LEADER 11956nam 22006615 450 001 9910865246303321 005 20250807145711.0 010 $a981-9977-15-0 024 7 $a10.1007/978-981-99-7715-4 035 $a(MiAaPQ)EBC31359061 035 $a(Au-PeEL)EBL31359061 035 $a(CKB)32200397200041 035 $a(DE-He213)978-981-99-7715-4 035 $a(OCoLC)1438671229 035 $a(EXLCZ)9932200397200041 100 $a20240530d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 12$aA Guide to Hormonal Dermatology /$fedited by Ramanjit Singh, Nidhi Sharma 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (177 pages) 311 08$a981-9977-17-7 311 08$a981-9977-14-2 327 $aIntro -- Foreword 1 -- Foreword 2 -- Preface -- Contents -- Chapter 1: Overview of Endocrinology -- 1.1 Disorder of the Hypothalamic-Pituitary Axis -- 1.1.1 Acromegaly -- 1.1.1.1 Dermatologic Manifestations -- 1.1.2 Hypopituitarism -- 1.2 Thyroid Related Disorders -- 1.2.1 Hyperthyroidism -- 1.2.1.1 Dermatological Manifestations -- 1.2.2 Hypothyroidism -- 1.2.2.1 Dermatological Manifestations -- 1.3 Disorders of the Adrenal Gland -- 1.3.1 Cushing Syndrome -- 1.3.1.1 Dermatologic Manifestations -- 1.3.2 Primary Adrenal Insufficiency -- 1.3.2.1 Dermatologic Manifestations -- Hyperpigmentation -- 1.3.3 Other Causes of Adrenal Insufficiency and Associated Skin Manifestations -- 1.3.3.1 Skin Manifestations -- 1.3.4 Pseudohypoaldosteronism -- 1.3.4.1 Dermatological Manifestations -- 1.4 Disorder of Parathyroid Hormone -- 1.4.1 Dermatological Manifestations -- 1.5 Disorder of the Endocrine Pancreas -- 1.5.1 Diabetes Mellitus -- 1.5.1.1 Dermatologic Manifestations -- 1.5.2 Glucagonoma -- 1.5.2.1 Dermatological Manifestations -- 1.6 Disorder of Androgen Excess -- 1.6.1 Polycystic Ovarian Syndrome -- 1.6.1.1 Dermatologic Manifestations -- 1.7 Hereditary Endocrine Syndromes -- 1.7.1 Multiple Endocrine Neoplasia (MEN) Syndromes -- 1.7.1.1 MEN1 -- 1.7.1.2 MEN 2 -- 1.8 Neurofibromatosis 1 -- 1.8.1 Skin Manifestations -- 1.9 Von Hippel Lindau -- 1.9.1 Skin Manifestations -- 1.10 Conclusion -- References -- Chapter 2: Obesity and Skin -- 2.1 Introduction -- 2.2 Effect of Obesity on Skin Pathophysiology -- 2.3 Common Skin Changes Associated with Obesity -- 2.3.1 Acanthosis Nigricans (AN) -- 2.3.2 Keratosis Pilaris -- 2.3.3 Achrocordons -- 2.3.4 Striae Distensae (SD) -- 2.3.5 Cellulite -- 2.3.6 Plantar Hyperkeratosis -- 2.3.7 Skin Infections -- 2.4 Rare Skin Conditions Associated with Obesity -- 2.4.1 Keratosis Follicularis Squamosa (Dohi -- KFS). 