LEADER 04175nam 2200649Ia 450 001 9910877181203321 005 20200520144314.0 010 $a1-282-48220-3 010 $a9786612482205 010 $a0-470-68583-2 010 $a0-470-68584-0 035 $a(CKB)2550000000007388 035 $a(EBL)485679 035 $a(OCoLC)604996137 035 $a(SSID)ssj0000354225 035 $a(PQKBManifestationID)11245282 035 $a(PQKBTitleCode)TC0000354225 035 $a(PQKBWorkID)10302853 035 $a(PQKB)11115062 035 $a(MiAaPQ)EBC485679 035 $a(PPN)243140983 035 $a(EXLCZ)992550000000007388 100 $a20091028d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFunctionalised N-heterocyclic carbene complexes /$fOlaf Kuhl 210 $aChichester, West Sussex $cWiley$d2010 215 $a1 online resource (365 p.) 300 $aDescription based upon print version of record. 311 $a0-470-71215-5 320 $aIncludes bibliographical references and index. 327 $aCover; Contents; Abbreviations; Introduction; Chapter 1 The Nature of N-Heterocyclic Carbenes; 1.1 Synthesis; 1.1.1 Synthesis of the Imidazolium Salts; 1.1.2 Closing the Ring; 1.1.3 Synthesis of the Free Carbenes; 1.1.4 Synthesis of Transition Metal Complexes of NHC; 1.2 Properties of NHC; 1.2.1 The Internal Electronic Structure; 1.2.2 Basicity of NHC; 1.2.3 Steric Properties; 1.2.4 The Carbene-Metal Bond; 1.2.5 Decomposition Pathways; References; Chapter 2 Why Functionalisation?; 2.1 Phosphane Mimic; 2.2 Hemilability; 2.3 Chirality; 2.3.1 Planar Chirality; 2.3.2 Axial Chirality 327 $a2.4 Ligand Geometry2.5 Catalysis; 2.5.1 Allylic Alkylation; 2.5.2 Coupling Reactions; 2.5.3 Olefin Metathesis; 2.5.4 Polymerisations; 2.5.5 Organocatalysis; References; Chapter 3 N-Heterocyclic Carbenes with Neutral Tethers; 3.1 Amine Functionalities; 3.1.1 Heteroaromatic Functional Groups; 3.1.2 Oxazolines; 3.1.3 Imino Functional Groups; 3.1.4 Amino Functionalised NHC; 3.2 Oxygen-Containing Groups; 3.3 Phosphane Functionalities; 3.4 Bis-Carbene Ligands; 3.5 Tris-N-Heterocyclic Carbene Ligands; 3.6 Pincer Carbenes; References; Chapter 4 N-Heterocyclic Carbenes with Anionic Functional Groups 327 $a4.1 Oxygen-Containing Groups4.2 Nitrogen-Containing Groups; 4.3 NHC Ligands Incorporating Cp Moieties; 4.4 Transition Metal NHC Complexes Involved in the Activation of C-H Bonds; 4.5 Immobilisation of the Catalyst; 4.6 Sulfur-Containing Functional Groups; References; Chapter 5 Chiral N-Heterocyclic Carbenes; References; Chapter 6 Natural Products; 6.1 Thiazole; 6.1.1 Isolation and Stability of Thiazolylidene; 6.1.2 Benzothiazoles; 6.1.3 Metal Complexes; 6.2 Amino Acids; 6.3 Purines and Xanthines; 6.4 Carbohydrates; 6.5 Miscellaneous; References; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N 327 $aOP; Q; R; S; T; U; V; W; X; Z 330 $aN-heterocyclic carbenes (NHCs) have found increasing use as reagents for a range of organic transformations and in asymmetric organocatalysis. The performance of these molecules can be improved and tuned by functionalisation. Functionalised carbenes can anchor free carbenes to the metal site, introduce hemilability, provide a means to immobilise transition metal carbene catalysts, introduce chirality, provide a chelate ligand or bridge two metal centres. NHC can be attached to carbohydrates and campher, derived from amino acids and purines, they can be used as organocatalysts mimicking vitamin 606 $aLigands 606 $aHeterocyclic compounds 606 $aTransition metal complexes 615 0$aLigands. 615 0$aHeterocyclic compounds. 615 0$aTransition metal complexes. 676 $a541/.2242 686 $aCHE 330f$2stub 686 $aCHE 612f$2stub 686 $aCHE 670f$2stub 700 $aKuhl$b Olaf$01763865 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910877181203321 996 $aFunctionalised N-heterocyclic carbene complexes$94204514 997 $aUNINA