LEADER 12611nam 22006375 450 001 9910845486703321 005 20240324160520.0 010 $a3-031-52603-1 024 7 $a10.1007/978-3-031-52603-9 035 $a(MiAaPQ)EBC31225662 035 $a(Au-PeEL)EBL31225662 035 $a(DE-He213)978-3-031-52603-9 035 $a(CKB)31056854900041 035 $a(EXLCZ)9931056854900041 100 $a20240321d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMusculoskeletal Injections Manual$b[electronic resource] $eBasics, Techniques and Injectable Agents /$fedited by Baris Kocaoglu, Lior Laver, Laura de Girolamo, Riccardo Compagnoni 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2024. 215 $a1 online resource (213 pages) 311 $a3-031-52602-3 327 $aIntro -- Preface -- Contents -- Part I: Basics of Musculoskeletal Injections -- 1: Philosophy of Musculoskeletal Injections -- 1.1 Introduction -- 1.2 Philosophy of Musculoskeletal Injections -- 1.3 Conclusion -- References -- 2: The Evidence-Based Medicine for Injection Therapy -- 2.1 Introduction -- 2.2 Intra-Articular Injections -- 2.3 Extra-Articular Injections -- 2.4 Conclusion -- References -- 3: Contraindications and Potential Side Effects of Injections -- 3.1 Introduction -- 3.2 Intra-Articular Effects -- 3.3 Surrounding Tissue Effects -- 3.4 Systemic Effects -- 3.5 Conclusion -- References -- 4: Informing Patients -- 4.1 Possible Complications of Injections -- 4.2 Obtaining Consent from the Patient -- References -- 5: Sterilization and Injection Materials -- 5.1 Introduction -- 5.2 Injection Equipment -- 5.3 Preparation of Injection Site -- References -- 6: Things to Take into Consideration in Injection and Aspiration -- 6.1 Indication for Treatment -- 6.2 Settings -- 6.3 Medical History -- 6.4 Anatomical Landmarks -- 6.5 Minimize Risk of Infection -- 6.6 The Procedure -- 6.7 Conclusion -- References -- 7: Postinjection Care and Education -- 7.1 Introduction -- 7.2 Immediate Aftercare -- 7.3 Dressing -- 7.4 Pressure and Cooling -- 7.5 Mobilization and Return to Activity -- 7.6 Postinjection Pain: General Complications -- 7.7 Postinjection Pain: Local Complications -- 7.8 Elective Surgery after Injection -- 7.9 Conclusion -- References -- Part II: Non Biologic Agents for Injections -- 8: Corticosteroids and Local Anesthetics -- 8.1 Background -- 8.1.1 Corticosteroids (CS) -- 8.1.2 Local Anesthetics (LA) -- 8.2 An Overview of the Indications -- 8.3 Contraindications -- 8.4 Complications -- 8.5 Applications of Corticosteroids and Local Anesthetic in the Knee Joint -- 8.6 Conclusion -- References. 327 $a9: Viscosupplementation Agents -- 9.1 Background -- 9.2 Mechanism of Action -- 9.3 Viscosupplementation Agents -- 9.4 Contraindications and Adverse Events -- 9.5 Evidence -- 9.6 Joint-Based Applications -- 9.6.1 Shoulder -- 9.6.2 Ankle -- 9.6.3 Knee -- 9.6.4 Hip -- 9.6.5 Hand -- 9.7 Conclusion -- References -- 10: Radiosynovectomy -- 10.1 Introduction -- 10.2 Indications and Contraindications of Radiosynovectomy -- 10.3 Informed Concept and Procedure -- 10.3.1 Joints Specific Approaches and Needle Sizes for RSV -- 10.3.2 RSV in Rheumatoid Arthritis -- 10.3.3 RSV in Hemophilia -- 10.3.4 RSV in Osteoarthritis -- 10.4 Conclusion -- References -- 11: Deproteinized Hemoderivative of Calf Blood-Natural Botanical and Mineral Extracts -- 11.1 Introduction -- 11.2 Most Used Deproteinized Hemoderivative of Calf Blood-Natural Botanical and Mineral Extracts -- 11.3 Conclusion -- References -- Part III: Ortho-biologic Agents for Injections -- 12: Orthobiologics: Background -- 12.1 Introduction -- 12.2 Types and Effects of Orthobiologics -- 12.3 Conclusion -- References -- 13: Platelet-Rich Plasma for Osteoarthritis -- 13.1 Introduction -- 13.2 PRP Outcomes for OA -- 13.3 Application Protocol -- 13.4 Conclusion -- References -- 14: Platelet-Rich Plasma Treatment for Meniscal Tears -- 14.1 The Anatomy of the Menisci -- 14.2 Meniscal Injuries and Rationale for Use of PRP -- 14.3 PRP Use for Meniscal Tears: Clinical Data -- 14.4 Conclusion -- References -- 15: PRP in Tendinopathy -- 15.1 Introduction -- 15.2 Fundamentals of PRP in Tendinopathy -- 15.3 Role of Leukocytes in the Treatment of Tendinopathies with PRP -- 15.4 Leukocyte-Rich PRP and Leukocyte-Poor PRP in Tendinopathy -- 15.5 Importance of the Activation of the Inflammatory Process in the Use of PRP -- 15.6 Conclusion -- References. 