LEADER 05412nam 2200625Ia 450 001 9910877232003321 005 20200520144314.0 010 $a1-282-54953-7 010 $a9786612549533 010 $a1-4443-1841-1 010 $a1-4443-1842-X 035 $a(CKB)2670000000014735 035 $a(EBL)514402 035 $a(OCoLC)609862760 035 $a(SSID)ssj0000361611 035 $a(PQKBManifestationID)11305321 035 $a(PQKBTitleCode)TC0000361611 035 $a(PQKBWorkID)10351872 035 $a(PQKB)10399973 035 $a(MiAaPQ)EBC514402 035 $a(EXLCZ)992670000000014735 100 $a20090721d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aInflammatory bowel disease $etranslating basic science into clinical practice /$fedited by Stephan R. Targan, Fergus Shanahan, Loren C. Karp 210 $aChichester, West Sussex ;$aHoboken, NJ $cBlackwell Pub.$d2010 215 $a1 online resource (760 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-5725-9 320 $aIncludes bibliographical references and index. 327 $aInflammatory Bowel Disease; Contents; List of Contributors; Preface; 1 Introduction: the Science and the Art of Inflammatory Bowel Disease; 2 Heterogeneity of Inflammatory Bowel Diseases; 3 Epidemiology of Inflammatory Bowel Disease: the Shifting Landscape; 4 Genetics of Inflammatory Bowel Disease: How Modern Genomics Informs Basic, Clinical and Translational Science; 5 In Vivo Models of Inflammatory Bowel Disease; 6 Factors Affecting Mucosal Homeostasis: a Fine Balance; 7 Innate Immunity and its Implications on Pathogenesis of Inflammatory Bowel Disease 327 $a8 Adaptive Immunity: Effector and Inhibitory Cytokine Pathways in Gut Inflammation9 Host Response to Bacterial Homeostasis; 10 Cytokines and Chemokines in Mucosal Homeostasis; 11 The Role of the Vasculature in Chronic Intestinal Inflammation; 12 Biological Basis of Healing and Repair in Remission and Relapse; 13 The Bidirectional Relationship of Gut Physiological Systems and the Mucosal Immune System; 14 Extraintestinal Consequences of Mucosal Inflammation; 15 Ulcerative Colitis and Ulcerative Proctitis: Clinical Course and Complications; 16 Crohn's Disease: Clinical Course and Complications 327 $a17 Practical Inflammatory Bowel Disease Pathology in Patient Management18 The Role of Endoscopy in Diagnosis and Treatment of Inflammatory Bowel Disease; 19 Imaging in Inflammatory Bowel Disease: Computed Tomography and Magnetic Resonance Enterography, Ultrasound and Enteroscopy; 20 New Diagnostic Approaches: Integrating Serologics, Endoscopy and Radiology and Genomics; 21 Considerations in the Differential Diagnosis of Colitis; 22 Disease Management in Chronic Medical Conditions and its Relevance to Inflammatory Bowel Disease; 23 Outcomes, Disease Activity Indices and Study Design 327 $a24 Non-targeted Therapeutics for Inflammatory Bowel Diseases25 Targeted Treatments for Inflammatory Bowel Diseases; 26 Therapeutic Manipulation of the Microbiota in Inflammatory Bowel Disease: Antibiotics and Probiotics; 27 The Role of Nutrition in the Evaluation and Treatment of Inflammatory Bowel Disease; 28 Therapeutic Approaches to the Treatment of Ulcerative Colitis; 29 Surgical Considerations for Ulcerative Colitis; 30 Clinical Characteristics and Management of Pouchitis and Ileal Pouch Disorders; 31 Therapeutic Approaches to the Treatment of Crohn's Disease 327 $a32 Surgical Considerations for the Patient with Crohn's Disease/Perianal Crohn's Disease33 Diagnostic and Therapeutic Approaches to Postoperative Recurrence in Crohn's Disease; 34 Molecular Alterations Associated with Colitis-associated Colon Carcinogenesis; 35 Cancer Surveillance in Inflammatory Bowel Disease; 36 Liver Diseases in Patients with Inflammatory Bowel Diseases; 37 Conditions of the Eyes and Joints Associated with Inflammatory Bowel Disease; 38 Dermatologic Conditions Associated with Inflammatory Bowel Diseases; 39 Fertility and Pregnancy in Inflammatory Bowel Diseases 327 $a40 Inflammatory Bowel Disease in the Pediatric Population 330 $aThis is the state-of-the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn 606 $aInflammatory bowel diseases 606 $aInflammatory bowel diseases$xPathophysiology 615 0$aInflammatory bowel diseases. 615 0$aInflammatory bowel diseases$xPathophysiology. 676 $a616.3/44 701 $aTargan$b Stephan R$0946843 701 $aShanahan$b Fergus$0909421 701 $aKarp$b Loren C$0946844 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877232003321 996 $aInflammatory bowel disease$92139153 997 $aUNINA