LEADER 04165nam 22006255 450 001 9910864196503321 005 20250807130355.0 010 $a3-031-54960-0 024 7 $a10.1007/978-3-031-54960-1 035 $a(MiAaPQ)EBC31353405 035 $a(Au-PeEL)EBL31353405 035 $a(CKB)32142956700041 035 $a(DE-He213)978-3-031-54960-1 035 $a(OCoLC)1435802720 035 $a(EXLCZ)9932142956700041 100 $a20240523d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCardiovascular Outcomes Research $eA Clinician?s Guide to Cardiovascular Epidemiology and Clinical Outcomes Trials /$fedited by Kevin C. Maki, Don P. Wilson 205 $a1st ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2024. 215 $a1 online resource (446 pages) 225 1 $aContemporary Cardiology,$x2196-8977 311 08$a3-031-54962-7 311 08$a3-031-54959-7 327 $aChapter 1. History of Cardiovascular Epidemiology -- Chapter 2. Types of Cardiovascular Outcomes Studies -- Chapter 3. Basic Statistical Considerations for Cardiovascular Outcomes Studies -- Chapter 4. Evolving Concepts in Cardiovascular Outcomes Studies -- Chapter 5. Current Guidelines for Atherosclerotic Cardiovascular Disease Risk Reduction -- Chapter 6. Surrogate Markers of Cardiovascular Disease -- Chapter 7. Challenges in Developing Evidence-based Recommendations for Non-pharmacological Interventions for Atherosclerotic Cardiovascular Disease Risk Reduction -- Chapter 8. Overview of the Pharmaceutical Development Process for Agents to Influence Cardiovascular Health -- Chapter 9. Lipids and Cardiovascular Outcomes -- Chapter 10. Inflammation and Cardiovascular Outcomes -- Chapter 11. Hemostasis and Cardiovascular Outcomes -- Chapter 12. Cardiac Rhythms and Cardiovascular Outcomes -- Chapter 13. Blood Pressure and CardiovascularOutcomes -- Chapter 14. Diabetes, Obesity, Metabolic Syndrome and Cardiovascular Outcomes -- Chapter 15. Chronic Kidney Disease and Cardiovascular Outcomes. . 330 $aThis book provides clinicians with the information needed to effectively interpret the literature from observational and interventional cardiovascular outcomes studies. The book begins by providing a historical context of cardiovascular epidemiology, followed by chapters addressing key concepts in the study of cardiovascular disease such as the types of cardiovascular outcomes studies, basic and evolving design and statistical considerations, current guidelines for reducing atherosclerotic cardiovascular disease risk, surrogate markers of cardiovascular disease, challenges in developing evidence-based recommendations for non-pharmacological interventions, an overview of the pharmaceutical development process, and a detailed discussion of the clinical evidence supporting several factors and their relationships with atherosclerotic cardiovascular disease (lipids, inflammation, hemostasis, heart rhythm, blood pressure, diabetes, obesity, and chronic kidney disease). Cardiovascular Outcomes Research is a must-have resource for physicians and other clinicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention. . 410 0$aContemporary Cardiology,$x2196-8977 606 $aCardiology 606 $aEpidemiology 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCardiology 606 $aEpidemiology 606 $aBiomedical Research 615 0$aCardiology. 615 0$aEpidemiology. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 14$aCardiology. 615 24$aEpidemiology. 615 24$aBiomedical Research. 676 $a616.12 700 $aMaki$b Kevin C$01729521 701 $aWilson$b Don P$01741037 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910864196503321 996 $aCardiovascular Outcomes Research$94166962 997 $aUNINA