327 $a16: Platelet-Rich Plasma (PRP) for Rotator Cuff Tears -- 16.1 Introduction -- 16.2 Healing Rotator Cuff Injuries with PRP Therapy -- 16.3 The Effectiveness of PRP for Rotator Cuff Tears -- 16.3.1 PRP Injections as Isolated Treatment for Rotator Cuff Tears -- 16.3.2 PRP as an Adjunct to Rotator Cuff Repairs -- 16.3.3 Effects on the Rotator Cuff's Structural Integrity -- 16.4 Discussion -- 16.5 Conclusion -- References -- 17: Platelet-Rich Plasma Treatment for Muscle Injuries -- 17.1 Introduction -- 17.2 Muscle Healing Pathophysiology and Rationale for Using PRP -- 17.3 Platelet-Rich Plasma for Muscle Injuries: Clinical Experience -- 17.4 Tips for PRP Use for Muscle Injuries -- 17.5 Conclusion -- References -- 18: Bone Marrow Aspirate Concentrates for Knee OA -- 18.1 Introduction -- 18.1.1 Safety and Contraindications -- 18.2 Bone Marrow Tissue -- 18.2.1 Bone Marrow-Specific Regions -- 18.2.2 Bone Marrow Niches -- 18.2.3 Bone Marrow Aspiration -- 18.3 BMAC Procedural Preparations -- 18.3.1 BMA Harvesting Sites -- 18.3.2 Imaging Options -- 18.3.2.1 Ultrasound -- 18.3.2.2 Fluoroscopy -- 18.3.3 Cortical Bone Penetration Options -- 18.3.4 Anesthetic Considerations -- 18.3.5 BMA Harvesting Needle Devices -- 18.3.6 Anticoagulation with Heparin Solution -- 18.3.7 Extraction/Collection Syringes -- 18.3.8 BMAC Device Function -- 18.4 BMC Injection Knee Osteoarthritis -- 18.4.1 Background -- 18.4.2 Intra-articular Setup -- References -- 19: Fat-Derived Orthobiologics for Knee OA -- 19.1 Introduction -- 19.1.1 Safety and Contraindications -- 19.2 Adipose Tissue Background -- 19.2.1 Adipose Tissue Structure -- 19.2.2 Adipose-Derived Tissue Stem Cells -- 19.2.3 Adipose Harvesting Technique Considerations -- 19.3 Preparation of Minimally Manipulated Products from Adipose Tissue -- 19.3.1 Adipose Tissue Concentrate. 327 $a19.3.2 Micro-fragmented Adipose Tissue (MFAT) -- 19.3.3 Stromal Vascular Fraction (SVF) -- 19.3.4 SVF by Enzymatic Digestion -- 19.4 SVF by Mechanical Disruption -- 19.5 Adipose Tissue Orthobiological Properties -- 19.5.1 Immunomodulation -- 19.5.2 Angiogenesis -- 19.6 Adipose-Derived Products in Knee Osteoarthritis -- References -- 20: Autologous Conditioned Serum (ACS) -- 20.1 Background -- 20.2 Mechanisms of Action -- 20.2.1 Inflammatory Modulation -- 20.2.2 Growth Factors and Cytokines -- 20.3 Clinical Applications, Indication, and Dosage of Autologous Conditioned Serum Therapy -- 20.3.1 Osteoarthritis -- 20.3.2 Tendinopathies -- 20.3.3 Ligament Injuries -- 20.3.4 Other Musculoskeletal Conditions -- 20.3.5 Epidural Peri-radicular Injection for Back Pain -- 20.4 Application of ACS -- 20.5 Side Effects and Contraindications -- 20.6 Future Perspectives and Conclusion -- References -- 21: Alpha-2-Macroglobulin Concentrate as Orthobiologic in Osteoarthritis -- 21.1 Introduction -- 21.1.1 Safety and Contraindications -- 21.2 General Background A2M Protein Complex -- 21.2.1 Pharmacological Aspects A2M -- 21.2.2 Growth Factors, Cytokines, and A2M Application -- 21.3 Modulating Inflammation and Cartilage Degradation in OA -- 21.3.1 The Protective Effects of A2M in Synovial Fluid (SF) -- 21.4 Procedural Steps Producing A2M as Orthobiologic Injectate -- 21.4.1 Ultrafiltration Process -- 21.4.2 Clinical A2M Preparation Techniques -- 21.5 Clinical Data -- 21.6 Future Directions -- References -- Part IV: Injections of Anatomical Regions and Diseases -- 22: Injections of Anatomical Regions and Diseases: Shoulder -- 22.1 Sternoclavicular Joint -- 22.1.1 Anatomy and Biomechanics -- 22.1.2 Pathologies and Indication for Injections -- 22.1.3 Appliances -- 22.1.4 Agents -- 22.1.5 Injection Technique -- 22.1.6 Aftercare. 