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010   $a9786610272631
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100   $a20000612d2000      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aNeural transplantation in neurodegenerative disease $ecurrent status and new directions /$f[editors Derek J. Chadwick and Jamie A. Goode]
210   $aChichester ;$aNew York $cWiley$d2000
215   $a1 online resource (335 p.)
225 1 $aNovartis Foundation symposium ;$v231
300   $aDescription based upon print version of record.
311   $a0-471-49246-9 
320   $aIncludes bibliographical references and indexes.
327   $aNEURAL TRANSPLANTATION IN NEURODEGENERATIVE DISEASE: CURRENT STATUS AND NEW DIRECTIONS; Contents; Participants; Introduction; Cell replacement strategies for neurodegenerative disorders; Discussion; Functional analysis of fronto-striatal reconstruction by striatal grafts; Discussion; Functional reconstruction of the hippocampus: fetal versus conditionally immortal neuroepithelial stem cell grafts; Discussion; Gene transfer for neuroprotection in animal models of Parkinson's disease and amyotrophic lateral sclerosis; Discussion
327   $aRepair of corticospinal axons by transplantation of olfactory ensheathing cellsDiscussion; Neural transplantation in Parkinson's disease; Discussion; Transplantation of human fetal striatal tissue in Huntington's disease: rationale for clinical studies; Discussion; General discussion I Prospects for fetal transplants; Neurotransplantation in neurodegenerative disease: a survey of relevant issues in developmental neurobiology; Discussion; Molecular and cellular mechanisms in immune rejection of intracerebral neural transplants; Discussion; Porcine neural xenografts: what are the issues?
327   $aDiscussionGene transfer techniques for the delivery of GDNF in Parkinson's disease; Discussion; Neurogenesis in the adult hippocampus; Discussion; Neural stem cells are uniquely suited for cell replacement and gene therapy in the CNS; Discussion; Functional repair with neural stem cells; Discussion; Remyelinating the demyelinated CNS; Discussion; General discussion II The ES cell approach; Final discussion The future for fetal grafts; Stem cell strategies; Index of contributors; Subject index
330   $aThe field of neural transplantation is at a crucial stage, with  important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed. This timely book brings together leading neuroscientists, clinicians, and cell and developmental biologists to discuss the use of neural transplants in neurodegenerative disorders, such as Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord injury. There is also extensive coverage of the potential a
410  0$aNovartis Foundation symposium ;$v231.
606   $aNerve tissue$xTransplantation$vCongresses
606   $aCentral nervous system$xTransplantation$vCongresses
606   $aNervous system$xDegeneration$vCongresses
615  0$aNerve tissue$xTransplantation
615  0$aCentral nervous system$xTransplantation
615  0$aNervous system$xDegeneration
676   $a617.4/80592
676   $a617.4810952
701   $aChadwick$b Derek$091632
701   $aGoode$b Jamie$0283336
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910876906503321
996   $aNeural transplantation in neurodegenerative disease$94195598
997   $aUNINA