LEADER 02919nam 22005774a 450 001 9910876973203321 005 20200520144314.0 010 $a1-281-32178-8 010 $a9786611321789 010 $a0-470-72430-7 010 $a0-470-72429-3 035 $a(CKB)1000000000377090 035 $a(EBL)351029 035 $a(SSID)ssj0000127651 035 $a(PQKBManifestationID)11140059 035 $a(PQKBTitleCode)TC0000127651 035 $a(PQKBWorkID)10061929 035 $a(PQKB)10478583 035 $a(MiAaPQ)EBC351029 035 $a(PPN)152256075 035 $a(OCoLC)184983256 035 $a(EXLCZ)991000000000377090 100 $a20070928d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aComputational methods for mass spectrometry proteomics /$fIngvar Eidhammer ... [et al.] 210 $aChichester, England ;$aHoboken, NJ $cJohn Wiley & Sons$dc2007 215 $a1 online resource (298 p.) 300 $aDescription based upon print version of record. 311 $a0-470-51297-0 320 $aIncludes bibliographical references (p. [265]-275) and index. 327 $aProtein, proteome, and proteomics -- Protein separation : 2D gel electrophoresis -- Protein digestion -- Peptide separation : HPLC -- Fundamentals of mass spectrometry -- Mass spectrometry : MALDI-TOF -- Protein identification and characterization by MS -- Tandem MS or MS/MS analysis -- Fragmentation models -- Identification and characterization by MS/MS -- Spectral comparisons -- Sequential comparison : de novo sequencing -- Database searching for de novo sequences -- Large-scale proteomics -- Quantitative MS-based proteomics -- Peptides to proteins -- Top-down proteomics -- Standards. 330 $aProteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. Computational Methods for Mass Spectrometry Proteomics describ 606 $aProteomics$xData processing 606 $aMass spectrometry$xData processing 606 $aBioinformatics 615 0$aProteomics$xData processing. 615 0$aMass spectrometry$xData processing. 615 0$aBioinformatics. 676 $a572/.60285 701 $aEidhammer$b Ingvar$01751303 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910876973203321 996 $aComputational methods for mass spectrometry proteomics$94203105 997 $aUNINA