LEADER 00995nam0-22003491i-450- 001 990003819740403321 005 20070529122119.0 010 $a88-435-6999-6 035 $a000381974 035 $aFED01000381974 035 $a(Aleph)000381974FED01 035 $a000381974 100 $a20030910d1999----km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $aRomei e giubilei$eil pellegrinaggio medievale a San Pietro (350-1350)$fa cura di Mario D'Onofrio 210 $aMilano$cElecta$dc1999 215 $a473 p.$cill.$d28 cm 300 $aCatalogo della Mostra, Roma, Palazzo Venezia, 1999-2000 610 0 $aPellegrinaggi 610 0 $aItinerari sacri 676 $a306.69 702 1$aD'Onofrio,$bMario 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990003819740403321 952 $a306.691446 DON 1$b90$fBFS 952 $aCI.02.152$b71$fCICE 959 $aCICE 959 $aBFS 996 $aRomei e giubilei$9506134 997 $aUNINA LEADER 03825nam 2200673Ia 450 001 9910831177003321 005 20230721032628.0 010 $a1-281-32226-1 010 $a9786611322267 010 $a0-470-75125-8 010 $a0-470-75126-6 035 $a(CKB)1000000000536043 035 $a(EBL)354713 035 $a(SSID)ssj0000166069 035 $a(PQKBManifestationID)11169385 035 $a(PQKBTitleCode)TC0000166069 035 $a(PQKBWorkID)10146497 035 $a(PQKB)10478831 035 $a(SSID)ssj0000388265 035 $a(PQKBManifestationID)12091777 035 $a(PQKBTitleCode)TC0000388265 035 $a(PQKBWorkID)10423634 035 $a(PQKB)23779775 035 $a(MiAaPQ)EBC354713 035 $a(OCoLC)264389559 035 $a(EXLCZ)991000000000536043 100 $a20070626d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGrowth factors and psychiatric disorders$b[electronic resource] 210 $aChichester, UK ;$aHoboken, NJ $cJohn Wiley & Sons$d2008 215 $a1 online resource (260 p.) 225 1 $aNovartis Foundation symposium ;$v289 300 $a"Editors: Derek J. Chadwick (organizer) and Jamie Goode"--P. v. 311 $a0-470-51604-6 320 $aIncludes bibliographical references and indexes. 327 $aGROWTH FACTORS AND PSYCHIATRIC DISORDERS; Contents; Chair's introduction; Phenomenology, aetiology and treatment of schizophrenia; DISCUSSION; Genetic variants in major depression; DISCUSSION; Neurotrophins in depression and antidepressant effects; DISCUSSION; Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism; DISCUSSION; Mechanisms of neuregulin action; DISCUSSION; General discussion I; The fibroblast growth factor family and mood disorders; DISCUSSION; Trajectories of anatomic brain development as a phenotype; DISCUSSION 327 $aCell biology of BDNF and its relevance to schizophreniaDISCUSSION; Functions and mechanisms of BDNF mRNA trafficking; DISCUSSION; Hippocampal neurogenesis and depression; DISCUSSION; Neuregulins and neuronal plasticity: possible relevance in schizophrenia; DISCUSSION; Impact of genetic variant BDNF (Val66Met) on brain structure and function; DISCUSSION; General discussion II; Growth and schizophrenia: aetiology, epidemiology and epigenetics; DISCUSSION; What can we learn from the disrupted in schizophrenia 1 interactome: lessons for target identification and disease biology?; DISCUSSION 327 $aNeurotrophins and cytokines in neuronal plasticityDISCUSSION; Closing remarks; Contributor Index; Subject Index 330 $aThe recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical mechanisms. For example, recent studies have substantiated the provocative finding that neuregulin 1 (NRG1)is a candidate gene for schizophrenia. Neuregulin and its receptors, the ErbB tyrosine kinases, are essential for development 410 0$aNovartis Foundation symposium ;$v289. 606 $aGrowth factors 606 $aMental illness$xGenetic aspects 615 0$aGrowth factors. 615 0$aMental illness$xGenetic aspects. 676 $a616.89042 701 $aChadwick$b Derek$091632 701 $aGoode$b Jamie$0283336 712 02$aNovartis Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910831177003321 996 $aGrowth factors and psychiatric disorders$93926801 997 $aUNINA