LEADER 02905nam 22006615 450 001 9910861088803321 005 20250320005240.0 010 $a9783031563379 010 $a3031563379 024 7 $a10.1007/978-3-031-56337-9 035 $a(MiAaPQ)EBC31343096 035 $a(Au-PeEL)EBL31343096 035 $a(CKB)32063316200041 035 $a(DE-He213)978-3-031-56337-9 035 $a(OCoLC)1434591481 035 $a(EXLCZ)9932063316200041 100 $a20240515d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHierarchical Archimedean Copulas /$fby Jan Górecki, Ostap Okhrin 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (128 pages) 225 1 $aSpringerBriefs in Applied Statistics and Econometrics,$x2524-4124 311 08$a9783031563362 311 08$a3031563360 327 $aPreface -- 1 Copulas -- 2 Archimedean Copulas -- 3 Construction -- 4 Properties -- 5 Sampling -- 6 Estimation -- 7 Temporal Models and their Applications -- 8 Software. 330 $aThis book offers a thorough understanding of Hierarchical Archimedean Copulas (HACs) and their practical applications. It covers the basics of copulas, explores the Archimedean family, and delves into the specifics of HACs, including their fundamental properties. The text also addresses sampling algorithms, HAC parameter estimation, and structure, and highlights temporal models with applications in finance and economics. The final chapter introduces R, MATLAB, and Octave toolboxes for copula modeling, enabling students, researchers, data scientists, and practitioners to model complex dependence structures and make well-informed decisions across various domains. 410 0$aSpringerBriefs in Applied Statistics and Econometrics,$x2524-4124 606 $aStatistics 606 $aStatistics 606 $aProbabilities 606 $aStatistics$xComputer programs 606 $aStatistical Theory and Methods 606 $aStatistics in Business, Management, Economics, Finance, Insurance 606 $aProbability Theory 606 $aStatistical Software 615 0$aStatistics. 615 0$aStatistics. 615 0$aProbabilities. 615 0$aStatistics$xComputer programs. 615 14$aStatistical Theory and Methods. 615 24$aStatistics in Business, Management, Economics, Finance, Insurance. 615 24$aProbability Theory. 615 24$aStatistical Software. 676 $a519.5 700 $aGórecki$b Jan$0561289 701 $aOkhrin$b Ostap$0767448 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910861088803321 996 $aHierarchical Archimedean Copulas$94163261 997 $aUNINA LEADER 05973nam 2200853Ia 450 001 9910139751303321 005 20200520144314.0 010 $a9786612278525 010 $a9781282278523 010 $a1282278525 010 $a9780470475973 010 $a0470475978 010 $a9780470475966 010 $a047047596X 035 $a(CKB)1000000000790452 035 $a(EBL)455914 035 $a(OCoLC)441892212 035 $a(SSID)ssj0000338203 035 $a(PQKBManifestationID)11292566 035 $a(PQKBTitleCode)TC0000338203 035 $a(PQKBWorkID)10312431 035 $a(PQKB)10694027 035 $a(MiAaPQ)EBC455914 035 $a(Au-PeEL)EBL455914 035 $a(CaPaEBR)ebr10333003 035 $a(CaONFJC)MIL227852 035 $a(OCoLC)286483826 035 $a(FINmELB)ELB178390 035 $a(Perlego)2768757 035 $a(EXLCZ)991000000000790452 100 $a20090421d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGlutathione and sulfur amino acids in human health and disease /$fRoberta Masella and Giuseppe Mazza 205 $a1st ed. 210 $aHoboken $cWiley$dc2009 215 $a1 online resource (626 p.) 300 $aDescription based upon print version of record. 