LEADER 04269nam 2200673Ia 450 001 9910953850403321 005 20240417001332.0 010 $a9786610214747 010 $a9781280214745 010 $a1280214740 010 $a9780309568142 010 $a0309568145 010 $a9780585143910 010 $a0585143919 035 $a(CKB)111004366658452 035 $a(OCoLC)726823183 035 $a(CaPaEBR)ebrary10071414 035 $a(MiAaPQ)EBC3377387 035 $a(Au-PeEL)EBL3377387 035 $a(CaPaEBR)ebr10071414 035 $a(CaONFJC)MIL21474 035 $a(OCoLC)923270222 035 $a(NjHacI)99111004366658452 035 $a(BIP)000162739 035 $a(Perlego)4735182 035 $a(EXLCZ)99111004366658452 100 $a19901022d1989 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBiologic markers in reproductive toxicology /$fSubcommittee on Reproductive and Neurodevelopmental Toxicology, Committee on Biologic Markers, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 1$aWashington, D.C. :$cNational Academy Press,$d1989. 215 $a1 online resource (xxi, 395 pages) $cillustrations 300 $aIncludes index. 311 0 $a9780309039796 311 0 $a0309039797 320 $aIncludes bibliography (p. 319-372) and index. 327 $aExecutive summary -- Report of the Oversight Committee. I. Biologic markers in male reproductive and gametic genetic toxicology. Introduction -- Clinical evaluation of male infertility -- Biologic markers of testicular function -- Biologic markers of epididymal structure and function -- Biologic markers of accessory sex organ structure and function -- Biologic markers of human male reproductive health and physiologic damage -- Assessing transmitted mutations in mice -- Markers for measuring germinal genetic toxicity and heritable mutations in people -- Conclusions and recommendations. II. Biologic markers in female reproductive toxicology. Introduction -- Biologic markers of genetic damage in females -- Biologic markers of reproductive development and aging -- Biologic markers of nonconceptive menstrual cycles -- Developing assays of biologic markers for epidemiologic studies: experience with a marker of pregnancy and early loss -- Conclusions and recommendations. III. Biologic markers of toxicity during pregnancy. Introduction -- Molecular biology: developing DNA markers of genotoxic effects -- Reproductive immunology: biologic markers of compromised pregnancies -- Cell biology: identifying biologic markers expressed during early pregnancy -- Physiologic assessment of fetal compromise -- Conclusions and Recommendations. IV. Biologic Markers in Neurodevelopmental Toxicology. Introduction -- Developmental neurobiology of the central nervous system -- Morphologic, neurochemical, and behavioral responses to toxic agents -- Methodologic issues of extrapolation from animal studies to human toxicant exposure -- Lead as a paradigm for the study of neurodevelopmental toxicology -- Conclusions and recommendations -- Appendix: Assessing the validity of biologic markers: alpha-fetoprotein -- References -- Biographies -- Index. 330 $aExamines the potential use of these markers in environmental health studies, and clarifies definitions, underlying concepts, and possible applications. Acidic paper. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com). 606 $aReproductive toxicology 606 $aBiochemical markers 615 0$aReproductive toxicology. 615 0$aBiochemical markers. 676 $a616.6/507 712 02$aDivision on Earth and Life Studies, 712 02$aCommission on Life Sciences, 712 02$aBoard on Environmental Studies and Toxicology, 712 02$aCommittee on Biologic Markers, 712 02$aSubcommittee on Reproductive and Neurodevelopmental Toxicology, 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910953850403321 996 $aBiologic markers in reproductive toxicology$94360325 997 $aUNINA LEADER 03715nam 22006975 450 001 9910299420503321 005 20200701082441.0 010 $a81-322-2298-9 024 7 $a10.1007/978-81-322-2298-9 035 $a(CKB)3710000000437013 035 $a(EBL)2094415 035 $a(SSID)ssj0001524797 035 $a(PQKBManifestationID)11845547 035 $a(PQKBTitleCode)TC0001524797 035 $a(PQKBWorkID)11484922 035 $a(PQKB)11153491 035 $a(DE-He213)978-81-322-2298-9 035 $a(MiAaPQ)EBC2094415 035 $a(PPN)186395094 035 $a(EXLCZ)993710000000437013 100 $a20150623d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aArsenic and Fluoride Contamination$b[electronic resource] $eA Pakistan Perspective /$fby Abida Farooqi 205 $a1st ed. 2015. 210 1$aNew Delhi :$cSpringer India :$cImprint: Springer,$d2015. 215 $a1 online resource (154 p.) 300 $aDescription based upon print version of record. 311 $a81-322-2297-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $a1. Arsenic and Fluoride pollution in water and soil -- 2. Status of As and F- groundwater and soil pollution in Pakistan -- 3. Mechanism of Arsenic and Fluoride release: A case study from Lahore and Kasur, Punjab Pakistan -- 4. Case study -- 5. Sources of Pollution Discussions: Case study -- 6. Arsenic health Risk assessment -- 7. Remedies of arsenic problem and Environmental legislation in Pakistan regarding Arsenic. 330 $aThis book presents an up-to-the-minute overview of arsenic and fluoride pollution of soil and groundwater in Pakistan. It includes the author?s doctoral dissertation on Lahore as a case study and describes the mechanism of pollution on the basis of the findings in that area. The book highlights the concrete situation in Pakistan ? including the severity of the problem, its health effects and the risks posed to the people living in affected areas by these two major pollutants? and points out essential research areas that call for immediate attention. As such, it draws attention to the need for management strategies in the affected areas and offers a valuable reference work on Pakistan for students and researchers alike. 606 $aWater$xPollution 606 $aWater quality 606 $aHydrogeology 606 $aEnvironmental management 606 $aWaste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution$3https://scigraph.springernature.com/ontologies/product-market-codes/U35040 606 $aWater Quality/Water Pollution$3https://scigraph.springernature.com/ontologies/product-market-codes/212000 606 $aHydrogeology$3https://scigraph.springernature.com/ontologies/product-market-codes/G19005 606 $aEnvironmental Management$3https://scigraph.springernature.com/ontologies/product-market-codes/U17009 615 0$aWater$xPollution. 615 0$aWater quality. 615 0$aHydrogeology. 615 0$aEnvironmental management. 615 14$aWaste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution. 615 24$aWater Quality/Water Pollution. 615 24$aHydrogeology. 615 24$aEnvironmental Management. 676 $a333.7 676 $a363.7394 676 $a363.73946 676 $a551.4 676 $a628.16 700 $aFarooqi$b Abida$4aut$4http://id.loc.gov/vocabulary/relators/aut$01059263 906 $aBOOK 912 $a9910299420503321 996 $aArsenic and Fluoride Contamination$92504807 997 $aUNINA