LEADER 05268nam 2200625Ia 450 001 9910877778903321 005 20200520144314.0 010 $a1-280-51985-1 010 $a9786610519859 010 $a3-527-60478-2 010 $a3-527-60456-1 035 $a(CKB)1000000000377111 035 $a(EBL)481488 035 $a(OCoLC)170935232 035 $a(SSID)ssj0000259656 035 $a(PQKBManifestationID)11209453 035 $a(PQKBTitleCode)TC0000259656 035 $a(PQKBWorkID)10186301 035 $a(PQKB)10230147 035 $a(MiAaPQ)EBC481488 035 $a(EXLCZ)991000000000377111 100 $a20040818d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aTissue engineering $eessentials for daily laboratory work /$fW.W. Minuth, R. Strehl, K. Schumacher 210 $aWeinheim ;$a[New York] $cWiley-VCH$dc2005 215 $a1 online resource (328 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31186-6 320 $aIncludes bibliographical references (p. 303-305) and index. 327 $aTissue Engineering; Preface; Contents; 1 Developmental processes; 2 Cells and Tissue; 2.1 The Cell; 2.1.1 The Cell as a Functional Unit; 2.1.2 Plasma Membrane; 2.1.3 Nucleus; 2.1.4 Mitochondria; 2.1.5 Endoplasmic Reticulum (ER); 2.1.6 Golgi Apparatus; 2.1.7 Endosomes, Lysosomes and Peroxisomes; 2.1.8 Cytoskeleton; 2.1.9 ECM; 2.1.10 Cell Cycle; 2.2 Tissue Types; 2.2.1 Epithelia; 2.2.1.1 Building Plans of Epithelia; 2.2.1.2 Glands; 2.2.1.3 Epithelia in Sensory Perception; 2.2.2 Connective Tissue; 2.2.2.1 Variety; 2.2.2.2 Fat Tissue as Storage; 2.2.2.3 Bone and Cartilage as Support Tissue 327 $a2.2.3 Muscle Tissue2.2.3.1 Cell Movement; 2.2.3.2 Rhythmic Contraction; 2.2.3.3 Unconscious Contraction; 2.2.4 Nervous System Tissue; 2.2.4.1 Information Mediation; 2.2.4.2 Networks and Connections; 2.3 Relevance of the ECM; 2.3.1 Components of the ECM; 2.3.1.1 Functions of the ECM; 2.3.1.2 Synthesis of the Collagens; 2.3.1.3 Fibronectin; 2.3.1.4 Laminin; 2.3.1.5 Reticular and Elastic Fibers; 2.3.1.6 Collagens of the Basement Membrane; 2.3.1.7 FACIT Collagens; 2.3.1.8 Proteoglycans; 2.3.2 Interactions between the Cell and the ECM; 2.3.2.1 Adhesion and the ECM 327 $a2.3.2.2 Proliferation and the ECM2.3.2.3 Differentiation and the ECM; 2.3.2.4 Apoptosis and the ECM; 2.3.3 Signal Transduction; 2.3.3.1 Modulation of the Cell-Matrix Interaction; 2.3.3.2 The ECM and Cell Binding; 2.3.3.3 Signals to the Inner Cell; 2.3.3.4 The ECM and Long-term Contact; 2.3.4 Matricellular Proteins; 2.3.4.1 Thrombospondin; 2.3.4.2 Tenascin C; 2.3.4.3 Osteopontin; 2.3.4.4 SPARC; 2.4 Emergence of Tissue; 2.4.1 Germ Layers and Ground Tissue; 2.4.1.1 Derivatives of the Ectoderm; 2.4.1.2 Derivatives of the Mesoderm; 2.4.1.3 Derivatives of the Entoderm 327 $a2.4.2 Individual Cells, Social Interactions and Functional Tissue Development2.4.2.1 Differentiation from Individual Cells; 2.4.2.2 Functional Exceptions; 2.4.2.3 Individual Cells and Social Interactions; 2.4.2.4 Formation of tissue; 2.4.2.5 Individual Cell Cycles; 2.4.2.6 Coordinated Growth; 2.4.2.7 Competence; 2.4.2.8 Morphogenic Factors; 2.4.2.9 Apoptosis; 2.4.2.10 Necrosis versus Apoptosis; 2.4.2.11 Terminal Differentiation; 2.4.2.12 Adaptation; 2.4.2.13 Transdifferentiation; 2.4.2.14 Multifactorial Differentiation; 2.5 Regeneration; 2.5.1 Events Immediately after an Injury 327 $a2.5.2 Wound Closure2.5.3 Programmed Cell Death (Apoptosis); 2.5.4 Cooperative Renewal; 3 Classical Culture Methods; 3.1 History; 3.2 First Cultures; 3.2.1 Culture Containers; 3.2.1.1 Individual Culture Containers; 3.2.1.2 Dimensions of the Container; 3.2.1.3 Coating the Culture Dish; 3.2.1.4 Filter Inserts; 3.2.2 Culture Media; 3.2.2.1 Ingredients; 3.2.2.2 Adjustment of Serum Supplements; 3.2.2.3 Serum Collection; 3.2.2.4 Serum-free Culture Media; 3.2.2.5 pH of the Medium; 3.2.2.6 Antibiotics; 3.2.2.7 Other Additives; 3.2.3 Growth Factors; 3.2.3.1 Overview of Different Growth Factors 327 $a3.2.3.2 Effect of Growth Factors 330 $aComprehensive in its scope and illustrated in detail, this practical book provides a fundamental insight into the complex world of tissue development and artificial cell culture using tissue engineering.The introductory chapters cover basic cell biology and cellular development as well as cell culture, with a main emphasis on ways of differentiating tissue and the critical evaluation of the properties of maturing tissue constructs. The authors also focus on the use of stem cells from the most varied sources in tissue engineering. The whole is rounded off by an exceptionally wide-rangin 606 $aTissue engineering 606 $aTissue culture$vLaboratory manuals 615 0$aTissue engineering. 615 0$aTissue culture 676 $a571.538 700 $aMinuth$b W. W$g(Will W.)$01752175 701 $aStrehl$b R$g(Raimund)$01752176 701 $aSchumacher$b K$g(Karl)$01752177 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877778903321 996 $aTissue engineering$94192562 997 $aUNINA