LEADER 05077nam 2200601 a 450 001 9910876890403321 005 20200520144314.0 010 $a1-282-68967-3 010 $a9786612689673 010 $a1-4443-0240-X 010 $a1-4443-0241-8 035 $a(CKB)1000000000716003 035 $a(EBL)416495 035 $a(OCoLC)476248471 035 $a(SSID)ssj0000233737 035 $a(PQKBManifestationID)11201138 035 $a(PQKBTitleCode)TC0000233737 035 $a(PQKBWorkID)10235803 035 $a(PQKB)10678555 035 $a(MiAaPQ)EBC416495 035 $a(PPN)151780013 035 $a(EXLCZ)991000000000716003 100 $a20080211g20089999 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aRecent advances in polyphenol research /$fedited by Fouad Daayf, Vincenzo Lattanzio 210 $aOxford ;$aAmes, Iowa $cWiley-Blackwell$d[2008]- 215 $a1 online resource (422 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-5837-9 320 $aIncludes bibliographical references and index. 327 $aContributors; Preface; Chapter 1 Plant Phenolics - Secondary Metabolites with Diverse Functions; 1.1 Secondary metabolism in the interactions between plants and their environment; 1.2 Function and use of plant phenolics; 1.2.1 UV sunscreens; 1.2.2 Phenolics as signal compounds; 1.2.3 Phenolics as pigments; 1.2.4 Phenolics and plant growth; 1.2.5 Phenolics and plant defense; 1.2.5.1 Fungal pathogens; 1.2.5.2 Phenolics and plant-insect interactions; 1.2.6 Plant phenolics and health; 1.3 Note; 1.4 References 327 $aChapter 2 Lignification: are Lignins Biosynthesized via simple Combinatorial Chemistry or via Proteinaceous Control and Template Replication?2.1 Introduction; 2.2 The current theory; 2.3 Is there a need for a new theory?; 2.3.1 The challenge hypothesis (proteinaceous control and template replication); 2.3.2 Has the challenge hypothesis become a theory?; 2.4 Are criticisms of the current theory valid?; 2.4.1 Lignification as a biochemical anomaly; 2.4.2 The -ether frequency anomaly; 2.4.3 'Obligatory' linkages?; 2.5 Is there anything wrong with the dirigent hypothesis? 327 $a2.5.1 Monomer substitution2.5.1.1 Has monomer substitution been disproven?; 2.5.1.2 Malleability of lignification: what makes a good monolignol substitute?; 2.5.2 'Well-defined primary structure'; 2.5.2.1 Sequencing of lignin oligomers; 2.5.2.2 Monomer-independent sequences; 2.5.2.3 The 'urgent need to sequence lignin primary structure'; 2.5.3 Lignins' racemic nature; 2.5.3.1 The 'number of isomers' problem; 2.5.4 Comments on template replication; 2.5.5 Polymer branching; 2.6 Why the new hypothesis is not in contention; 2.7 Is lignification a biochemical anomaly? 327 $a2.7.1 Ferulate dehydrodimerization is combinatorial2.7.2 Polysaccharide primary structure is NOT absolutely dictated; 2.8 Summary comments on the dirigent/replication hypothesis; 2.9 Conclusions; 2.10 Notes; 2.11 References; Chapter 3 Flavonoid-Protein Binding Processes and their Potential Impact on Human Health; 3.1 Introduction; 3.2 Biologically relevant chemical properties of flavonoids; 3.3 Binding processes prior to absorption; 3.4 Binding processes involved in flavonoid bioavailability; 3.4.1 Absorption and conjugation; 3.4.2 Transport in plasma 327 $a3.4.3 Tissue distribution and cellular metabolism3.5 Binding processes involved in the potential health effects of flavonoids; 3.5.1 Inhibition of enzymes involved in ROS production; 3.5.2 Modulation of the redox properties of flavonoids by binding to proteins; 3.5.3 Inhibition of protein kinases; 3.5.4 Inhibition of cytochrome P450 enzymes; 3.5.5 Regulation of gene expression; 3.6 Conclusion; 3.7 References; Chapter 4 Methods for Synthesizing the Cocoa-Derived Oligomeric Epi-Catechins - Observations on the Anticancer Activity of the Cocoa Polyphenols; 4.1 Introduction 327 $a4.2 Synthesis of procyanidins 330 $aPolyphenols are the second most abundant class of substances in nature, and include tannins and flavonoids, many of which have extremely important antioxidant properties which have now been shown to have a key role in the prevention of cancer in humans. This important book covers polyphenol chemistry, biosynthesis and genetic manipulation, ecology and plant physiology, food and nutritional aspects and the effects of polyphenols on health. Included within the contents are cutting edge chapters on biotic and abiotic stress in plants, safety and toxicity in foods, functionality and nutraceutica 606 $aPolyphenols$xResearch 615 0$aPolyphenols$xResearch. 676 $a572/.2 701 $aDaayf$b Fouad$0310524 701 $aLattanzio$b Vincenzo$f1949-$074630 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910876890403321 996 $aRecent advances in polyphenol research$94195119 997 $aUNINA