LEADER 03453nam 2200661Ia 450 001 9910957224803321 005 20251116233311.0 010 $a9780300189551 010 $a0300189559 024 7 $a10.12987/9780300189551 035 $a(CKB)2560000000102340 035 $a(EBL)3421237 035 $a(SSID)ssj0000892588 035 $a(PQKBManifestationID)12401245 035 $a(PQKBTitleCode)TC0000892588 035 $a(PQKBWorkID)10897708 035 $a(PQKB)10381331 035 $a(StDuBDS)EDZ0000157963 035 $a(MiAaPQ)EBC3421237 035 $a(DE-B1597)485765 035 $a(OCoLC)849928778 035 $a(DE-B1597)9780300189551 035 $a(Au-PeEL)EBL3421237 035 $a(CaPaEBR)ebr10718693 035 $a(CaONFJC)MIL496066 035 $a(OCoLC)923603850 035 $a(Perlego)1089144 035 $z(OCoLC)849928778 035 $a(EXLCZ)992560000000102340 100 $a20121107d2013 uy 0 101 0 $aeng 135 $aur|nu---|u||u 181 $ctxt 182 $cc 183 $acr 200 10$aRisk, chance, and causation $einvestigating the origins and treatment of disease /$fMichael B. Bracken 205 $a1st ed. 210 $aNew Haven $cYale University Press$dc2013 215 $a1 online resource (288 p.) 300 $aDescription based upon print version of record. 311 0 $a9780300188844 311 0 $a0300188846 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tContents --$tAcknowledgments --$tAbbreviations --$tOne. Risk, Chance, and Causation --$tTwo. Chance and Randomness --$tThree. Risk --$tFour. Randomization and Clinical Trials --$tFive. More Trials and Some Tribulations --$tSix. Harm --$tSeven. Screening, Diagnosis, and Prognosis --$tEight. A Statistical Sojourn --$tNine. Disease Clusters --$tTen. Genetics and the Genome --$tEleven. The Study of Mankind Is Man --$tTwelve. Celebrity Trumps Science --$tThirteen. Replication and Pooling --$tFourteen. Bias in Publication and Reporting --$tFifteen. Causes --$tSixteen. Ultimate Causation --$tNotes --$tBibliography and Further Reading --$tIndex 330 $aThe press and other media constantly report news stories about dangerous chemicals in the environment, miracle cures, the safety of therapeutic treatments, and potential cancer-causing agents. But what exactly is actually meant by "increased risk"-should we worry if we are told that we are at twice the risk of developing an illness? And how do we interpret "reduced risk" to properly assess the benefits of noisily touted dietary supplements? Demonstrating the difficulty of separating the hype from the hypothesis, noted epidemiologist Michael Bracken clearly communicates how clinical epidemiology works. Using everyday terms, Bracken describes how professional scientists approach questions of disease causation and therapeutic efficacy to provide readers with the tools to help them understand whether warnings of environmental risk are truly warranted, or if claims of therapeutic benefit are justified. 606 $aEpidemiology 606 $aTherapeutics 615 0$aEpidemiology. 615 0$aTherapeutics. 676 $a616.07/1 700 $aBracken$b Michael B.$f1942-$01809649 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910957224803321 996 $aRisk, chance, and causation$94360554 997 $aUNINA