LEADER 03566nam 2200625Ia 450 001 9910954839603321 005 20251116221328.0 010 $a1-61209-855-X 035 $a(CKB)2560000000070414 035 $a(EBL)3019146 035 $a(SSID)ssj0000467271 035 $a(PQKBManifestationID)12185094 035 $a(PQKBTitleCode)TC0000467271 035 $a(PQKBWorkID)10467104 035 $a(PQKB)11257527 035 $a(MiAaPQ)EBC3019146 035 $a(Au-PeEL)EBL3019146 035 $a(CaPaEBR)ebr10662953 035 $a(OCoLC)699507770 035 $a(BIP)28674017 035 $a(EXLCZ)992560000000070414 100 $a20091216d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiodegradable composites for bone regeneration /$fLuigi Calandrelli, Paola Laurienzo, and Adriana Oliva 205 $a1st ed. 210 $aNew York $cNova Science Publishers$dc2010 215 $a1 online resource (82 p.) 225 1 $aBiomaterials--properties, production and devices series 300 $aDescription based upon print version of record. 311 08$a1-60876-957-7 320 $aIncludes bibliographical references (p. [52]-64) and index. 327 $aPrinciples of tissue engineering --- Biocompatibility testing of medical devices: "tests for in vitro cytotoxicity (EN ISO 10993-5)" -- Principles of synthetic bone substitutes -- Polymers for bone tissue engineering -- Silica-based materials and nanoparticles for bone regeneration -- The use of calcium sulphate in bone regeneration -- Realization and performance analysis of PCL/silica nanocomposites for bone regeneration -- Mechanical alloys (chemical physical and mechanical properties) -- Chemical modification and characterization of nanocomposites -- Morphologic analysis (SEM) : biological evaluation -- Experimental materials -- Preparation of silica nanoparticles -- Preparation of nanocomposites -- Differential thermal analysis (DSC) -- Preparation and characterization of bone marrow MSCs -- Novel injectable alginate/n-succinylchitosan/calcium sulphate composites as bone-defects : biological evaluation. 330 $aIn the present book, after briefly summarizing recent literature concerning modification and applications of these materials, several recent developments of bio-composites containing silica nanoparticles or calcium sulphate intended for bone regeneration are reported. The composites are characterized with respect to their chemical-physical and mechanical properties. Their bio-compatibility and capacity to induce the osteoblastic phenotype in human bone marrow mesenchymal stem cells have been assessed. The authors focus on two particular systems based on either natural or synthetic bio-polymers with different biofillers: alginate/chitosan blends with calcium sulphate and poly(-caprolactone) with silica nanoparticles. 410 0$aBiomaterials--properties, production, and devices series. 606 $aBone substitutes 606 $aBone regeneration 606 $aComposite materials 615 0$aBone substitutes. 615 0$aBone regeneration. 615 0$aComposite materials. 676 $a617.4/710592 700 $aCalandrelli$b Luigi$01871598 701 $aLaurienzo$b Paola$01871599 701 $aOliva$b Adriana$0619801 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910954839603321 996 $aBiodegradable composites for bone regeneration$94480483 997 $aUNINA