LEADER 05589nam 2200769Ia 450 001 9910958371703321 005 20251017110056.0 010 $a9786610184187 010 $a9780309170376 010 $a0309170370 010 $a9781280184185 010 $a1280184183 010 $a9780309565738 010 $a0309565731 035 $a(CKB)111069351124296 035 $a(OCoLC)57005524 035 $a(CaPaEBR)ebrary10068398 035 $a(SSID)ssj0000176888 035 $a(PQKBManifestationID)11170154 035 $a(PQKBTitleCode)TC0000176888 035 $a(PQKBWorkID)10206980 035 $a(PQKB)10900597 035 $a(MiAaPQ)EBC3377165 035 $a(Au-PeEL)EBL3377165 035 $a(CaPaEBR)ebr10068398 035 $a(OCoLC)923268733 035 $a(Perlego)4736287 035 $a(DNLM)1134683 035 $a(BIP)9022916 035 $a(EXLCZ)99111069351124296 100 $a20040120d2001 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aImmunization safety review $ethimerosal-containing vaccines and neurodevelopmental disorders /$fKathleen Stratton, Alicia Gable, and Marie C. McCormick, editors ; Immunization Safety Review Committee, Board on Health Promotion and Disease Prevention, Institute of Medicine 205 $a1st ed. 210 $aWashington, D.C. ;$a[Great Britain] $cNational Academy Press$dc2001 215 $a1 online resource (136 p.) 225 1 $aThe Compass series 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780309076364 311 08$a0309076366 320 $aIncludes bibliographical references. 327 $aIMMUNIZATION SAFETY REVIEW -- Copyright -- Acknowledgments -- Contents -- Executive Summary -- PLAUSIBILITY ASSESSMENT -- Biological Plausibility -- Causality -- SIGNIFICANCE ASSESSMENT -- PUBLIC HEALTH RESPONSE -- Policy Review and Analysis -- Public Health and Biomedical Research -- Epidemiological Research -- Clinical Research -- Basic Science Research -- Communications -- SUMMARY -- REFERENCES -- Immunization Safety Review: Thimerosal-Containing Vaccines and Neurodevelopmental Disorders -- ORIGINS OF THE IMMUNIZATION SAFETY REVIEW PROJECT -- THE CHARGE TO THE COMMITTEE -- THE STUDY PROCESS -- THE FRAMEWORK FOR ASSESSING CAUSALITY -- UNDER REVIEW: THIMEROSAL-CONTAINING VACCINES AND NEURODEVELOPMENTAL DISORDERS -- Thimerosal in Vaccines -- Neurodevelopmental Disorders -- Autism -- Attention Deficit/Hyperactivity Disorder (ADHD) -- Speech or Language Delay -- PLAUSIBILITY ASSESSMENT -- Evidence Regarding Association: Biological Plausibility -- Mercury Toxicokinetics -- Comparisons of Ethylmercury and Methylmercury -- Health Effects of High-Dose Exposures to Thimerosal, Ethylmercury, and Methylmercury -- Health Effects of Low-Dose Exposures to Thimerosal and Methylmercury -- Investigations Related to Mercury and Heavy Metals in Children with Autism -- Application of Methylmercury Exposure Guidelines to Thimerosal Exposure from Vaccines -- Biological Plausibility Argument -- Evidence Regarding Association: Case Reports, Case Series, and Uncontrolled and Controlled Epidemiological Studies -- Case Reports and Case Series -- Epidemiological Studies -- CAUSALITY ARGUMENT -- SIGNIFICANCE ASSESSMENT -- Concern Regarding Neurodevelopmental Disorders -- Continued Exposure to Thimerosal -- Use of Thimerosal-Containing Vaccines in Other Countries -- Confusion from Changes in Hepatitis B Immunization Policy -- Trust in the Safety of Vaccines -- Conclusion. 327 $aRECOMMENDATIONS REGARDING THE PUBLIC HEALTH RESPONSE -- Policy Review and Analysis -- Public Health and Biomedical Research -- Epidemiological Studies -- Clinical Studies -- Basic Science Studies -- Communications -- SUMMARY -- REFERENCES -- Appendix A Immunization Safety Review: Measles-Mumps-Rubella Vaccine and Autism Executive Summary -- OVERVIEW OF THE IMMUNIZATION SAFETY REVIEW PROJECT -- THE HYPOTHESIZED RELATIONSHIP BETWEEN MMR AND AUTISM -- PLAUSIBILITY ASSESSMENT -- SIGNIFICANCE ASSESSMENT -- RECOMMENDATIONS -- Public Health Response -- Policy Review -- Research Regarding MMR and ASD -- Communications -- General and Crosscutting Issues -- SUMMARY -- REFERENCES -- Appendix B Monday, July 16, 2001 Meeting Agenda -- Appendix C Thimerosal Content in Licensed Vaccines -- Appendix D Immunization Safety Review Committee Biosketches -- Board on Health Promotion Disease Prevention Liaison. 330 $aIn this report, the Immunization Safety Review committee examines the hypothesis of whether or not the use of vaccines containing the preservative thimerosal can cause neurodevelopmental disorders (NDDs), specifically autism, attention deficit/hyperactivity disorder (ADHD), and speech or language delay. 410 0$aCompass series (Washington, D.C.) 606 $aVaccination$xComplications 606 $aDevelopmental disabilities$xEtiology 606 $aOrganomercury compounds$xToxicology 615 0$aVaccination$xComplications. 615 0$aDevelopmental disabilities$xEtiology. 615 0$aOrganomercury compounds$xToxicology. 676 $a614.593 701 $aStratton$b Kathleen R$01797964 701 $aGable$b Alicia$01807147 701 $aMcCormick$b Marie C$01806833 712 02$aInstitute of Medicine (U.S.).$bImmunization Safety Review Committee. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910958371703321 996 $aImmunization safety review$94369128 997 $aUNINA