LEADER 03743nam 22006255 450 001 9910910496303321 005 20241127115249.0 010 $a9783031691881 010 $a3031691881 024 7 $a10.1007/978-3-031-69188-1 035 $a(CKB)36679504500041 035 $a(MiAaPQ)EBC31808370 035 $a(Au-PeEL)EBL31808370 035 $a(DE-He213)978-3-031-69188-1 035 $a(OCoLC)1476536508 035 $a(EXLCZ)9936679504500041 100 $a20241127d2024 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSystems Neuroscience /$fedited by Albert Cheung-Hoi Yu, Kai Gao, Jiangshan Zhan 205 $a2nd ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (260 pages) 225 1 $aAdvances in Neurobiology,$x2190-5223 ;$v41 311 08$a9783031691874 311 08$a3031691873 327 $aSection A: Principle and Molecular Foundations -- Determination of neuronal activity and its meaning for the processes of learning and memory -- Emergence of the hippocampus as a vector for goal-directed spatial navigation -- Modelling and controlling system dynamics of the brain: an intersection of machine learning and control theory -- Section B: Cutting-Edge Technologies -- Adeno-associated virus mediated gene delivery across the blood-brain barrier -- Virus-based neural circuit tracing -- Spatial omics: navigating neuroscience research into the new era -- Section C: Application and Clinical Practice -- Alzheimer's disease from modeling to mechanism research -- Inflammatory demyelinating diseases of the central nervous system -- Multi-layer analysis of RNA sequencing data in alzheimer?s disease to unravel molecular mysteries -- Opportunities for system neuroscience. 330 $aThe new edition of this popular book brings together experts in the field of Systems Neuroscience to present an overview of the area. Topics covered include how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and disease. Among the topics covered in the new edition are artificial intelligence-assisted computational neuroscience for deciphering neural networks, spatial transcriptomics single cell sequencing, and exome/whole genome sequencing for understanding brain disorders in human genetics. The best way to study the brain, the most complex organ in the body composed of 100 billion neurons with trillions of interconnections, is with a systems biology approach. 410 0$aAdvances in Neurobiology,$x2190-5223 ;$v41 606 $aNeurosciences 606 $aNeural networks (Neurobiology) 606 $aBioinformatics 606 $aNeuroscience 606 $aSystems Neuroscience 606 $aComputational and Systems Biology 615 0$aNeurosciences. 615 0$aNeural networks (Neurobiology) 615 0$aBioinformatics. 615 14$aNeuroscience. 615 24$aSystems Neuroscience. 615 24$aComputational and Systems Biology. 676 $a612.8 700 $aYu$b Albert Cheung-Hoi$01777016 701 $aGao$b Kai$01777017 701 $aZhan$b Jiangshan$01777018 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910910496303321 996 $aSystems Neuroscience$94296435 997 $aUNINA