LEADER 01218nam a2200337 i 4500 001 991000664039707536 005 20020507171945.0 008 990113s1981 us ||| | eng 020 $a0805335579 035 $ab10739944-39ule_inst 035 $aLE01300366$9ExL 040 $aDip.to Matematica$beng 082 0 $a514.2 084 $aAMS 55-01 100 1 $aGreenberg, Marvin Jay$041882 245 10$aAlgebraic topology :$ba first course /$cMarvin J. Greenberg, John R. Harper 260 $aReading, Mass :$bBenjamin/Cummings Publ.,$c1981 300 $axi, 311 p. :$bill. ;$c24 cm. 490 0 $aMathematics lecture note series ;$v58 500 $a"A revision of the first author's Lectures on algebraic topology". 500 $aErrata slip inserted. 500 $aIncludes index. 500 $aBibliography: p. 303-307 650 4$aAlgebraic topology 700 1 $aHarper, John R. 907 $a.b10739944$b23-02-17$c28-06-02 912 $a991000664039707536 945 $aLE013 55-XX GRE11 (1981)$g1$i2013000107028$lle013$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i10830789$z28-06-02 996 $aAlgebraic topology$9910947 997 $aUNISALENTO 998 $ale013$b01-01-99$cm$da $e-$feng$gus $h0$i1 LEADER 05440nam 22007695 450 001 9910908369603321 005 20241118123341.0 010 $a9783031704765$b(electronic bk.) 010 $z9783031704758 024 7 $a10.1007/978-3-031-70476-5 035 $a(MiAaPQ)EBC31786559 035 $a(Au-PeEL)EBL31786559 035 $a(CKB)36601349200041 035 $a(DE-He213)978-3-031-70476-5 035 $a(OCoLC)1472987201 035 $a(EXLCZ)9936601349200041 100 $a20241118d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiofilm Matrix /$fedited by Courtney Reichhardt 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (397 pages) 225 1 $aSpringer Series on Biofilms,$x1863-9615 ;$v13 311 08$aPrint version: Reichhardt, Courtney Biofilm Matrix Cham : Springer,c2024 9783031704758 327 $aChapter 1: The Biofilm Blueprint: Exopolysaccharide Form and Function in Bacterial Biofilms -- Chapter 2: Nucleic acids in the biofilm matrix -- Chapter 3: The Matrix Proteome: Protein Actors in the Extracellular Bacterial Biofilm.? Chapter 4: Functional amyloids as key biofilm matrix components.? Chapter 5: Structures of fibrillar adhesins that mediate bacteria-host interactions and biofilm formation.? Chapter 6: The role of matrix components in multispecies coexistence in biofilms.? Chapter 7: Cellulose and cellulose secretion in bacterial biofilms.? Chapter 8: Viscoelasticity of the biofilm matrix.? Chapter 9: Unraveling the biofilm matrix for targeted treatment strategies.? Chapter 10: Unraveling the complexity: Biofilms and their interaction with myeloid immune cell.? Chapter 11: Biofilm Dispersion and the Matrix.? Chapter 12: Experimental approaches for studying the biofilm matrix. 330 $aThis book provides a comprehensive review of biofilm matrices. The main topics include an introduction to biofilm matrices and the range of biofilm matrix components (i.e., biofilm matrixome) as well as an overview of what is known about matrix structure, functionality, and regulation. Additional topics include recent progress in investigating the biofilm matrixome as well as challenges and outstanding questions and descriptions of the influence of matrix interactions on biofilm architecture and pathogen-host interactions. This book covers an important aspect of biofilm biology-microbial biofilm matrices. Microbes form multicellular aggregates called biofilms, in which microbial cells are encased in an extracellular matrix. This enables microbes to withstand harsh environmental conditions including antibiotic treatment. Biofilms are ubiquitous in the environment and can be both beneficial and harmful. For example, they can be used to clean up wastewater, but they also cause serious and chronic infections. It is estimated that over 80% of infections in the United States are biofilm-associated. Some examples of biofilm-involved infections include infections of implanted medical devices or artificial joints and also chronic infections of burns and wounds, including diabetic ulcers. When biofilms show up during infections or human health problems, they act very differently than planktonic bacteria. For example, biofilms can be ~1000-fold more tolerant of antibiotics than their planktonic counterparts. The biofilm matrix is thought to be a key part of why these bacterial infections are so difficult to treat. Biofilm matrix composition varies between bacterial strains and under different growth conditions. In general, the biofilm matrix is rich in biopolymers and can contain exopolysaccharides, proteins, extracellular DNA (or eDNA), and lipids. The biofilm matrix promotes attachment and structurally reinforces bacterial aggregates, preventing clearance by mechanical forces. The matrix can even block antibiotics from accessing the bacteria or prevent the host immune system from seeing the bacteria. The target audience of this book is both established biofilm researchers and those who are newly learning about biofilms and biofilm matrices. 410 0$aSpringer Series on Biofilms,$x1863-9615 ;$v13 606 $aBiofilms 606 $aMicrobial populations 606 $aBacteria 606 $aMicrobiology 606 $aCytology 606 $aMicrobial ecology 606 $aBiological transport 606 $aCell membranes 606 $aBiofilms 606 $aMicrobial Communities 606 $aBacteria 606 $aCellular Microbiology 606 $aEnvironmental Microbiology 606 $aMembrane Trafficking 615 0$aBiofilms. 615 0$aMicrobial populations. 615 0$aBacteria. 615 0$aMicrobiology. 615 0$aCytology. 615 0$aMicrobial ecology. 615 0$aBiological transport. 615 0$aCell membranes. 615 14$aBiofilms. 615 24$aMicrobial Communities. 615 24$aBacteria. 615 24$aCellular Microbiology. 615 24$aEnvironmental Microbiology. 615 24$aMembrane Trafficking. 676 $a579.17 700 $aReichhardt$b Courtney$01775318 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910908369603321 996 $aBiofilm Matrix$94289926 997 $aUNINA