LEADER 03917nam 2200673 a 450 001 9910876914103321 005 20200520144314.0 010 $a1-282-34766-7 010 $a9786612347665 010 $a0-470-51394-2 010 $a0-470-51395-0 035 $a(CKB)1000000000377243 035 $a(EBL)470468 035 $a(OCoLC)609849376 035 $a(SSID)ssj0000304163 035 $a(PQKBManifestationID)11244021 035 $a(PQKBTitleCode)TC0000304163 035 $a(PQKBWorkID)10278792 035 $a(PQKB)10734507 035 $a(MiAaPQ)EBC470468 035 $a(EXLCZ)991000000000377243 100 $a19900403d1990 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNeurobiology of incontinence 210 $aChichester, West Sussex, England ;$aNew York $cWiley$d1990 215 $a1 online resource (348 p.) 225 1 $aCiba Foundation symposium ;$v151 300 $aBased on a symposium held at the Ciba Foundation, London, Oct. 11-13, 1989. 300 $aEdited by Greg Bock (organizer) and Julie Whelan. 300 $a"A Wiley-Interscience publication." 311 $a0-471-92687-6 320 $aIncludes bibliographical references and indexes. 327 $aNEUROBIOLOGY OF INCONTINENCE; Contents; Introduction; Innervation of bladder and bowel; Central neural control of the lower urinary tract; Functional anatomy of the female lower urinary tract and pelvic floor; The dual function of capsaicin-sensitive sensory nerves in the bladder and urethra; The spinal pharmacology of urinary function: studies on urinary continence in the unanaesthetized rat; General discussion I : Functional and anatomical correlates; Correlations between urinary and anorectal systems; Functional assessment of the anorectum in faecal incontinence 327 $aFunctional assessment of the bladderThe neurogenic hypothesis of stress incontinence; General discussion II : Rectal function and parallels with urinary continence; Stress urinary incontinence; Detrusor-external sphincter dyssynergia; General discussion III : Stress urinary incontinence: mechanisms and problems; The physiological evaluation of operative repair for incontinence and prolapse; Surgical approaches to anal incontinence; Treatment of urinary and faecal incontinence by surgically implanted devices 327 $aGeneral discussion IV : Effects of denervation: smooth muscle hypertrophy and nerve regenerationPharmacological therapy for urinary incontinence; Final general discussion; Index of contributors; Subject index 330 $aIncontinence is a very common and often devastating problem, but one that goes largely unacknowledged. In order to elucidate the underlying mechanisms of this major clinical condition, this symposium brought together neuroscientists working on the basic biology of the bladder and bowel and clinicians dealing with the various manifestations of urinary and fecal incontinence. The resulting coverage is broad and includes papers on the innervation and functional anatomy of the urinary tract and anorectal region, and the central neural control of these areas. Other contributions discuss the functio 410 0$aCiba Foundation symposium ;$v151. 606 $aUrinary incontinence$vCongresses 606 $aFecal incontinence$vCongresses 606 $aUrinary organs$xInnervation$vCongresses 606 $aIntestines$xInnervation$vCongresses 615 0$aUrinary incontinence 615 0$aFecal incontinence 615 0$aUrinary organs$xInnervation 615 0$aIntestines$xInnervation 676 $a616.8/49 701 $aBock$b Gregory$0322650 701 $aWhelan$b Julie$0322651 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910876914103321 996 $aNeurobiology of incontinence$94204212 997 $aUNINA