LEADER 04589nam 22006255 450 001 9910847590003321 005 20240404085751.0 010 $a981-9983-65-7 024 7 $a10.1007/978-981-99-8365-0 035 $a(MiAaPQ)EBC31267066 035 $a(Au-PeEL)EBL31267066 035 $a(CKB)31405585900041 035 $a(MiAaPQ)EBC31252745 035 $a(Au-PeEL)EBL31252745 035 $a(DE-He213)978-981-99-8365-0 035 $a(EXLCZ)9931405585900041 100 $a20240403d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aExtracellular Vesicles$b[electronic resource] $eFrom Bench to Bedside /$fedited by Qian Wang, Lei Zheng 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (586 pages) 311 $a981-9983-64-9 327 $aSection 1 EVs biology and function -- Classification and nomenclature of extracellular vesicles -- EVs biogenesis and function -- The mechanism of interaction between extracellular vesicles and target cells -- Biological functions of EVs in various systems -- The role and mechanism of EVs in the process of disease -- Section 2 Technologies and methods for EVs research -- Methods for EV isolation, purification and characterization -- Technologies for the analysis of EV omics -- Flow cytometry for single EV analysis -- Microfluidics-based technologies for EVs research -- Biosensing Technologies for EVs detection -- Technology for EVs surface functionalization -- Technologies for visualization and tracking of EVs -- Methods for EVs function research -- Chemical Biology Investigation of Extracellular Vesicles -- Section 3 EVs biomarker in diseases -- EV biomarker screening and clinical verification -- EVs biomarker for cancer -- EVs biomarker for disease diagnosis -- EVs biomarker for immune disorder -- EVs biomarker for neurological diseases -- EVs biomarker for infectious disease -- EVs biomarker for renal diseases -- EVs biomarker for thrombosis -- Section 4 EVs for disease therapy and prevention -- Stem cell-derived EVs for disease therapy -- EVs in cancer immunotherapy -- Platelet-derived EVs in disease therapy -- Plant-derived Extracellular Nanovesicles for Disease Therapy -- EVs engineering for therapy -- Other EVs for disease therapy -- EV-based clinical trial -- Section 5 Introduction to the guidelines and resources for EV research -- Introduction to the guidelines for EV research -- Introduction to online nucleic acid database for EV research -- Introduction of systems biology in EV. 330 $aThis book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy. 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCytology 606 $aBiological transport 606 $aCell membranes 606 $aTranslational Research 606 $aCell Biology 606 $aMembrane Trafficking 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aCytology. 615 0$aBiological transport. 615 0$aCell membranes. 615 14$aTranslational Research. 615 24$aCell Biology. 615 24$aMembrane Trafficking. 676 $a571.655 700 $aWang$b Qian$01379301 701 $aZheng$b Lei$01595594 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910847590003321 996 $aExtracellular Vesicles$94156230 997 $aUNINA