LEADER 05324nam 2200661 a 450 001 9910876715803321 005 20200520144314.0 010 $a3-527-64206-4 010 $a1-283-30244-6 010 $a9786613302441 010 $a3-527-63274-3 010 $a3-527-63273-5 035 $a(CKB)3400000000000394 035 $a(EBL)700896 035 $a(OCoLC)758389527 035 $a(SSID)ssj0000506358 035 $a(PQKBManifestationID)11344040 035 $a(PQKBTitleCode)TC0000506358 035 $a(PQKBWorkID)10530064 035 $a(PQKB)11196378 035 $a(MiAaPQ)EBC700896 035 $a(EXLCZ)993400000000000394 100 $a20111128d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBiomechanics of hard tissues $emodeling, testing, and materials /$fedited by Andreas Ochsner and Waqar Ahmed 205 $a4th ed. 210 $aWeinheim [Germany] $cWiley-VCH Verlag GmbH & Co.$d2010 215 $a1 online resource (324 p.) 300 $aDescription based upon print version of record. 311 $a3-527-32431-3 320 $aIncludes bibliographical references and index. 327 $aBiomechanics of Hard Tissues: Modeling, Testing, and Materials; Contents; Preface; List of Contributors; 1 Bone and Cartilage - its Structure and Physical Properties; 1.1 Introduction; 1.1.1 The Structure of Living Organisms; 1.1.2 Growth of Living Organisms; 1.1.2.1 Ring-Shaped Grain Boundary; 1.1.3 Planarity of Biological Structures; 1.2 Macroscopic Structure of the Bone; 1.2.1 Growth of the Bone; 1.2.2 Structure of the Body; 1.2.3 Macroscopic Structure of Skeleton; 1.2.4 Apatite in the Bone; 1.2.5 Structure of the Bone; 1.3 Microscopic Structure of the Bone; 1.3.1 General; 1.3.2 Osteon 327 $a1.3.3 Bone Innervation1.3.3.1 Anatomy of Bone Innervation; 1.3.4 Bone Cells; 1.3.4.1 Cells; 1.3.4.2 Cell Membrane; 1.3.4.3 Membrane Transport; 1.3.4.4 Bone Cell Types; 1.3.4.5 Osteoclasts; 1.3.5 Cellular Image - OPG/RANK/RANKL Signaling System; 1.3.5.1 Osteoprotegerin; 1.3.5.2 RANK/RANKL; 1.3.5.3 TACE; 1.3.5.4 Bone Modeling and Remodeling; 1.3.6 Proteins and Amino Acids; 1.3.7 Collagen and its Properties; 1.3.7.1 Molecular Structure; 1.3.8 Geometry of Triple Helix; 1.3.9 Polymer Thermodynamics; 1.3.9.1 Thermodynamics; 1.3.9.2 Ideal Chain; 1.3.9.3 Wormlike Chain 327 $a1.3.9.4 Architecture of Biological Fibers1.3.9.5 Architecture of Collagen Fibers in Human Osteon; 1.3.9.6 Collagen Elasticity; 1.4 Remarks and Conclusions; 1.5 Comments; 1.6 Acknowledgments; References; Further Reading; 2 Numerical Simulation of Bone Remodeling Process Considering Interface Tissue Differentiation in Total Hip Replacements; 2.1 Introduction; 2.2 Mechanical Adaptation of Bone; 2.3 Constitutive Models; 2.3.1 Bone Constitutive Model; 2.3.2 Interface Constitutive Model; 2.3.3 Model for Periprosthetic Adaptation; 2.3.4 Model for Interfacial Adaptation; 2.4 Numerical Examples 327 $a2.5 Final Remarks2.6 Acknowledgments; References; 3 Bone as a Composite Material; 3.1 Introduction; 3.2 Bone Phases; 3.2.1 Organic; 3.2.2 Mineral; 3.2.3 Physical Structure of Bone Material; 3.2.4 Water; 3.3 Bone Phase Material Properties; 3.3.1 Organic Matrix; 3.3.2 Mineral Phase; 3.3.3 Water; 3.3.4 Elastic Modulus of Composite Materials; 3.4 Bone as a Composite: Macroscopic Effects; 3.5 Bone as a Composite: Microscale Effects; 3.6 Bone as a Composite: Anisotropy Effects; 3.7 Bone as a Composite: Implications; References 327 $a4 Mechanobiological Models for Bone Tissue. Applications to Implant Design4.1 Introduction; 4.2 Biological and Mechanobiological Factors in Bone Remodeling and Bone Fracture Healing; 4.2.1 Bone Remodeling; 4.2.2 Bone Fracture Healing; 4.3 Phenomenological Models of Bone Remodeling; 4.4 Mechanistic Models of Bone Remodeling; 4.5 Examples of Application of Bone Remodeling Models to Implant Design; 4.6 Models of Tissue Differentiation. Application to Bone Fracture Healing; 4.7 Mechanistic Models of Bone Fracture Healing 327 $a4.8 Examples of Application of Bone Fracture Healing Models to Implant Design 330 $aThis monograph assembles expert knowledge on the latest biomechanical modeling and testing of hard tissues, coupled with a concise introduction to the structural and physical properties of bone and cartilage. A strong focus lies on the current advances in understanding bone structure and function from a materials science perspective, providing practical knowledge on how to model, simulate and predict the mechanical behavior of bone. The book presents directly applicable methods for designing and testing the performance of artificial bones and joint replacements, while addressing innovative 606 $aHuman mechanics 606 $aMusculoskeletal system$xMechanical properties 606 $aBiomechanics 615 0$aHuman mechanics. 615 0$aMusculoskeletal system$xMechanical properties. 615 0$aBiomechanics. 676 $a617.47 701 $aOchsner$b Andreas$0317948 701 $aAhmed$b Waqar$0948864 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910876715803321 996 $aBiomechanics of hard tissues$94203514 997 $aUNINA