LEADER 03118nam 22005535 450 001 9910847587203321 005 20240409125106.0 010 $a3-031-41777-1 024 7 $a10.1007/978-3-031-41777-1 035 $a(CKB)31403846400041 035 $a(MiAaPQ)EBC31267321 035 $a(Au-PeEL)EBL31267321 035 $a(DE-He213)978-3-031-41777-1 035 $a(EXLCZ)9931403846400041 100 $a20240409d2024 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aStroke Genetics$b[electronic resource] /$fedited by Pankaj Sharma, James F. Meschia 205 $a3rd ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2024. 215 $a1 online resource (626 pages) 311 $a3-031-41776-3 327 $aIntroduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics. 330 $aThis revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined in the field of inherited stroke. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge. 606 $aNeurology 606 $aInternal medicine 606 $aMedical genetics 606 $aNeurology 606 $aInternal Medicine 606 $aMedical Genetics 615 0$aNeurology. 615 0$aInternal medicine. 615 0$aMedical genetics. 615 14$aNeurology. 615 24$aInternal Medicine. 615 24$aMedical Genetics. 676 $a616.81042 700 $aSharma$b Pankaj$0769368 701 $aMeschia$b James F$01643698 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910847587203321 996 $aStroke Genetics$94156210 997 $aUNINA