327 $a2.4.2 Adiposis Dolorosa/Dercum Disease (DD) -- 2.4.3 Granular Parakeratosis -- 2.4.4 Obesity Associated Lympedematous Mucinosis (OLAM) -- 2.5 Inflammatory Skin Diseases Associated with Obesity -- 2.5.1 Hidradenitis Suppurativa (HS) -- 2.5.2 Psoriasis -- 2.5.3 Rosacea -- 2.5.4 Hair and Scalp -- 2.5.5 Acne -- 2.5.6 Skin Malignancy -- 2.6 Conclusion -- References -- Chapter 3: Vitamin D and Skin -- 3.1 Introduction -- 3.2 Vitamin D and Its Synthesis -- 3.3 Functions of Vitamin D -- 3.4 Vitamin D Deficiency -- 3.5 Skin and Vitamin D -- 3.6 Mechanism of Action of Vitamin D -- 3.7 Atopic Dermatitis -- 3.8 Psoriasis -- 3.9 Vitiligo -- 3.10 Skin Cancers -- 3.11 Skin Pigmentation -- 3.12 Anti-aging -- 3.13 Other Skin Conditions -- 3.14 Vitamin D Dosing, Toxicity and Management -- 3.15 Conclusion -- References -- Chapter 4: Thyroid Disorders and the Skin -- 4.1 Introduction -- 4.2 Thyroid Gland -- 4.2.1 Anatomy -- 4.2.2 Embryology -- 4.2.3 Hormones -- 4.3 Thyroid Diseases -- 4.3.1 Laboratory Diagnosis -- 4.3.2 Types and Epidemiology -- 4.3.3 Hyperthyroidism -- 4.3.4 Hypothyroidism -- 4.4 Thyroid Cancer -- 4.5 Alopecia Areata -- 4.6 Chronic Idiopathic Urticaria -- 4.7 Other Thyroid Dermopathies -- 4.8 Dermatitis Herpetiformis -- 4.9 Vitiligo -- 4.10 Psoriasis -- 4.11 Miscellaneous Diseases -- 4.12 Conclusion -- References -- Chapter 5: Cutaneous Manifestations of Diabetes -- 5.1 Introduction -- 5.2 Pathogenesis -- 5.3 Cutaneous Manifestations Associated with Complications of Diabetes (Vascular and Neurological Damage) -- 5.3.1 Diabetic Dermopathy -- 5.3.2 Rubeosis Faciei -- 5.3.3 Palmar Erythema -- 5.3.4 Periungual Telangiectasias -- 5.3.5 Diabetic Foot Syndrome -- 5.3.6 Pigmented Purpuric Dermatoses -- 5.4 Cutaneous Infections in Diabetes Mellitus -- 5.4.1 Bacterial Infections -- 5.4.2 Fungal Infections. 327 $a5.5 Skin Diseases Associated with Insulin Resistance, Obesity and Metabolic Syndrome (Table 5.5) -- 5.5.1 Acanthosis Nigricans -- 5.5.2 Eruptive Xanthomas (EX) -- 5.5.3 Acrochordons -- 5.6 Skin Manifestations Associated with Diabetes -- 5.6.1 Granulomatous Disorders -- 5.6.2 Stiff Skin and Joints -- 5.6.3 Bullosis Diabeticorum -- 5.6.4 Acquired Perforating Dermatosis -- 5.6.5 Other Miscellaneous Disorders -- 5.7 Cutaneous Changes Associated with Diabetes Medications (Table 5.6) -- 5.7.1 Insulin -- 5.7.2 Oral Medications -- References -- Chapter 6: Pathophysiology of PCOS -- 6.1 Introduction -- 6.2 Definition of PCOS -- 6.3 Phenotypes -- 6.4 Pathophysiology of PCOS -- 6.5 Factors Drive to PCOS (Fig. 6.2) -- 6.6 Conclusion -- References -- Chapter 7: PCOS Investigations and Clinical Implications -- 7.1 Definition of PCOS -- 7.2 Diagnostic Criteria Changing with Time -- 7.3 Diagnosis of PCOS: AACE/ACE2015 -- 7.4 What About Other Tests -- 7.5 Anti Mullerian Hormone (AMH) -- 7.6 Serum 3?