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101 0 $aeng
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181   $ctxt
182   $cc
183   $acr
200 00$aNeuronal and cognitive effects of oestrogens$b[electronic resource]
210   $aChichester ;$aNew York $cWiley$d2000
215   $a1 online resource (294 p.)
225 1 $aNovartis Foundation symposium ;$v230
300   $a"Symposium on Neuronal and Cognitive Effects of Oestrogens, held at the Novartis Foundation, London, 7-9 September 1999"--P. v.
311   $a0-471-49203-5 
320   $aIncludes bibliographical references and index.
327   $aNEURONAL AND COGNITIVE EFFECTS OF OESTROGENS; Contents; Participants; Chairman's introduction; Mechanism of oestrogen signalling with particular reference to the role of ERb in the central nervous system; Discussion; Oestrogen receptor function at classical and alternative response elements; Discussion; General discussion I; Nuclear receptor versus plasma membrane oestrogen receptor; Discussion; Novel sites and mechanisms of oestrogen action in the brain; Discussion; Oestrogen modulation of noradrenaline neurotransmission; Discussion
327   $aOestrogen and the cholinergic hypothesis: implications for oestrogen replacement therapy in postmenopausal womenDiscussion; Ovarian steroid action in the serotonin neural system of macaques; Discussion; Oestrogen effects on dopaminergic function in striatum; Discussion; General discussion II; Oestrogen effects in olivo-cerebellar and hippocampal circuits; Discussion; Effects of oestradiol on hippocampal circuitry; Discussion; Oestrogen and cognitive function throughout the female lifespan; Discussion; Neuroprotective effects of phenolic A ring oestrogens; Discussion
327   $aThe female sex hormone oestrogen as neuroprotectant: activities at various levelsDiscussion; Neurohormonal signalling pathways and the regulation of Alzheimer b-amyloid metabolism; Discussion; Oestrogens and dementia; Discussion; Index of contributors; Subject index
330   $aAlthough normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the mammalian brain.This exciting book brings together leading clinicians and researchers to discuss oestrogen's basic mechanisms of action, the extrahypothalmic brain regions it affects, and its influence on cognitive functions in animals and h
410  0$aNovartis Foundation symposium ;$v230.
606   $aEstrogen$xPhysiological effect$vCongresses
606   $aNeuroendocrinology$vCongresses
606   $aNeurohormones$vCongresses
615  0$aEstrogen$xPhysiological effect
615  0$aNeuroendocrinology
615  0$aNeurohormones
676   $a572
676   $a612.405
676   $a612.6/2
712 12$aSymposium on Neuronal and Cognitive Effects of Oestrogens$f(1999 :$eLondon, England)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910841535103321
996   $aNeuronal and cognitive effects of oestrogens$94138014
997   $aUNINA