LEADER 03525nam 22006615 450 001 9910887888503321 005 20250807132434.0 010 $a3-031-62232-4 024 7 $a10.1007/978-3-031-62232-8 035 $a(MiAaPQ)EBC31681001 035 $a(Au-PeEL)EBL31681001 035 $a(CKB)35895633200041 035 $a(DE-He213)978-3-031-62232-8 035 $a(EXLCZ)9935895633200041 100 $a20240917d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMolecular and Cell Biology of Pancreas Development, Function and Regeneration /$fedited by Maria L. Golson 205 $a1st ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2024. 215 $a1 online resource (201 pages) 225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v239 311 08$a3-031-62231-6 327 $aAlpha Cell Contribution to Glucose Homeostasis -- Delta Cell Contribution to Glucose Homeostasis -- Islet Cell Plasticity Including Beta-Cell Dedifferentiation?Combined with Beta-Cell Heterogeneity -- Epigenetic Regulation of Pancreas Development and Function -- Beta-Cell Differentiation in vitro -- Endocrine Pancreas Regeneration -- Ductal Cell Development -- Relationship Between Beta-Cell Function and Beta-Cell Proliferation -- Maternal and Paternal Environmental Impacts on Beta-Cell Development -- Beyond Sugar: How Fat and Protein Contribute to the Regulation of Insulin Secretion -- Channels Involved in Regulating Insulin Secretion. 330 $aThis book reviews recent advances in pancreatic endocrine and exocrine tissue development, function and regeneration. It provides a comprehensive overview on different aspects of beta-cell biology, including heterogeneity of function and gene expression and function, epigenetics, RNA and protein expression contributions to beta-cell specification and cell-fate maintenance. Furthermore, it covers recent progress in differentiating functional islets in vivo, environmental impacts on beta-cell development and function, and communications between various islet endocrine cells and how they contribute to the regulation of blood glucose homeostasis. The book provides a comprehensive resource for understanding the various compartments of the pancreas and is aimed at pancreas, beta-cell biology, and diabetes researchers. 410 0$aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v239 606 $aCytology 606 $aDigestion 606 $aPhysiology 606 $aGastrointestinal system 606 $aGastrointestinal system 606 $aInternal medicine 606 $aCell Biology 606 $aDigestive System Physiology 606 $aGastrointestinal System 606 $aInternal Medicine 615 0$aCytology. 615 0$aDigestion. 615 0$aPhysiology. 615 0$aGastrointestinal system. 615 0$aGastrointestinal system. 615 0$aInternal medicine. 615 14$aCell Biology. 615 24$aDigestive System Physiology. 615 24$aGastrointestinal System. 615 24$aInternal Medicine. 676 $a571.6 700 $aGolson$b Maria L$01769632 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910887888503321 996 $aMolecular and Cell Biology of Pancreas Development, Function and Regeneration$94241400 997 $aUNINA