-Diol G: As a Marker for Idiopathic Hirsutism (IH), PCOS with Hirsutism -- 7.6.1 Alpha 3 Diol in Adult Acne -- 7.6.2 Other Features of PCOS: Not Included in the Diagnostic Criteria -- 7.6.3 Abnormal Gonadotrophin Secretion Measurements -- 7.6.4 Summary and Key Points in Diagnosis of PCOS -- References -- Chapter 8: PCOD-Management of ACNE -- 8.1 Introduction -- 8.2 Management -- 8.2.1 Non-hormonal Therapy -- 8.2.2 Oral Isotretinoin -- 8.2.3 Oral Antibiotics -- 8.2.3.1 Hormonal Therapy -- 8.2.4 Combined Oral Contraceptives -- 8.2.5 Spironolactone -- 8.2.6 Androgen Receptor Blockers -- 8.2.6.1 Cyproterone Acetate -- 8.2.6.2 Flutamide -- 8.2.6.3 Insulin-Sensitizing Agents -- 8.2.6.4 Psychological Support -- References -- Chapter 9: Management of Pigmentation in Polycystic Ovary Syndrome -- 9.1 Introduction -- 9.2 Acanthosis Nigricans -- 9.2.1 Treatment. 327 $a9.2.1.1 General Counselling -- 9.2.1.2 Topical Medications -- 9.2.1.3 Systemic Medications -- 9.2.1.4 In-Clinic Treatment -- 9.3 Hyperprolactinemia -- 9.3.1 Treatment -- 9.3.1.1 Systemic Medications -- 9.3.1.2 Pro Tip -- 9.4 Seborrheic Dermatitis -- 9.4.1 Treatment -- 9.4.1.1 General Instruction -- 9.4.1.2 Topicals -- 9.4.1.3 Systemic Medications -- 9.4.1.4 In-Clinic Treatment -- 9.5 Post Acne PIH -- 9.5.1 Treatment -- 9.5.1.1 General Instructions -- 9.5.1.2 Topical Therapy -- 9.5.1.3 Oral Drugs -- 9.5.1.4 Pro Tip -- 9.5.1.5 In-Clinic Treatments -- 9.5.1.6 Lasers and EBD -- 9.6 DPN/Acrochordans -- 9.7 Melasma -- 9.7.1 General Instructions -- 9.7.2 Topical Treatment -- 9.7.3 In-Clinic Treatment -- 9.7.4 Lasers and EBD -- 9.8 Laser Induced Hyperpigmentation -- 9.8.1 Treatment -- 9.8.1.1 General Care -- 9.8.1.2 Topical Therapy -- 9.8.1.3 Oral Treatment -- 9.8.1.4 In-Clinic Treatment -- 9.9 Conclusion -- References -- Chapter 10: Management of Hirsutism in PCOS -- 10.1 Introduction -- 10.1.1 Causes -- 10.1.2 Evaluation -- 10.1.3 Examination -- 10.2 Treatments -- 10.2.1 General Care -- 10.2.2 Topical Treatment -- 10.2.3 Oral Treatment -- 10.2.3.1 Myoinostiol -- 10.2.3.2 Oral Contraceptive Pills -- 10.3 Anti Androgens -- 10.3.1 Cyproterone Acetate [24] -- 10.3.2 Spironolactone -- 10.3.3 Flutamide/Bicalutamide [27] -- 10.3.4 Finasteride/Dutasteride -- 10.3.4.1 Glucocorticoids -- 10.3.4.2 GnRH Analogues -- 10.3.4.3 Insulin Sensitizers -- 10.3.4.4 Antifungal Agents -- 10.3.5 Alternative Therapies [31] -- 10.4 In-Clinic Treatment -- 10.4.1 Electrolysis [32] -- 10.4.2 Lasers and Lights -- 10.4.3 Mechanisms of Lasers -- 10.5 Conclusion -- References -- Chapter 11: PCOS-Management of Androgenetic Alopecia -- 11.1 Introduction -- 11.1.1 Pathogenesis -- 11.2 Investigations -- 11.3 Management -- 11.3.1 5 Alpha-Reductase Inhibitors -- 11.3.1.1 Finasteride. 