LEADER 04905nam 2200601Ia 450 001 9910876800203321 005 20200520144314.0 010 $a1-280-72333-5 010 $a9786610723331 010 $a3-527-60849-4 010 $a3-527-60843-5 035 $a(CKB)1000000000377154 035 $a(EBL)482289 035 $a(OCoLC)609855574 035 $a(SSID)ssj0000294441 035 $a(PQKBManifestationID)11229843 035 $a(PQKBTitleCode)TC0000294441 035 $a(PQKBWorkID)10303818 035 $a(PQKB)10502455 035 $a(MiAaPQ)EBC482289 035 $a(EXLCZ)991000000000377154 100 $a20050509d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDynamics of the bacterial chromosome $estructure and function /$fWolfgang Schumann 210 $aWeinheim $cWiley-VCH ;$a[Chichester $cJohn Wiley, distributor]$dc2006 215 $a1 online resource (450 p.) 300 $aDescription based upon print version of record. 311 $a3-527-30496-7 320 $aIncludes bibliographical references and index. 327 $aDynamics of the Bacterial Chromosome; Contents; Foreword; Bacterial Species and their Abbreviation; Color Plates; 1 Structure of the Bacterial Cell; 1.1 The Cytoplasm Compartment; 1.2 The Cytoplasmic Membrane Compartment; 1.3 The Cell Wall Compartment; 1.4 The Outer Membrane Compartment; 1.5 The Periplasmic Compartment; 1.6 Extracellular Matrices; 1.7 Appendages; 2 Organization of the Bacterial Chromosome; 2.1 Structure of the Chromosomes; 2.2 Principles to Compact the Bacterial Chromosome; 2.2.1 Superhelicity; 2.2.2 Histone-like Proteins in E. coli 327 $a2.3 Organization of the Bacterial Chromosome into Genes and Repetitive Sequences2.3.1 Genes; 2.3.2 Repetitive Sequences; 2.4 Large Rearrangements Within the Chromosome; 2.4.1 Duplications; 2.4.2 Deletions; 2.4.3 Inversions; 3 The Bacterial Cell Cycle: Replication of the Chromosome, Partitioning and Cell Division; 3.1 Replication; 3.1.1 Replication of Circular Chromosomes; 3.1.2 Replication of Linear Chromosomes and Plasmids; 3.2 Partitioning (Segregation) of the Daughter Chromosomes; 3.3 Cell Division; 3.4 Plasmid- and Chromosome-encoded Toxin-Antitoxin Modules 327 $a3.4.1 Postsegregational Killing of Plasmid-free Cells3.4.2 Chromosomal Toxin-Antitoxins; 4 Recombination; 4.1 Homologous Recombination; 4.1.1 The RecBCD Pathway of Homologous Recombination; 4.1.2 The RecF Pathway of Homologous Recombination; 4.1.3 Additional Homologous Recombination Functions; 4.1.4 Recovery of Replication at a Blocking DNA Lesion; 4.2 Sequence-specific Recombination; 4.2.1 Integration/Excision Systems; 4.2.2 Resolvase Systems; 4.2.3 Inversion Systems; 4.2.4 Shufflons; 4.2.5 Integrons; 4.2.6 Homing Endonucleases; 4.3 Illegitimate Recombination 327 $a4.3.1 Insertion Sequence Elements4.3.2 Transposons; 4.3.3 Transposing Bacteriophages; 4.3.4 Mechanisms of Transposition; 4.3.5 Conjugative and Integrative Elements; 4.3.6 Nonhomologous Endjoining (NHEJ); 5 Origin of Mutations and Repair of DNA Lesions; 5.1 Classes of Mutations; 5.2 Origin of Mutations; 5.2.1 Spontaneous Mutations; 5.2.2 Induced Mutations; 5.2.3 Detection Systems for Mutations; 5.2.4 Adaptive Mutations; 5.3 Repair of DNA Lesions; 5.3.1 The Methyl-mediated Mismatch Repair System; 5.3.2 Very Short Patch Repair; 5.3.3 The Nucleotide Excision Repair Systems 327 $a5.3.4 Pathways of Base Excision Repair5.3.5 Repair of Oxidized Nucleotides; 5.3.6 Photoreactivation of Cyclobutane Dimers; 5.3.7 Transcription-coupled Nucleotide Excision Repair; 5.3.8 The Adaptive Response; 5.3.9 The SOS Response; 5.3.10 Replication and Repair; 5.3.11 Repair of Interstrand Crosslinks in DNA; 5.3.12 Deinococcus radiodurans; 6 Principles of Gene Regulation; 6.1 Regulation at the Level of DNA; 6.1.1 Alterations of the Structure of the DNA; 6.1.2 GATC Methylation and Gene Expression; 6.1.3 Programmed DNA Rearrangements Within the Chromosome 327 $a6.1.4 Transcriptional Silencing and Cryptic Genes 330 $aThis book provides an unique overview on bacterial genetics, bacterial genome projects and gene technology and its applications in biological and biomedical research and medicine. The author guides the reader up the front in research within the different fields of bacterial genetics, based mainly on results received with Escherichia coli and Bacillus subtilis. 606 $aBacterial genetics 606 $aBacterial genomes 615 0$aBacterial genetics. 615 0$aBacterial genomes. 676 $a579.3135 700 $aSchumann$b Wolfgang$cProf. Dr. rer. nat.$01757252 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910876800203321 996 $aDynamics of the bacterial chromosome$94195038 997 $aUNINA