LEADER 01826nas 2200577-a 450 001 9910893075903321 005 20240413025605.0 035 $a(DE-599)ZDB2179225-2 035 $a(CKB)991042728230250 035 $a(CONSER)--2002222855 035 $a(EXLCZ)99991042728230250 100 $a20020603a19uu9999 -a- - 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBalance of payments 210 $aValletta, Malta $cNational Statistics Office 215 $a1 online resource 225 1 $aOfficial statistics of Malta 311 08$aPrint version: Balance of payments (Valletta, Malta) 1681-7788 (DLC) 2002222855 (OCoLC)49911217 410 0$aOfficial statistics of Malta. 531 0 $aBalance of paym. 606 $aBalance of payments$zMalta$vPeriodicals 606 $aBalance of payments$zMalta$vStatistics$vPeriodicals 606 $aBalance of payments$2fast$3(OCoLC)fst00825672 606 $aZahlungsbilanzstatistik$2stw 606 $aMalta$2stw 606 $aFINANCIAL STATISTICS$2unbist 606 $aBALANCE OF PAYMENTS$2unbist 606 $aEXTERNAL DEBT$2unbist 606 $aMALTA$2unbist 607 $aMalta$2fast 608 $aPeriodicals.$2fast 608 $aStatistics.$2fast 608 $aPeriodicals.$2lcgft 615 0$aBalance of payments 615 0$aBalance of payments 615 7$aBalance of payments. 615 7$aZahlungsbilanzstatistik. 615 7$aMalta. 615 17$aFINANCIAL STATISTICS. 615 17$aBALANCE OF PAYMENTS. 615 17$aEXTERNAL DEBT. 615 17$aMALTA. 712 02$aMalta.$bNational Statistics Office. 906 $aJOURNAL 912 $a9910893075903321 920 $aexl_impl conversion 996 $aBALANCE of payments$9575598 997 $aUNINA LEADER 03304nam 22005895 450 001 9910254025903321 005 20200705061557.0 010 $a3-319-20040-2 024 7 $a10.1007/978-3-319-20040-8 035 $a(CKB)3710000000711712 035 $a(DE-He213)978-3-319-20040-8 035 $a(MiAaPQ)EBC4533798 035 $a(PPN)194074145 035 $a(EXLCZ)993710000000711712 100 $a20160527d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aComputational Modelling of the Human Islet Amyloid Polypeptide /$fby Katrine Kirkeby Skeby 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (XVI, 118 p. 58 illus., 47 illus. in color.) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 300 $a"Doctoral thesis accepted by the Aarhus University, Aarhus C, Denmark." 311 $a3-319-20039-9 320 $aIncludes bibliographical references at the end of each chapters. 327 $aAmyloid and Amyloid Fibrils -- Computational Theory -- Imaging Agent Binding to Amyloid Protofibrils -- Determining the Aggregation Prone Structure of hiAPP -- Effect of Terminal Capping on Aggregation of Peptide Fragments -- Coarse Grained Study of Amyloid Protofibril Aggregation -- Conclusion and Perspectives. 330 $aThis thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this research provides unparalleled insights, especially with regard to the origin of cytotoxicity and to developing technologies for early detection, revealing in detail the molecular mechanisms behind hIAPP behavior. Several studies within the thesis answer difficult questions which promote future research into the properties of amyloid proteins. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aPharmaceutical chemistry 606 $aCheminformatics 606 $aBioorganic chemistry 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 606 $aComputer Applications in Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C13009 606 $aBioorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19010 615 0$aPharmaceutical chemistry. 615 0$aCheminformatics. 615 0$aBioorganic chemistry. 615 14$aMedicinal Chemistry. 615 24$aComputer Applications in Chemistry. 615 24$aBioorganic Chemistry. 676 $a540 700 $aSkeby$b Katrine Kirkeby$4aut$4http://id.loc.gov/vocabulary/relators/aut$01059821 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254025903321 996 $aComputational Modelling of the Human Islet Amyloid Polypeptide$92508528 997 $aUNINA