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100   $a20040223d2004      uy         0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 00$aBiological confinement of genetically engineered organisms /$fCommittee on Biological Confinement of Genetically Engineered Organisms, Board on Agriculture and Natural Resources, Board on Life Sciences, Division on Earth and Life Studies
205   $a1st ed.
210   $aWashington, DC $cNational Academies Press$dc2004
215   $a1 online resource (276 p.)
300   $aDescription based upon print version of record.
311 08$a9780309090858 
311 08$a0309090857 
320   $aIncludes bibliographical references (p. 199-234) and index.
327   $a""Front Matter""; ""Acknowledgments""; ""Preface""; ""Contents""; ""Tables, Figures, and Boxes""; ""Executive Summary""; ""1 Introduction""; ""2 When and Why to Consider Bioconfinement""; ""3 Bioconfinement of Plants""; ""4 Bioconfinement of Animals: Fish, Shellfish, and Insects""; ""5 Bioconfinement of Viruses, Bacteria, and Other Microbes""; ""6 Biological and Operational Considerations for Bioconfinement""; ""References""; ""About the Authors""; ""Board on Agriculture and Natural Resources Publications""; ""Index""
330   $aGenetically engineered organisms (GEOs) have been under development for more than 20 years while GE crops have been grown commercially during the last decade. During this time, a number of questions have cropped up concerning the potential consequences that certain GEOs might have on natural or managed ecosystems and human health. Interest in developing methods to confine some GEOs and their transgenes to specifically designated release settings has increased and the success of these efforts could facilitate the continued growth and development of this technology. Biological Confinement of Genetically Engineered Organisms examines biological methods that may be used with genetically engineered plants, animals, microbes, and fungi. Bioconfinement methods have been applied successfully to a few non-engineered organisms, but many promising techniques remain in the conceptual and experimental stages of development. This book reviews and evaluates these methods, discusses when and why to consider their use, and assesses how effectively they offer a significant reduction of the risks engineered organisms can present to the environment. Interdisciplinary research to develop new confinement methods could find ways to minimize the potential for unintended effects on human health and the environment. Need for this type of research is clear and successful methods could prove helpful in promoting regulatory approval for commercialization of future genetically engineered organisms.
606   $aTransgenic organisms$xSafety measures
606   $aConfinement farms
606   $aAgricultural biotechnology
606   $aInfertility in animals
606   $aTransgenic organisms$xRisk assessment
615  0$aTransgenic organisms$xSafety measures.
615  0$aConfinement farms.
615  0$aAgricultural biotechnology.
615  0$aInfertility in animals.
615  0$aTransgenic organisms$xRisk assessment.
676   $a577/.18
712 02$aNational Research Council (U.S.).$bCommittee on Biological Confinement of Genetically Engineered Organisms.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910957497903321
996   $aBiological confinement of genetically engineered organisms$94364550
997   $aUNINA