LEADER 04091nam 22006375 450 001 9910881094303321 005 20250807135533.0 010 $a981-9989-21-3 024 7 $a10.1007/978-981-99-8921-8 035 $a(MiAaPQ)EBC31608164 035 $a(Au-PeEL)EBL31608164 035 $a(CKB)34119679500041 035 $a(DE-He213)978-981-99-8921-8 035 $a(EXLCZ)9934119679500041 100 $a20240819d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTranslational Research in Pain and Itch /$fedited by Chao Ma, Yuguang Huang 205 $a2nd ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (0 pages) 311 08$a981-9989-20-5 320 $aIncludes bibliographical references. 327 $aChapter 1 Assessment of Itch and Pain in Animal Models and Human Subjects -- Chapter 2 Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse -- Chapter 3 Modulation of C-nociceptive Activities by Inputs from Myelinated Fibers -- Chapter 4 Pathophysiologic basis of the treatment of spontaneous pain -- Chapter 5 Neuropathic Pain: Sensory Nerve Injury or Motor Nerve Injury? -- Chapter 6 T cell and subsets in neuropathic pain -- Chapter 7 Astrocyte and microglia in chronic postsurgical pain -- Chapter 8 Dorsal spinal modulation of neuraxial opioids induced pruritus -- Chapter 9 Peripheral Nociceptors as Immune Sensors in the Development of Pain and Itch -- Chapter 10 Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy -- Chapter 11 Pain Modulation and the Transition from Acute to Chronic Pain -- Chapter 12 Integrated, Team-Based Chronic Pain Management: Bridges from Theory and Research to High Quality Patient Care -- Chapter 13 Research progress of long-acting analgesics for the treatment of chronic pain -- Chapter 14 Update in the Treatment of Neuropathic Pain -- Chapter 15 Mechanisms of peripheral sensitization in neuropathic pain. 330 $aThis book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these conditions occur. Based on these findings, a series of novel treatment strategies are currently under development, and hopefully in a few years, medical practitioners will become more confident and optimistic when facing patients with these annoying and sometimes severe disorders. The contributing authors are world-renowned research scientists, who have made significant discoveries. The book is of interest to neuroscientists, neurologists and pharmacologists in both clinical and basic medical research field. In this second edition of the book, five existing chapters have been updated. Fivenew chapters have been added to reflect the lasted developments in the related field of research. 606 $aNeurosciences 606 $aHuman physiology 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aPain medicine 606 $aNeuroscience 606 $aHuman Physiology 606 $aBiomedical Research 606 $aPain Medicine 615 0$aNeurosciences. 615 0$aHuman physiology. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aPain medicine. 615 14$aNeuroscience. 615 24$aHuman Physiology. 615 24$aBiomedical Research. 615 24$aPain Medicine. 676 $a612.88 702 $aMa$b Chao$f1973- 702 $aHuang$b Yuguang 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910881094303321 996 $aTranslational Research in Pain and Itch$94207214 997 $aUNINA