LEADER 03563nam 22006375 450 001 9910951797903321 005 20251113202903.0 010 $a9783031771712 010 $a3031771710 024 7 $a10.1007/978-3-031-77171-2 035 $a(CKB)37391395000041 035 $a(MiAaPQ)EBC31892369 035 $a(Au-PeEL)EBL31892369 035 $a(DE-He213)978-3-031-77171-2 035 $a(OCoLC)1496394952 035 $a(EXLCZ)9937391395000041 100 $a20250126d2024 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Gut in Parkinson's Disease /$fby George Triadafilopoulos 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (212 pages) 225 0 $aMedicine Series 311 08$a9783031771705 311 08$a3031771702 327 $aIntroduction -- Parkinson?s disease (PD) - Generalities -- Parkinson?s disease (PD) and the gut - Gut PD -- Understanding the essentials of the normal gut movement and sensation -- What to watch for in gut PD: Mouth -- Pharynx and esophagus -- Small intestine -- Small intestinal bacterial overgrowth (SIBO) Colon -- Malnutrition and weight loss in PD -- Diagnostic and Assessment tools in PD -- GI symptom questionnaires in PD. 330 $aAt present, there is minimal and misleading knowledge of gastrointestinal dysfunction in Parkinson's disease among primary neurologists and gastroenterologists. This book reviews our current understanding of the GI involvement in PD, as many experiments suggest that the gut might be the site where the disease starts. Also discussed is how the gut dysfunction causes symptoms from the top (mouth) to the bottom (anal canal), and because of their frequency and severity, they contribute to disease progression and disability. In addition, the book covers the negative effects of small intestinal bacterial overgrowth (SIBO) and of a frequently silent stomach infection by Helicobacter pylori infection on the absorption of antiparkinsonian drugs, in turn causing motor fluctuations and inadequate treatment response. The Gut in Parkinson's Disease serves as a bridge between patients, their movement disorders specialists, and other health care providers who currently provide compartmentalized and at times conflicting care for such needy patients. The book distills the clinical and research experience of the author, who -as a Clinical Professor of Medicine (Gastroenterology) at Stanford University School of Medicine over the past 20 years- managed hundreds of patients with Parkinson?s Disease suffering from gut manifestations. 606 $aNeurology 606 $aNervous system$xDiseases 606 $aPrimary care (Medicine) 606 $aPatient education 606 $aNeurology 606 $aNeurological Disorders 606 $aPrimary Care Medicine 606 $aPatient Education 615 0$aNeurology. 615 0$aNervous system$xDiseases. 615 0$aPrimary care (Medicine) 615 0$aPatient education. 615 14$aNeurology. 615 24$aNeurological Disorders. 615 24$aPrimary Care Medicine. 615 24$aPatient Education. 676 $a616.8 700 $aTriadafilopoulos$b George$01815190 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910951797903321 996 $aThe Gut in Parkinson's Disease$94369928 997 $aUNINA