LEADER 05356nam 2200625Ia 450 001 9910877295803321 005 20200520144314.0 010 $a1-281-32163-X 010 $a9786611321635 010 $a0-470-76009-5 010 $a0-470-75982-8 035 $a(CKB)1000000000405962 035 $a(EBL)351254 035 $a(OCoLC)815644680 035 $a(SSID)ssj0000194696 035 $a(PQKBManifestationID)11157014 035 $a(PQKBTitleCode)TC0000194696 035 $a(PQKBWorkID)10232918 035 $a(PQKB)10853870 035 $a(MiAaPQ)EBC351254 035 $a(EXLCZ)991000000000405962 100 $a19990607d2000 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aLower genital tract precancer $ecolposcopy, pathology and treatment /$fAlbert Singer, John M. Monaghan ; assistant author, Swee Chong Quek ; contributing author Alastair R.S. Deery 205 $a2nd ed. 210 $aOxford ;$aMalden, MA $cBlackwell Science$d2000 215 $a1 online resource (341 p.) 300 $aDescription based upon print version of record. 311 $a0-632-04769-0 320 $aIncludes bibliographical references and index. 327 $aLower Genital Tract Precancer; Contents; Preface to the Second Edition; Preface to the First Edition; Acknowledgements; 1 The Histopathology of Lower Genital Tract Neoplasia; 1.1 Introduction; 1.2 Terminology; The concept of cervical cancer precursors; Biology and natural history; Rationalization of histologic terminology; 1.3 Histopathological features of CIN or SIL; Low-grade disease (mild dysplasia, CIN 1, HPV-CIN 1, LSIL); High-grade disease (moderate or severe dysplasia, CIS, CIN 2 or 3, HSIL); 1.4 Cervical glandular intraepithelial neoplasia and adenocarcinoma-in-situ 327 $aCervical glandular intraepithelial neoplasiaHistologic criteria for CGIN; 1.5 Early invasive carcinoma (microinvasive carcinoma of the cervix); 1.6 Vaginal intraepithelial neoplasia; Adenosis; Histopathology of vaginal intraepithelial neoplasia; 1.7 Vulval precancer; Vulval intraepithelial neoplasia; Paget's disease; 1.8 Related topics; 1.9 References and bibliography; 2 Human Papillomaviruses in Pathogenesis of Lower Genital Tract Neoplasia; 2.1 Introduction; 2.2 Characteristics of human papillomavimses; 2.3 Manifestations of genital HPV infections 327 $aClinical infections (predominately condylomata)Subclinical HPV infections; Latent HPV infections; 2.4 Prevalence of genital HPV infections; Incidence rates of HPV infections; 2.5 Transmission of genital HPV infections; Sexual transmission; Vertical transmission; 2.6 Risk factors for genital HPV infections; 2.7 HPV and cancer precursors; 2.8 HPV infections and the risk for cervical cancer; Case reports and case series; Cohort studies; 2.9 Natural history; Natural history of cervical HPV infections; CIN and HPV have an identical natural history; 2.10 Molecular pathways of HPV oncogenesis 327 $aThe normal cell cycleThe effect of HPV/host cell interaction-a prerequisite for neoplasia; 2.11 The role of oncogenic HPV detection in the prevention of lower genital tract precancer; As an adjunct to cytology in primary screening; As an adjunct to colposcopy in the management of women presenting with mild or borderline dyskaryosis (ASCUS/AGUS); 2.12 HPV type and type variant as determinants of the natural history; 2.13 References and bibliography; 3 Examination for Cervical Precancer-Use of colposcopy; 3.1 Introduction; 3.2 Tissue basis for colposcopy; The role of the epithelium 327 $aThe role of the stromaThe role of the surface configuration; 3.3 The colposcopic examination; The colposcope; The examination; Decontamination of colposcopy clinic equipment; 3.4 New developments in colposcopy; Video colposcopy, image management and electronic databases; 3.5 References and bibliography; 4 Colposcopy of the Normal Cervix -A prerequisite to establish the diagnosis of cervical cancer; 4.1 Introduction; 4.2 Cervical epithelium: natural history; 4.3 Cervical epithelium: topography; 4.4 Cervical epithelium: colposcopic appearances; Original columnar epithelium 327 $aOriginal squamous epithelium 330 $aThe new Second Edition of Lower Genital Tract Precancer has been extensively revised and expanded to provide a definitive and contemporary reference on this subject. Providing a comprehensive examination of the applications and benefits of modern diagnostic and therapeutic practices in managing lesions of the female lower genital tract, the book is presented in a clear, easy-to-read style and is extensively illustrated. The text covers investigative procedures and techniques, reviews the normal and abnormal cervix and fully appraises the diagnosis and management of both benign and malig 606 $aGenerative organs, Female$xPrecancerous conditions 606 $aCancer 615 0$aGenerative organs, Female$xPrecancerous conditions. 615 0$aCancer. 676 $a616.99/466 700 $aSinger$b Albert$0903337 701 $aMonaghan$b John M$0925979 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877295803321 996 $aLower genital tract precancer$92078989 997 $aUNINA