LEADER 05411nam 2200889 u 450 001 9910955289603321 005 20250226110030.0 010 $a9786610834792 010 $a9780190286040 010 $a0190286040 010 $a9780197705988 010 $a0197705987 010 $a9781280834790 010 $a128083479X 010 $a9780199771646 010 $a0199771642 024 7 $a10.1093/oso/9780195139068.001.0001 035 $a(CKB)2450000000001837 035 $a(EBL)4704279 035 $a(SSID)ssj0000291758 035 $a(PQKBManifestationID)12105927 035 $a(PQKBTitleCode)TC0000291758 035 $a(PQKBWorkID)10256225 035 $a(PQKB)11102655 035 $a(Au-PeEL)EBL4704279 035 $a(CaPaEBR)ebr11273965 035 $a(OCoLC)960165978 035 $a(Au-PeEL)EBL4963034 035 $a(CaONFJC)MIL83479 035 $a(OCoLC)1027176181 035 $a(OCoLC)1406787028 035 $a(StDuBDS)9780197705988 035 $a(MiAaPQ)EBC4704279 035 $a(MiAaPQ)EBC4963034 035 $a(MiAaPQ)EBC31914710 035 $a(EXLCZ)992450000000001837 100 $a20020930e20232002 |y | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCleft lip and palate $efrom origin to treatment /$fedited by Diego F. Wyszynski 205 $a1st ed. 210 1$aOxford :$cOxford University Press,$d2023. 215 $a1 online resource (547 p.) 225 1 $aOxford scholarship online 300 $aPreviously issued in print: 2002. 311 08$a9780195139068 311 08$a0195139062 320 $aIncludes bibliographical references and index. 327 $aContents; Contributors; SECTION I: BASIC PRINCIPLES; Part I: Basic Embryology of Cleft Lip and Palate; 1. Formation of the Primary Palate; 2. Palatogenesis: Closure of the Secondary Palate; 3. Genes Implicated in Lip and Palate Development; Part II: Clinical Features of Cleft Lip and Palate; 4. The Orofacial Examination: Normal and Abnormal Findings; 5. Classification and Description of Nonsyndromic Clefts; 6. Syndromes with Orofacial Clefting; 7. Morphometric Characteristics of Subjects with Oral Facial Clefts and Their Relatives 327 $a8. Craniofacial Morphology and Growth in Infants and Young Children with Cleft Lip and PalatePart III: Epidemiology of Cleft Lip and Palate; 9. Methodological Issues in Epidemiological Studies of Oral Clefts; 10. Exposure Assessment in Studies of Oral Clefts; 11. Birth Defects Surveillance Systems and Oral Clefts; 12. Epidemiology of Oral Clefts: An International Perspective; 13. Environmental Risk Factors and Oral Clefts; 14. Maternal Nutrition and Oral Clefts; 15. Experimental Models for the Study of Oral Clefts; Part IV: Genetics of Cleft Lip and Palate; 16. The Human Genome Project 327 $a17. Twin Studies in Oral Cleft Research18. Segregation Analyses; 19. Mode of Inheritance of Oral Clefts; 20. Association Studies; 21. Locating Genes for Oral Clefts in Humans; 22. Mapping Studies in Animal Models; 23. Gene-Environment Interaction and Risk to Oral Clefts; SECTION II: TREATMENT; 24. Developing a Cleft Palate or Craniofacial Team; 25. Health Care for Children with Cleft Lip and Palate: Comprehensive Services and Infant Feeding; 26. Staging of Cleft Lip and Palate Reconstruction: Infancy through Adolescence 327 $a27. Evaluation and Management of Speech, Language, and Articulation Disorders28. Pediatric Dental Care; 29. Role of the Orthodontist in the Management of Patients with Cleft Lip and/or Palate; 30. Otolaryngologic Needs of Individuals with Oral Clefts; 31. Genetic Counseling and Interpretation of Risk Figures; 32. Psychological Care of Children with Cleft Lip and Palate in the Family; 33. International Surgical Missions; 34. Evidence-Based Care for Children with Cleft Lip and Palate; SECTION III: PUBLIC HEALTH ISSUES 327 $a35. Prevention of Oral Clefts through the Use of Folic Acid and Multivitamin Supplements: Evidence and Gaps36. Costs of Cleft Lip and Palate: Personal and Societal Implications; 37. Insurance and Coverage of Care; 38. Parents' Perspective on Cleft Lip and Palate; 39. Ethical Issues in the Care of Children with Craniofacial Conditions; 40. Translating Research Findings into Public Health Action and Policy; 41. Educating the Practitioner and the Public; 42. Innovations in International Cooperation for Patients with Cleft Lip and Palate; Appendix: Directory of Internet Resources; Glossary; A; B 327 $aC 330 8 $aThe authors describe the embryological and molecular mechanisms of cleft causation, present and illustrate the genetic and epidemiological methods used to identify risk factors for oral clefts, and describe treatments by the various professionals of the cleft team. 410 0$aOxford scholarship online. 606 $aCleft lip 606 $aCleft lip$xSurgery 606 $aCleft palate 606 $aCleft palate$xSurgery 615 0$aCleft lip. 615 0$aCleft lip$xSurgery. 615 0$aCleft palate. 615 0$aCleft palate$xSurgery. 676 $a617.522 702 $aWyszynski$b Diego F. 801 0$bStDuBDS 801 2$bUk 801 2$bStDuBDSZ 801 2$bStDuBDSZ 906 $aBOOK 912 $a9910955289603321 996 $aCleft lip and palate$94322135 997 $aUNINA