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024 7 $a10.1007/978-981-97-0511-5
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035   $a(DE-He213)978-981-97-0511-5
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100   $a20240705d2024      u|         0
101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aNon B cell-Derived Immunoglobulins $eThe Structure, Characteristics and the Implication on Clinical Medicine /$fedited by Xiaoyan Qiu, Jing Huang, Xiaojun Xu
205   $a1st ed. 2024.
210  1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024.
215   $a1 online resource (193 pages)
225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1445
311 08$aPrint version: Qiu, Xiaoyan Non B Cell-Derived Immunoglobulins Singapore : Springer Singapore Pte. Limited,c2024 9789819705108 
320   $aIncludes bibliographical references.
327   $aChapter 1 The history of appreciation of immunoglobulin and the discovery of non-B cell derived immunoglobulins -- Chapter 2 Expression profile of non B-Ig in different lineage cells -- Chapter 3 Unique V(D)J recombination characteristics and repertoire of non B-Ig -- Chapter 4 Unique regulation mechanismof non B-Ig gene -- Chapter 5 Unique structure and function of non B-Ig -- Chapter 6 Comparison of non B-Ig and B-Ig -- Chapter 7 Functionsand clinical relevanceof non-B cell derived immunoglobulin in liver -- Chapter 8 Significance of non-Bcell derived immunoglobulins in renal disease -- Chapter 9 Functions and clinical significance of myocardial cell-derived Immunoglobulins -- Chapter 10 Biological functions and clinical significance of intestinal non B-Immunoglobulins -- Chapter 11 Function of IgG and IgA in normal human skin -- Chapter 12 Significance of cancer-derived IgG in lung cancer -- Chapter 13 Significance of cancer-derived IgG in breast cancer -- Chapter 14 Significance of cancer-derived IgG in pancreatic cancer -- Chapter 15 Biological functions and clinical significance of non B-Ig in hemopoietic system.
330   $aThis book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.
410  0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1445
606   $aImmunology
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aLife sciences
606   $aImmunology
606   $aBiomedical Research
606   $aLife Sciences
606   $aBiomedical Research
615  0$aImmunology.
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615  0$aLife sciences.
615 14$aImmunology.
615 24$aBiomedical Research.
615 24$aLife Sciences.
615 24$aBiomedical Research.
676   $a616.0798
702   $aQiu$b Xiaoyan
702   $aHuang$b Jing
702   $aXu$b Xiaojun
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
912   $a9910872197703321
996   $aNon B cell-Derived Immunoglobulins$94238649
997   $aUNINA