LEADER 03367nam 2200613Ia 450 001 9910956821703321 005 20251116181633.0 010 $a1-61122-395-4 035 $a(CKB)2550000001041640 035 $a(EBL)3018767 035 $a(SSID)ssj0000836272 035 $a(PQKBManifestationID)11457668 035 $a(PQKBTitleCode)TC0000836272 035 $a(PQKBWorkID)11007785 035 $a(PQKB)11195329 035 $a(MiAaPQ)EBC3018767 035 $a(Au-PeEL)EBL3018767 035 $a(CaPaEBR)ebr10661705 035 $a(OCoLC)831664507 035 $a(BIP)32205590 035 $a(EXLCZ)992550000001041640 100 $a20100823d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTumor suppressors /$fSusan D. Nguyen, editor 205 $a1st ed. 210 $aNew York $cNova Science Publishers$dc2011 215 $a1 online resource (294 p.) 225 1 $aCell biology research progress 225 1 $aCancer etiology, diagnosis and treatments 300 $aDescription based upon print version of record. 311 08$a1-61761-986-8 320 $aIncludes bibliographical references and index. 327 $aAflatoxin B1 and acetaldehyde mutational patterns in the tumour suppressor gene TP53 : experimental fingerprints using a functional assay and relevance to human cancer aetiology / Vincent Paget, Mathilde Lechevrel, Franc?ois Sichel -- Curative therapy for terminal cancer? / Doug Dix -- Breast cancer screening by methylation analysis of tumor suppressor genes in breast fluid / J.S. de Groot ... [et al.] -- Rab GTPases as potential tumor suppressors / Christelle En Lin Chua ... [et al.] -- Regulation of neutrophil function by tumor suppressor PTEN / Subhanjan Mondal, Hongbo R. Luo -- Emerging roles of BRIT1/MCPH1 in genome maintenance and tumor suppression / Guang Peng, Shiaw-Yih Lin -- 327 $aThe role of histone deacetylase (HDAC) and EZH2 in oncogenesis : epigenetic silencing of tumor suppressors / Junpei Yamaguchi, Motoko Sasaki, Yasuni Nakanuma -- Functions of Kank1 and carcinogenesis / Naoto Kakinuma ... [et al.] -- The relationship between microRNA and tumor suppressors / Douglus Wu, Mary Waye -- How does tumor suppressor FHIT modulate oxidative stress and DNA damage checkpoints in early cancer? / Hideshi Ishii, Toshiyuki Saito -- Role of the tumor suppressor PDCD4 in the differentiation of the skin / Sachiko Matsuhashi, Takeshi Okawa, Yutaka Narisawa. 330 $aA tumour suppresser gene, or anti-oncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes. This book presents topical research data in the study of tumour suppressers. 410 0$aCell biology research progress. 410 0$aCancer etiology, diagnosis, and treatments. 606 $aAntioncogenes 606 $aTumor suppressor proteins 615 0$aAntioncogenes. 615 0$aTumor suppressor proteins. 676 $a612/.01575 701 $aNguyen$b Susan D$01871451 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910956821703321 996 $aTumor suppressors$94480287 997 $aUNINA