LEADER 02938oam 22005173 450 001 9910954993803321 005 20240405202613.0 035 $a(CKB)3710000000358075 035 $a(MiAaPQ)EBC1968700 035 $a(EXLCZ)993710000000358075 100 $a20231204d2009 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEsophageal Pain 205 $a1st ed. 210 1$aSan Diego :$cPlural Publishing, Incorporated,$d2009. 210 4$d©2010. 215 $a1 online resource (212 pages) 311 08$a1-59756-337-4 327 $aHeartburn and esophageal pain : scope of the problem / John Dent -- Functional heartburn : what is it? / Ronnie Fass -- Nature of esophageal pain receptors / Amanda J. Page and Ashley Blackshaw -- Vagal and spinal distension sensitive primary afferents of the esophagus : implications for visceral nociceptors / Raj K. Goyal -- The esophageal mucosa and heartburn / Roy C. Orlando -- Neutral reflux (weakly acid) in typical and atypical GERD symptoms / Daniel Sifrim -- Longitudinal muscle contraction, TLESR, reflux & pain / Ravinder Mittal -- Biomechanics of sensation / Hans Gregersen and Asbjørn Mohr Drewes -- Molecular pathways and their sensitization / Pankaj Jay Pasricha -- Cortical processing of esophageal pain / Adeyemi Lawal and Reza Shaker -- Esophageal hypersensitivity : is it peripheral or central? / A. Sharma and Qasim Aziz -- Diagnostic strategy for esophageal pain / Peter J. Kahrilas -- How to treat esophageal chest pain / Satish S.C. Rao -- New drugs on the horizon for the treatment of esophageal pain / Anders Lehmann. 330 $aThis book provides in-depth coverage of all aspects of esophageal pain. Chapters cover the scope of the problem; basic science with regards to the nature of neural pathways, receptors involved in sensing pain and the role of central nervous system in sensing the pain; different stimuli responsible for the genesis of esophageal pain, including the role of acid, muscle spasm and reflux; hypersensitivity of pain receptors, spinal nerves and central nervous system; and the state of the art in diagnosis and treatment strategies. 606 $aHeartburn 606 $aEsophagus$xPathophysiology 606 $aEsophagus$xInnervation 606 $aEsophagus$xphysiopathology 606 $aHeartburn 606 $aPain 615 0$aHeartburn. 615 0$aEsophagus$xPathophysiology. 615 0$aEsophagus$xInnervation. 615 12$aEsophagus$xphysiopathology. 615 12$aHeartburn. 615 22$aPain. 676 $a616.3/24 700 $aPlural Publishing$b Incorporated$01825943 701 $aMittal$b Ravinder K$01825944 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910954993803321 996 $aEsophageal Pain$94393892 997 $aUNINA