LEADER 02073nam 22004934a 450 001 9910955951603321 005 20251116151331.0 035 $a(CKB)1000000000031729 035 $a(OCoLC)228114416 035 $a(CaPaEBR)ebrary10084463 035 $a(SSID)ssj0000279824 035 $a(PQKBManifestationID)11223290 035 $a(PQKBTitleCode)TC0000279824 035 $a(PQKBWorkID)10268018 035 $a(PQKB)11053568 035 $a(MiAaPQ)EBC3137906 035 $a(BIP)7442085 035 $a(EXLCZ)991000000000031729 100 $a20011005d2002 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGenes & signals /$fMark Ptashne, Alexander Gann 210 $aCold Spring Harbor, New York $cCold Spring Harbor Laboratory Press$dc2002 215 $a1 online resource (209 p.) 300 $aIncludes bibliographical references and index. 311 08$a0-87969-631-1 327 $aIntro -- Contents -- Preface -- Foreword -- Introduction -- Lessons from Bacteria -- Yeast: A Single- celled Eukaryote -- Some Notes on Higher Eukaryotes -- Enzyme Specificity and Regulation -- Afterword -- More on Cooperativity -- Topogenic Sequences -- All- or- none Effects and Levels of Gene Expression -- Index. 330 $aThis text analyzes gene regulation from a different perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others. 517 3 $aGenes and signals 606 $aGenetic regulation 615 0$aGenetic regulation. 676 $a572.8/65 700 $aPtashne$b Mark$0286948 701 $aGann$b Alexander$f1954-$0286949 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910955951603321 996 $aGenes & signals$954709 997 $aUNINA