LEADER 03226nam 2200601Ia 450 001 9910877633003321 005 20200520144314.0 010 $a1-282-03426-X 010 $a9786612034268 010 $a0-470-74189-9 010 $a0-470-74190-2 035 $a(CKB)1000000000687275 035 $a(EBL)416483 035 $a(OCoLC)476248377 035 $a(SSID)ssj0000226366 035 $a(PQKBManifestationID)11210196 035 $a(PQKBTitleCode)TC0000226366 035 $a(PQKBWorkID)10259005 035 $a(PQKB)10144141 035 $a(MiAaPQ)EBC416483 035 $a(PPN)152528962 035 $a(EXLCZ)991000000000687275 100 $a20080912d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPrediction of protein structures, functions, and interactions /$fedited by Janusz M. Bujnicki 210 $aChichester, U.K. $cWiley$d2009 215 $a1 online resource (306 p.) 300 $aDescription based upon print version of record. 311 $a0-470-51767-0 320 $aIncludes bibliographical references and index. 327 $aPrediction of Protein Structures, Functions, and Interactions; Contents; List of Contributors; Preface; 1 The Basics of Protein Sequence Analysis; 2 First Steps of Protein Structure Prediction; 3 Automated Prediction of Protein Function from Sequence; 4 Template Based Prediction of Three-dimensional Protein Structures: Fold Recognition and Comparative Modeling; 5 Template-free Predictions of Three-dimensional Protein Structures: From First Principles to Knowledge-based Potentials; 6 Quality Assessment of Protein Models 327 $a7 Prediction of Molecular Interactions from 3D-structures: From Small Ligands to Large Protein Complexes8 Structure-based Prediction of Enzymes and Their Active Sites; 9 The Prediction of Macromolecular Complexes by Docking; 10 Protein Function Prediction via Analysis of Interactomes; 11 Integrating Prediction of Structure, Function, and Interactions; Index; Color Plate 330 $aThe growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of comp 606 $aProteins$xStructures 606 $aAmino acid sequence 606 $aProtein-protein interactions 615 0$aProteins$xStructures. 615 0$aAmino acid sequence. 615 0$aProtein-protein interactions. 676 $a572.633 676 $a572/.633 701 $aBujnicki$b Janusz M$0731294 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877633003321 996 $aPrediction of protein structures, functions, and interactions$94186349 997 $aUNINA