LEADER 02713nam  22005175  450 
001 9910896531203321
005 20241014125730.0
010   $a981-9748-64-X
024 7 $a10.1007/978-981-97-4864-8
035   $a(MiAaPQ)EBC31727240
035   $a(Au-PeEL)EBL31727240
035   $a(CKB)36358591400041
035   $a(DE-He213)978-981-97-4864-8
035   $a(EXLCZ)9936358591400041
100   $a20241014d2024      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aChemistry and Biology of O-GlcNAcylation /$fedited by Wen Yi
205   $a1st ed. 2024.
210  1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024.
215   $a1 online resource (178 pages)
311   $a981-9748-63-1 
327   $aChapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders.
330   $aO-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future.
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aCytology
606   $aBiomedical Research
606   $aCell Biology
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615  0$aCytology.
615 14$aBiomedical Research.
615 24$aCell Biology.
676   $a572.68
700   $aYi$b Wen$01766651
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910896531203321
996   $aChemistry and Biology of O-GlcNAcylation$94211318
997   $aUNINA