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Indici 600 14$aCatullo, Gaio Valerio 907 $a.b14338282$b05-03-18$c05-03-18 912 $a991003468769707536 945 $aLE007 870.1 Catullus DEL 01.502$g1$i2007000286340$lle007$nLE007 2018 Pregresso$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i15837336$z05-03-18 996 $aDue studi catulliani$9550867 997 $aUNISALENTO 998 $ale007$b05-03-18$cm$da $e-$fita$git $h0$i0 LEADER 02685nam 22005415 450 001 9910659483903321 005 20250627115057.0 010 $a3-031-12801-X 024 7 $a10.1007/978-3-031-12801-1 035 $a(CKB)5710000000110540 035 $a(DE-He213)978-3-031-12801-1 035 $a(PPN)268205191 035 $a(MiAaPQ)EBC7221198 035 $a(EXLCZ)995710000000110540 100 $a20230207d2022 u| 0 101 0 $afre 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHomogénéisation en milieu périodique... ou non $eUne introduction /$fby Xavier Blanc, Claude Le Bris 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (XVIII, 488 p. 1 ill.) 225 1 $aMathématiques et Applications,$x2198-3275 ;$v88 311 08$a3-031-12800-1 327 $a1 La dimension "zéro" -- 2 Homogénéisation en dimension 1 -- 3 Dimension ? 2 : Les cas "simples" : abstrait ou périodique -- 4 Dimension ? 2 : Des cas explicites au-delà du périodique -- 5 Approches numériques -- 6 Au-delà de l'équation de diffusion et sujets variés. 330 $aCet ouvrage est une introduction pédagogique à la théorie de l?homogénéisation, et aux approches numériques associées, pour la compréhension et la simulation des problèmes à plusieurs échelles. La présentation est axée sur les différentes hypothèses possibles pour mettre en ?uvre la théorie, selon que le milieu ambiant a une géométrie périodique ou non. 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[et al.], rapporteurs ; Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2012 215 $a1 online resource (113 p.) 300 $aDescription based upon print version of record. 311 08$a0-309-22034-3 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Figures and Box""; ""Abbreviations and Acronyms""; ""1 Introduction""; ""2 The Realization of Genomic Medicine""; ""3 The Analysis of Genomic Data""; ""4 The Interpretation of Genomic Data""; ""5 The Delivery of Genomic Data""; ""6 Ethical and Legal Issues""; ""7 Workforce Development""; ""8 Envisioning the Future""; ""References""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biographical Sketches""; ""Appendix C: Registered Attendees"" 330 $aThe initial sequencing of the human genome, carried out by an international group of experts, took 13 years and $2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a consumer can have his or her entire genome sequenced by a single company in a matter of days for less than $10,000, though the addition of interpretation may extend this time frame. Given the rapid technological advances, the potential effect on the lives of patients, and the increasing use of genomic information in clinical care, it is important to address how genomics data can be integrated into the clinical setting. Genetic tests are already used to assess the risk of breast and ovarian cancers, to diagnose recessive diseases such as cystic fibrosis, to determine drug dosages based on individual patient metabolism, and to identify therapeutic options for treating lung and breast tumors, melanoma, and leukemia. With these issues in mind and considering the potential impact that genomics information can have on the prevention, diagnosis, and treatment of disease, the Roundtable on Translating Genomic-Based Research for Health hosted a workshop on July 19, 2011, to highlight and identify the challenges and opportunities in integrating large-scale genomic information into clinical practice. Integrating large-scale genomic information into clinical practice summarizes the speaker presentations and the discussions that followed them. This report focuses on several key topics, including the analysis, interpretation, and delivery of genomic information plus workforce, ethical, and legal issues. 606 $aMedical genetics$xMethodology 606 $aGenomics 606 $aGenetic disorders$xEpidemiology 615 0$aMedical genetics$xMethodology. 615 0$aGenomics. 615 0$aGenetic disorders$xEpidemiology. 676 $a572.86 701 $aOlsen$b Steven$01602366 712 02$aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910955983103321 996 $aIntegrating large-scale genomic information into clinical practice$94447005 997 $aUNINA