LEADER 00918nam0-2200289 --450 001 9910745189303321 005 20231025132120.0 010 $a978-88-214-4066-3$bEdra 020 $aIT$b2016-7060 100 $a20231025d2016----kmuy0itay5050 ba 101 $aita$cspa 102 $aIT 105 $a 001yy 200 1 $aMalattie del cane e del gatto in età avanzata$ediagnosi e terapia$fSalvador Cervantes Sala$ga cura di Federico Fracassi 210 $aMilano$cEdra$aCremona$cEV$d2016 215 $aXX, 296 p.$cill.$d24 cm. 610 0 $aCani [e] Gatti$aMalattie 676 $a636.70896$v23 700 1$aCervantes Sala,$bSalvador$01431105 702 1$aFracassi,$bFederico 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a9910745189303321 952 $a636.0896 SAL1$b925$fFMVBC 959 $aFMVBC 996 $aMalattie del cane e del gatto in età avanzata$93572481 997 $aUNINA LEADER 08575nam 22006975 450 001 9910865279803321 005 20240531103958.0 010 $a3-031-55715-8 024 7 $a10.1007/978-3-031-55715-6 035 $a(MiAaPQ)EBC31359074 035 $a(Au-PeEL)EBL31359074 035 $a(CKB)32200391700041 035 $a(DE-He213)978-3-031-55715-6 035 $a(OCoLC)1443089323 035 $a(EXLCZ)9932200391700041 100 $a20240530d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Diabetic Foot $eMedical and Surgical Management /$fedited by Aristidis Veves, John M. Giurini, Marc L. Schermerhorn 205 $a5th ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2024. 215 $a1 online resource (589 pages) 225 1 $aContemporary Diabetes,$x2197-7844 311 08$a3-031-55714-X 327 $aClinical Features and Diagnosis.-Burden of Diabetic Foot -- Incidence, prevalence of foot ulceration -- Cost of foot ulceration -- The clinical examination of the diabetic foot and the identification of the at risk patient -- Clinical examination -- Screening techniques -- Classification of ulcers (Wagner and Texas classification and others in brief) -- (omit vascular examination) -- Diabetic neuropathy -- Epidemiology -- Classification -- Clinical features, main emphasis on sensorimotor neuropathy or other neuropathies of lower extremity -- Differential diagnosis -- Treatment -- Clinical features and diagnosis of peripheral arterial disease -- Pathogenesis -- Clinical features -- Diagnostic criteria -- Non-invasive methods, TcPO2, ABI -- Invasive methods -- Proposed algorithm, Reference to the ADA Consensus statement and PAD statement -- Radiographic changes of the diabetic foot -- Plain x-rays -- MRI -- Osteomyelitis diagnosis -- Differential diagnosis of osteomyelitis and Charcot -- MRI spectroscopy -- Principles of care in the diabetic surgical patient -- Control of DM in the surgical patient -- Role of intensive treatment -- Pathophysiology -- Pathophysiology of wound healing in chronic wounds -- Physiology of wound healing -- Pathophysiology of wound healing in DM -- Role of inflammation -- Role of angiogenesis under normal conditions -- Angiogenesis and Diabetes -- Pathophysiology of angiogenesis in the healing of the diabetic foot ulcer -- Factors that Affect Diabetic Wound Healing -- Neuropeptides and wound healing -- Mast cells -- PTP1B in wound healing -- Animal data vs human data: Similarities and differences -- Mechanisms of Vascular Disease in Diabetes -- Micro vs macrocirculation -- PAD in diabetes -- Role of microcirculation -- Omics, their role in understanding the diabetic lower extremity pathophysiology -- Skin Changes in the Diabetic Foot -- Dermatologic conditions Inflammation -- Biomechanics of the diabetic foot -- Foot anatomy related to biomechanics -- Gait Cycle -- Changes in diabetes (LJM, high foot pressures) -- Balance in diabetes -- Development of foot ulceration -- Methods to measure foot pressures -- Out of shoe methods -- In shoe methods -- Foot pressure measurements in diabetes -- Cell Therapies: New Frontier for the Management of Diabetic Foot Ulceration -- Limitations of currently available treatments -- Emerging new concepts -- Role of extracellular vesicles, modified mRNA, miRNA and siRNA in diabetic lower extremity complications -- New Biomaterials for the Management of the Diabetic Lower Extremity -- Microbiota of diabetic lower extremity -- Wound infection in diabetes -- Biomarkers of DFU and its healing progress -- Animal models of DFU -- Management of the Diabetic Foot -- Microbiology and Treatment of Diabetic Foot Infection -- Microbiology -- Algorithm of treatment -- Topical vs systemic treatment DFU assessment and wound preparation -- Topical Wound Care Treatment and