LEADER 00918nam0-2200301---450- 001 990009692470403321 005 20130311093905.0 010 $a92-2-203758-8 035 $a000969247 035 $aFED01000969247 035 $a(Aleph)000969247FED01 035 $a000969247 100 $a20130311d1985----km-y0itay50------ba 101 0 $afre 102 $aCH 105 $a--------001yy 200 1 $a<>coût des accidents du travail et des maladies professionnelles$fDiego Andreoni 210 $aGenève, Svizzera$cOrganisation Internationale du Travail$d1985 215 $cviii, 161 p.$d23 cm 700 1$aAndreoni,$bDiego$033845 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009692470403321 952 $aI3.156$b336$fDECTS 952 $aI3.156BS$b8520$fDECTS 959 $aDECTS 996 $aCoût des accidents du travail et des maladies professionnelles$9843268 997 $aUNINA LEADER 04444nam 22006855 450 001 9910919809503321 005 20250807153244.0 010 $a9783031659379$b(electronic bk.) 010 $z9783031659362 024 7 $a10.1007/978-3-031-65937-9 035 $a(MiAaPQ)EBC31859390 035 $a(Au-PeEL)EBL31859390 035 $a(CKB)37081493800041 035 $a(DE-He213)978-3-031-65937-9 035 $a(OCoLC)1485002310 035 $a(EXLCZ)9937081493800041 100 $a20241225d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiostatistics in Biopharmaceutical Research and Development $eClinical Trial Analysis, Volume 2 /$fedited by Ding-Geng Chen 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (522 pages) 225 0 $aMedicine Series 311 08$aPrint version: Chen, Ding-Geng Biostatistics in Biopharmaceutical Research and Development Cham : Springer,c2025 9783031659362 327 $aStatistical Challenges in the Analysis of Biomarker Data -- 2. Evaluating Predictive Accuracy of Prognostic Model for Censored Time-to-Event Data Analysis in Clinical Trials -- Statistical Methods for Accommodating Immortal Time: A Selective Review and Comparison -- Variable selection for partially functional additive Cox Model with interval-censored failure time data -- A Bayesian proportional hazards model to predict patient recruitment in multicenter clinical trials -- GET MORE INFORMATION FROM RECURRENT EVENTS DATA -- Introduction to Patient Preference Studies -- Machine Learning for Precision Medicine and Humanized AI for Future Healthcare -- The Statistical Evaluation of Surrogate Endpoints in Clinical Trials -- Treatment Effect Estimation Using Data from Observational and Non-Randomized Studies -- Methods for Comparing Two Treatments for a Dichotomous Outcome for a Two-Period Design with Treatment Switching of Control Group Period 1 Non-Responders -- Regression-based estimation of optimal adaptive treatment strategies: Key methods -- Vaccine Disease-Prevention Efficacy Studies: Traditional Approaches and New Frontiers -- Covariate Adjustment in Analyzing Randomized Clinical Trials: Approaches, Software, and Application -- Joint correlated responses and feedback effect with time-dependent covariates -- Distributions and Their Approximations for P-Values. 330 $aThe Deming Conference on Applied Statistics has long been deemed an influential event in the biostatistics and biopharmaceutical profession. It provides learning experience on recent developments in statistical methodologies in biopharmaceutical applications and FDA regulations. This book honors 80 years of contributions and dedication of the Deming Conference in biostatistics, and biopharmaceutical clinical trial methodology and applications. All chapters are contributed by world-class and prominent Deming speakers, who've contributed their cutting-edge research and developments to the community. Volume 2 covers Biomarkers in Drug Development, Time-To-Event Data Analysis and Methods, and emerging development in biopharmaceutical biostatistics. This book aims to booster research, education, and training in biostatistics and in biopharmaceutical research and development. . 606 $aStatistics 606 $aBiometry 606 $aClinical medicine$xResearch 606 $aSampling (Statistics) 606 $aPublic health 606 $aStatistics 606 $aBiostatistics 606 $aClinical Research 606 $aMethodology of Data Collection and Processing 606 $aSurvey Methodology 606 $aPublic Health 615 0$aStatistics. 615 0$aBiometry. 615 0$aClinical medicine$xResearch. 615 0$aSampling (Statistics) 615 0$aPublic health. 615 14$aStatistics. 615 24$aBiostatistics. 615 24$aClinical Research. 615 24$aMethodology of Data Collection and Processing. 615 24$aSurvey Methodology. 615 24$aPublic Health. 676 $a519.5 700 $aChen$b Ding-Geng$0767993 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910919809503321 996 $aBiostatistics in Biopharmaceutical Research and Development$94306295 997 $aUNINA