327 $a11.3.1.2 Dutasteride -- 11.3.2 Cyproterone Acetate -- 11.4 Minoxidil -- 11.5 Topical Therapy -- 11.5.1 Minoxidil -- 11.6 Lasers and Light Treatments -- 11.7 Invasive Procedures -- 11.7.1 Platelet Rich Plasma Therapy -- 11.8 Microneedling -- 11.9 Hair Transplantation -- 11.10 Cosmetic Camouflage -- 11.11 Conclusion -- References -- Chapter 12: Counselling in Hair Transplant Patient -- 12.1 Introduction -- 12.2 Part 1: Basics of Hair Transplant -- 12.2.1 Section 1: Types of Hair Transplant -- 12.2.1.1 Beard, Eyebrow and Eyelash Transplant -- 12.2.2 Section 2: Procedure of Hair Transplant -- 12.2.2.1 Hairline Design Depends on -- 12.2.2.2 Theory of Safe Donor Zone in FUE [9] -- 12.2.2.3 Principles of Implantation -- 12.2.3 Implantation Techniques: (Refer Table 12.3) -- 12.2.4 Comprehensive Procedure Protocol -- 12.2.5 Advantages of CPP -- 12.2.6 Section 3: Benefits and Risks of Hair Transplant -- 12.2.6.1 Benefits of Hair Transplant -- 12.2.6.2 Possible Risks and Complications -- 12.3 Part 2: Consultation -- 12.3.1 Section 1: Purpose of Consultation -- 12.3.1.1 Importance of Consultation for Hair Transplant by a Specialist -- 12.3.1.2 Patient Selection -- 12.3.1.3 How to Manage Unhappy or Difficult Patients -- 12.3.1.4 What to Expect from a Consultation for Hair Transplant by a Specialist -- 12.3.2 Section 2: Components of Consultation -- 12.3.2.1 Hamilton-Norwood Classification -- 12.3.2.2 During the Consultation -- 12.3.2.3 During the Pre-Operative Stage -- 12.3.2.4 During the Surgery (Refer Fig. 12.7) -- 12.3.2.5 In the Post-Operative Stage -- 12.3.2.6 Summary Points to Be Followed for Better Consultation -- References -- Chapter 13: Importance of Nutrition & -- Diet in PCOS -- 13.1 Introduction -- 13.1.1 Physiological Basis -- 13.2 Role of Gut Microbiome -- 13.2.1 Oxidative Stress and Chronic Inflammation -- 13.3 Dietary Patterns and PCOS. 327 $a13.3.1 Mediterranean Diet. 330 $aThis book covers all aspects of how various Hormonal diseases affect Skin Health. It covers essential parts of the most common Hormonal disease - Polycystic Ovarian Disease (PCOD), i.e., its Pathogenesis, investigations, and individual clinical features with their Line of management. Chapters also provide information about other common yet less discussed hormonal issues like- Diabetes, Thyroid disease, and obesity affecting the skin and what signs and symptoms should be looked for in such patients for early diagnosis and treatment. Hence, this book assists Dermatologists, Consulting Physicians, Post Graduates, and Interns in a holistic understanding and practical management of standards as well as other miscellaneous issues like Diet and Hormones and Urticaria and Hormones. 606 $aDermatology 606 $aDiseases 606 $aInternal medicine 606 $aDermatology 606 $aDiseases 606 $aInternal Medicine 615 0$aDermatology. 615 0$aDiseases. 615 0$aInternal medicine. 615 14$aDermatology. 615 24$aDiseases. 615 24$aInternal Medicine. 676 $a616.5 700 $aSingh$b Ramanjit$01742774 701 $aSharma$b Nidhi$01103366 701 $aLotti$b Torello$01742775 701 $aTrehan$b Naresh$01742776 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910865246303321 996 $aA Guide to Hormonal Dermatology$94169452 997 $aUNINA