indications for their use -- Role of dressings -- Selection of dressings, evidence-based evaluation -- Principles for using growth factors -- Review of tested all growth factors so far -- Review of VEGF and PDGF gene therapy clinical trials -- Emphasis on Regranex, the only commercially available growth factor: review of data, indications for using it in clinical practice -- Treatment according to ulcer stages -- Description of different LSE currently in clinical trials or available in clinical practice -- Review of data regarding diabetic foot studies -- Description of other topical, biologically active products -- Surgical Treatment of the Ulcerated Foot -- Lower Extremity Arterial Reconstruction in Patients with Diabetes Mellitus: Principles of Treatment -- Principles of treatment -- Brief description of surgical methods -- Outcomes of surgery -- Indications for angioplasty -- Brief description of angioplasty methods -- Outcomes of angioplasty -- Recommendations by recent guidelines -- We need numerous figures and pictures -- Reconstruction of the diabetic foot -- Reconstruction of diabetic foot -- Reconstruction of soft tissues of the Charcot foot -- Role of dermatomes -- Charcot Arthropathy in the Diabetic Foot -- Epidemiology -- Pathophysiology, stages of disease -- Microcirculation and development of Charcot -- Radiology -- Treatment -- Amputations and rehabilitation -- Major amputations, indications and description of basic principles -- Principles of rehabilitation -- Prostheses -- Organization and Preventive Care -- Organizationof the Diabetic Foot Care team -- Description of the DF care team -- Role of each specialty -- Flow diagram (gate keeper, communication between teams etc) -- Quality of Care -- Briefly describe current concepts of quality of care -- Quality of care of DF -- Comparative effectiveness -- Education and behavior modification at the at risk patient -- Psychological profile of the patient with DFU -- Impact of DFU on quality of life -- Techniques to modify behavior -- The role of foot wear in the prevention of diabetic foot problems -- Why we need proper footwear -- Review of studies regarding footwear -- General clinical recommendations. 330 $aThe fifth addition of this classic text that focuses on the diabetic foot continues the tradition of the previous four editions. More specifically, it includes contributions from a distinguished panel of clinicians and researchers, who have either participated in previous editions or are new, who provide up-to-date information on the pathophysiology and management of diabetic foot ulceration. As with the previous editions, it is divided into three sections: the first part focuses on clinical features and diagnosis; the second on pathophysiology; and the third on the management of diabetic foot problems. The main emphasis of the clinical part is on the multidisciplinary approach that has been mainly developed by the world-renowned Joslin-Beth Israel Deaconess Foot Center, which pioneered the management of diabetic lower extremity problems. Also like previous editions, the author panel includes diabetologists, podiatrists, vascular surgeons, infectious disease specialists, orthotists, plastic and orthopedic surgeons, the majority of whom work at the Joslin-Beth Israel Deaconess Foot Center. In addition, the fifth edition not only describes the state-of-the-art current methods in clinical practice but also includes a thorough update of all research progress during the last five years. This updated edition of this timely text will be of significant value to all physicians and researchers with interest in a comprehensive understanding of the diabetic foot. 410 0$aContemporary Diabetes,$x2197-7844 606 $aEndocrinology 606 $aOrthopedics 606 $aCardiology 606 $aSurgery 606 $aNeurology 606 $aEndocrinology 606 $aOrthopaedics 606 $aCardiology 606 $aSurgery 606 $aNeurology 615 0$aEndocrinology. 615 0$aOrthopedics. 615 0$aCardiology. 615 0$aSurgery. 615 0$aNeurology. 615 14$aEndocrinology. 615 24$aOrthopaedics. 615 24$aCardiology. 615 24$aSurgery. 615 24$aNeurology. 676 $a617.5/85 700 $aVeves$b Aristidis$01742437 701 $aGiurini$b John M$01742438 701 $aSchermerhorn$b Marc L$01742439 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910865279803321 996 $aThe Diabetic Foot$94169218 997 $aUNINA