311 08$a9780470170854 311 08$a0470170859 327 $aGLUTATHIONE AND SULFUR AMINO ACIDS IN HUMAN HEALTH AND DISEASE; CONTENTS; PREFACE; CONTRIBUTORS; I INTRODUCTION; 1 GLUTATHIONE AND THE SULFUR-CONTAINING AMINO ACIDS: AN OVERVIEW; 1.1 Introduction; 1.2 Why Sulfur-Containing Amino Acids?; 1.3 S-Adenosylmethionine, Nature's Wonder Cofactor; 1.4 Glutathione; 1.5 Taurine-the Second Essential Sulfur-Containing Amino Acid?; 1.6 Conclusions; Acknowledgments; References; II CHEMISTRY AND METABOLISM OF GSH AND SULFUR AMINO ACIDS; 2 SULFUR AMINO ACIDS CONTENTS OF DIETARY PROTEINS: DAILY INTAKE AND REQUIREMENTS; 2.1 Introduction 327 $a2.2 Sulfur Amino Acids (SAA) Content of Dietary Protein2.3 Sulfur Amino Acid Intake; 2.4 Nutritional Requirement for Total Sulfur Amino Acids; 2.5 Conclusions; References; 3 CELLULAR COMPARTMENTALIZATION OF GLUTATHIONE; 3.1 Introduction; 3.2 Glutathione Content in Cells; References; 4 INTESTINAL METABOLISM OF SULFUR AMINO ACIDS; 4.1 Introduction; 4.2 Isotopic Approaches to Study Metabolism; 4.3 Evidence of Gut Sulfur Amino Acid Metabolism; 4.4 Other Key Players in Intestinal Sulfur Amino Acid Metabolism; 4.5 Cysteine in Redox Function and Oxidant Stress in the Gut 327 $a4.6 Pathophysiology of Sulfur Amino Acid Metabolism in the GIT4.7 Conclusions; References; 5 HEPATIC SULFUR AMINO ACID METABOLISM; 5.1 Introduction; 5.2 Dietary Relation between Methionine and Cysteine; 5.3 Metabolic Relation between Hepatic Sulfur Amino Acids, B Vitamins, and Methyl Group Metabolism; 5.4 Regulation of Sulfur Amino Acid Metabolism and Related Metabolic Pathways in the Liver; 5.5 Impact of Physiologic and Nutritional Factors on Sulfur Amino Acid Metabolism; 5.6 Conclusions; References; III ANTIOXIDANT AND DETOXIFICATION ACTIVITIES 327 $a6 GLUTATHIONE AND SULFUR CONTAINING AMINO ACIDS: ANTIOXIDANT AND CONJUGATION ACTIVITIES6.1 Introduction; 6.2 Reactive Oxygen Species and Antioxidants; 6.3 Glutathione Redox Cycle; 6.4 Regulation of GSH and Cysteine Levels; 6.5 Biotransformation; 6.6 ROS-Mediated Cellular Signaling; 6.7 Transcription Regulation of Antioxidant and Conjugation Enzymes; 6.8 Oxidative Stress and Diseases; References; 7 GLUTAREDOXIN AND THIOREDOXIN ENZYME SYSTEMS: CATALYTIC MECHANISMS AND PHYSIOLOGICAL FUNCTIONS; 7.1 Introduction; 7.2 General Characteristics of Glutaredoxins 327 $a7.3 General Characteristics of Thioredoxins7.4 Glutaredoxin Mechanism of Action; 7.5 Thioredoxin Mechanism of Action; 7.6 Control of Grx Expression; 7.7 Control of Trx Expression in Mammalian Systems; 7.8 Cellular Functions of Grx; 7.9 Cellular Functions of Trx; 7.10 Reversible Sulfhydryl Oxidation and Disease; 7.11 Conclusions; References; 8 METHIONINE SULFOXIDE REDUCTASES: A PROTECTIVE SYSTEM AGAINST OXIDATIVE DAMAGE; 8.1 Introduction; 8.2 History of the Msr System; 8.3 MsrA and MsrB Protein Structure and Mechanism of Action; 8.4 Msr Reducing Requirement; 8.5 Other Members of the Msr Family 327 $a8.6 The Msr System: Both a Repair Enzyme and a Scavenger of ROS 330 $aThe complex roles of glutathione and sulfur amino acids in human health Glutathione (?-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease 606 $aGlutathione$xPsychological aspects 606 $aSulfur amino acids$xPsychological aspects 606 $aGlutathione$xTherapeutic use 606 $aSulfur amino acids$xTherapeutic use 606 $aGlutathione$xMetabolism 606 $aSulfur amino acids$xMetabolism 615 0$aGlutathione$xPsychological aspects. 615 0$aSulfur amino acids$xPsychological aspects. 615 0$aGlutathione$xTherapeutic use. 615 0$aSulfur amino acids$xTherapeutic use. 615 0$aGlutathione$xMetabolism. 615 0$aSulfur amino acids$xMetabolism. 676 $a612.015756 676 $a612.3/98 676 $a612.398 700 $aMasella$b Roberta$0887523 701 $aMazza$b G.$f1946-$0887524 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139751303321 996 $aGlutathione and sulfur amino acids in human health and disease$91982646 997 $aUNINA