327 $a22.2 Acromioclavicular Joint -- 22.2.1 Anatomy and Biomechanics -- 22.2.2 Pathologies and Indication for Injections -- 22.2.3 Appliances -- 22.2.4 Agents -- 22.2.5 Injection Technique -- 22.2.6 Aftercare -- 22.3 Subacromial Bursa -- 22.3.1 Anatomy and Biomechanics -- 22.3.2 Pathologies and Indication for Injections -- 22.3.3 Appliances -- 22.3.4 Agents -- 22.3.5 Injection Technique -- 22.3.6 Aftercare -- 22.4 Glenohumeral Joint -- 22.4.1 Anatomy and Biomechanics -- 22.4.2 Pathologies and Indication for Injections -- 22.4.3 Appliances -- 22.4.4 Agents -- 22.4.5 Injection Technique -- 22.4.6 Aftercare -- References -- 23: Injections of Anatomical Regions and Diseases: Elbow -- 23.1 Elbow -- 23.1.1 Anatomy, Diagnosis, and Indications -- 23.1.2 Type of Injections and Agents -- 23.1.3 Technique/Tricks/Pitfalls -- 23.1.4 Aftercare -- 23.2 Radial Tuberosity (Biceps Tendon Insertion) -- 23.2.1 Anatomy, Diagnosis, and Indications -- 23.2.2 Technique/Tricks/Pitfalls -- 23.2.3 Type of Injections and Agents -- 23.2.4 Aftercare -- 23.3 Lateral Epicondylitis -- 23.3.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents -- 23.3.2 Technique/Tricks/Pitfalls -- 23.3.3 Aftercare -- 23.4 Medial Epicondylitis -- 23.4.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents -- 23.4.2 Technique/Tricks/Pitfalls -- 23.4.3 Aftercare -- 23.5 Olecranon Bursitis -- 23.5.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents -- 23.5.2 Technique/Tricks/Pitfalls -- 23.5.3 Aftercare -- 23.6 Conclusions -- References -- 24: Injections of Anatomical Regions and Diseases: Wrist and Hand -- 24.1 Wrist Joint -- 24.1.1 Anatomy -- 24.1.2 Indication and Diagnosis -- 24.1.3 Appliances -- 24.1.4 Agents -- 24.1.5 Technique/Tricks/Pitfalls -- 24.1.6 Aftercare -- 24.2 Distal Radioulnar Joint -- 24.2.1 Anatomy. 327 $a24.2.2 Indication and Diagnosis. 330 $aThis book presents a comprehensive and updated overview of musculoskeletal injections with biologic and non-biologic injectable agents ? a new trend of treatment in orthopaedics and sports medicine. This ESSKA book incorporates internal ongoing debates fostered by ESSKA U45 Committee and ESSKA?s Orthobiologics Initiative (ORBIT), which enroll a broad international group of dedicated clinicians and researchers. The topics covered mirror this fast evolving field which ranges from basic science knowledge to treatment options in sports traumatology. Renowned experts in the field examine and critically discuss each aspect, including existing controversies concerning indications and applications as well as the choice between biologic and non-biologic injections. Clear practical indications, subdivided by anatomical region and supported by a wealth of intra-procedural images, are aimed to support young surgeons in the application of musculoskeletal injections. Written by an international panel of clinicians and researchers, active in the field of orthobiology and sports medicine, this manual is an invaluable reference tool for all those involved in injectional therapies and sports traumatology. 606 $aOrthopedics 606 $aSports medicine 606 $aRegenerative medicine 606 $aOrthopaedics 606 $aSports Medicine 606 $aRegenerative Medicine and Tissue Engineering 615 0$aOrthopedics. 615 0$aSports medicine. 615 0$aRegenerative medicine. 615 14$aOrthopaedics. 615 24$aSports Medicine. 615 24$aRegenerative Medicine and Tissue Engineering. 676 $a616.7 700 $aKocaoglu$b Baris$01734226 701 $aLaver$b Lior$01734227 701 $aGirolamo$b Laura de$01734228 701 $aCompagnoni$b Riccardo$01734229 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910845486703321 996 $aMusculoskeletal Injections Manual$94150858 997 $aUNINA