic Traveler Salesperson Problem (TSP), Multilocus Genetic Mapping, Multilocus Consensus Genetic Mapping, and Physical Mapping. Each of the four sections contains the problem formulation, description of the algorithm, and experimental results. The foregoing problems are solved on the basis of Guided Evolution Strategy (GES) algorithm. The algorithm was implemented in MultiPoint package (http: //multiqtl.com). The developed analytical tools were applied in many genome mapping projects. 410 0$aGenetics--research and issues series. 410 0$aNovinka (Series) 606 $aGene mapping$xMathematical models 606 $aMathematical optimization 615 0$aGene mapping$xMathematical models. 615 0$aMathematical optimization. 676 $a572.8/633 701 $aMester$b D$g(David)$01866189 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910959755203321 996 $aDiscrete optimization for TSP-like genome mapping problems$94473541 997 $aUNINA