LEADER 01012nas 2200349 c 450 001 9910895526103321 005 20200528120416.0 035 $a(CKB)1000000000528024 035 $a(DE-599)ZDB2092280-2 035 $a(OCoLC)643939319 035 $a(DE-101)024024945 035 $a(EXLCZ)991000000000528024 100 $a20021104a19199999 |y | 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDi?ospo?ireachtai? parlaiminte$etuairisc oifigiu?il = Parliamentary debates / Da?il Eireann : official report 210 31$aDublin$d1919- 215 $aOnline-Ressource 517 1 $aParliamentary debates / Da?il Eireann$eofficial report 608 $aZeitschrift$2gnd-content 676 $a320 686 $a27$2ssgn 801 0$b0016 801 1$bDE-101 801 2$b4022 906 $aJOURNAL 912 $a9910895526103321 996 $aDi?ospo?ireachtai? parlaiminte$94258327 997 $aUNINA LEADER 04712nam 22007095 450 001 9910300227803321 005 20250609110030.0 010 $a3-319-14556-8 024 7 $a10.1007/978-3-319-14556-3 035 $a(CKB)3710000000378054 035 $a(EBL)2094284 035 $a(SSID)ssj0001465368 035 $a(PQKBManifestationID)11967627 035 $a(PQKBTitleCode)TC0001465368 035 $a(PQKBWorkID)11471542 035 $a(PQKB)11653616 035 $a(DE-He213)978-3-319-14556-3 035 $a(MiAaPQ)EBC2094284 035 $a(PPN)184888921 035 $a(MiAaPQ)EBC3108678 035 $a(EXLCZ)993710000000378054 100 $a20150319d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aArterial Disorders $eDefinition, Clinical Manifestations, Mechanisms and Therapeutic Approaches /$fedited by Adel Berbari, Giuseppe Mancia 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (426 p.) 300 $aDescription based upon print version of record. 311 08$a3-319-14555-X 320 $aIncludes bibliographical references at the end of each chapters. 327 $aPART I Introduction: Definition/Epidemiology of arterial disease -- PART II Normal structure and physiology of the arterial system -- PART III Classification of arterial pathology and clinical manifestations: Atherosclerosis -- Arteriosclerosis -- Disease of Precapillary resistance vessels -- PART IV Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors -- Metabolic factors -- Inflammatory markers -- Neurohormonal interactions -- Mineral-bone/ arterial interactions -- Endothelial function and impairment -- Miscellaneous: Pharmacologic/factors/environmental factors -- PART V Systemic arterial disorders: Arterial aging -- Diabetes mellitus -- Metabolic Syndrome/obesity -- Chronic kidney disease/Renovascular interactions -- Pulmonary Hypertension/Pulmonary vascular interactions -- Systemic  vasculitides -- Genetic/ degenerative disorders -- Hypertension -- Toxemia of pregnancy -- Kidney transplants, both donors and recipients -- PART VI Evaluation procedures: Arterial function -- Renal resistive index -- Retinal microcirculation -- PART VII Therapeutic options: Lifestyle modifications -- Pharmacologic approaches. 330 $aAs our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised. 606 $aCardiology 606 $aAngiology 606 $aNephrology 606 $aMedicine 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aAngiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33010 606 $aNephrology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33126 606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 615 0$aCardiology. 615 0$aAngiology. 615 0$aNephrology. 615 0$aMedicine. 615 14$aCardiology. 615 24$aAngiology. 615 24$aNephrology. 615 24$aBiomedicine, general. 676 $a610 676 $a616.12 676 $a616.13 676 $a616.61 702 $aBerbari$b Adel$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMancia$b Giuseppe$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300227803321 996 $aArterial Disorders$91759914 997 $aUNINA