LEADER 03784nam 2200649Ia 450 001 9910877678703321 005 20200520144314.0 010 $a1-282-28012-0 010 $a9786612280122 010 $a0-470-43798-7 010 $a0-470-43797-9 035 $a(CKB)1000000000789578 035 $a(EBL)455922 035 $a(OCoLC)466446801 035 $a(SSID)ssj0000354813 035 $a(PQKBManifestationID)11258216 035 $a(PQKBTitleCode)TC0000354813 035 $a(PQKBWorkID)10314583 035 $a(PQKB)10641838 035 $a(MiAaPQ)EBC455922 035 $a(EXLCZ)991000000000789578 100 $a20080624d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSystems biology and synthetic biology /$fedited by Pengcheng Fu, Sven Panke 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2009 215 $a1 online resource (674 p.) 300 $aDescription based upon print version of record. 311 $a0-471-76778-6 320 $aIncludes bibliographical references and index. 327 $aSYSTEMS BIOLOGY AND SYNTHETIC BIOLOGY; CONTENTS; Foreword; Contributors; 1 Introduction; 2 Basics of Molecular Biology, Genetic Engineering, and Metabolic Engineering; 3 High-Throughput Technologies and Functional Genomics; 4 Genomic Signal Processing of DNA Microarray Data for the Enhanced Prediction of Axillary Lymph Node Status of Breast Cancer Tumors; 5 Recombinant Genomes: Novel Resources for Systems Biology and Synthetic Biology; 6 In silico Genome-Scale Metabolic Models: The Constraint-Based Approach and its Applications 327 $a7 Mathematical Modeling of Genetic Regulatory Networks: Stress Responses in Escherichia coli8 Synthetic Life: Ethobricks for a New Biology; 9 Yeast as a Prototype for Systems Biology; 10 Construction and Applications of Genome-Scale in silico Metabolic Models for Strain Improvement; 11 Synthetic Biology: Putting Engineering into Bioengineering; 12 Rationales of Gene Design and de novo Gene Construction; 13 Self-Replication in Chemistry and Biology; 14 The Synthetic Approach for Regulatory and Metabolic Circuits; 15 Synthetic Gene Networks 327 $a16 The Theory of Biological Robustness and its Implication to Cancer17 Nucleic Acid Engineering; 18 Potential Applications of Synthetic Biology in Marine Microbial Functional Ecology and Biotechnology; 19 On Fundamental Implications of Systems and Synthetic Biology; 20 Outstanding Issues in Systems and Synthetic Biology; Index 330 $aThe genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology 606 $aBiotechnology 606 $aGenetic engineering 606 $aBiological systems 615 0$aBiotechnology. 615 0$aGenetic engineering. 615 0$aBiological systems. 676 $a660.6 686 $aBIO 180f$2stub 686 $aCIT 972f$2stub 686 $aWD 9200$2rvk 686 $aWH 2000$2rvk 701 $aFu$b Pengcheng$01754326 701 $aPanke$b Sven$01754327 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877678703321 996 $aSystems biology and synthetic biology$94190613 997 $aUNINA